Macromolecular Biochemistry

Research examines the structure and function of carbohydrates, proteins and nucleic acids to understand their biological roles in health and disease and to exploit them for diagnostics and therapeutics. Approaches include proteomics, x-ray crystallography, electron cryomicroscopy, computational modeling, in vitro evolution and spectroscopy.

Audas Lab

Understanding the role of noncoding RNA in the reversible formation of amyloid aggregates.

EMAIL: 

TIM AUDAS
taudas@sfu.ca

LAB ROOM: 

SSB 7166

LAB PHONE:

(778) 782-3904

Craig Lab

The bacterial Type IV pilus apparatus is a remarkable molecular machine that rapidly assembles and disassembles protein polymers to perform diverse functions related to microbial pathogenesis.

EMAIL: 

LISA CRAIG
licraig@sfu.ca

LAB ROOM: 

SSB 7169

LAB PHONE:  

(778) 782-7141

 

King Lab

We explore the structural and biochemical basis of microbial metabolite sensing.

 

EMAIL: 

DUSTIN KING
dustink@sfu.ca

LAB ROOM:

SSB 7166

LAB PHONE: 

(778) 782-3904

Larijani Lab

We are interested in genome-mutating processes.

EMAIL: 

MANI LARIJANI
mani_larijani@sfu.ca

Please note: All position enquiries for the Larijani Lab must be directed to larijani.lab.sfu@gmail.com

LAB ROOM:

SSB 6159

LAB PHONE: 

(778) 782-6817

Paetzel Lab

We investigate enzyme structure and mechanism.

EMAIL: 

MARK PAETZEL
mpaetzel@sfu.ca

LAB ROOM: 

SSB 6156

LAB PHONE:

(778) 782-4318

Setiaputra Lab

Our lab seeks to understand the molecular mechanisms underlying the mammalian DNA damage response. We are driven by our desire to better understand this fundamental aspect of our biology as well as the potential to manipulate DNA repair processes in genotoxic cancer therapy and gene editing.

EMAIL: 

Dheva Setiaputra
dsetiapu@sfu.ca

LAB ROOM:

SSB 6134

LAB PHONE: 

(778) 782-5785

Unrau Lab

The ability of RNA to recognize small substrates and promote difficult chemistry is poorly understood but is required to provide a solid foundation for the RNA world hypothesis.

EMAIL: 

PETER UNRAU
punrau@sfu.ca

LAB ROOM: 

SSB 6170

LAB PHONE: 

(778) 782-4894

Vocadlo Lab

We create new chemical and biochemical probes of glycan processing enzymes and use these to evaluate the roles of interesting glycoconjugates in cellular processes and diseases.

EMAIL: 

DAVID VOCADLO
dvocadlo@sfu.ca

LAB ROOM: 

TASC II 8060

LAB PHONE: 

(778) 782-7015

Young Lab

Structural and energetic principles of conformational switching in ion channels and other signaling proteins

EMAIL: 

EDGAR YOUNG
youngec@sfu.ca

LAB ROOM: 

SSB 7159

LAB PHONE: 

(778) 782-5645