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Department of Chemistry
Yu Lab: Materials and Surfaces for Sensing
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Papers (2001-2010)

  1. Ge, B.; Huang, Y. C.; Sen, D.; Yu, H.-Z. A robust electronic switch made of immobilized duplex/quadruplex DNA, Angew. Chem. Int. Ed. 2010, 49, 9965-9967.
  2. Pallapa, M.; Ou, L. M. L.; Parameswaran, M.; Yu, H.-Z., Software-based quantitation of bioassays-on-CD, Sens. Actuators B 2010, 148, 620–623.
  3. Popoff, R. T. W.; Asanuma, H.; Yu, H. Z.; Long-term stability and electrical performance of organic monolayers on hydrogen-terminated silicon, J. Phys. Chem. C 2010, 114, 10866–10872.
  4. Xiang, D.; Gao, G.; Shao, H.; Li, H.; Zhang, H.-L.; Yu, H.-Z., Redox behavior and ion-pairing thermodynamics of ferrocene and its derivatives in the organic phase, J. Phys. Chem. C 2010, 114, 617–621. 
  5. Asanuma, H.; Noguchi, H.; Uosaki, K.; Yu, H.-Z., Water structure at superhydrophobic quartz / water interfaces: a vibrational sum frequency generation spectroscopy study, J. Phys. Chem. C 2009, 113, 21155-21161.
  6. Asanuma, H.; Noguchi, H.; Huang, Y.; Uosaki, K.; Yu, H.-Z., Probing the molecular conformation of self-assembled monolayers at metal/semiconductor interfaces by vibrational sum frequency generation spectroscopy,  J. Phys. Chem. C 2009, 113, 21139-21146.
  7. Cheng, A. K. H.; Sen, D.; Yu, H.-Z., Design and testing of aptamer-based electrochemical biosensors for small molecules and proteins, Bioelectrochemistry 2009, 77, 1-12 (invited review).
  8. Chakraborty, B.; Jiang, Z.; Li, Y.; Yu, H.-Z., Rational design and performance testing of aptamer-based electrochemical biosensors for adenosine, J. Electroanal. Chem. 2009, 635, 75-82.
  9. Cheng, A. K. H.; Su, H.; Wang, Y. A.; Yu, H.-Z., Aptamer-based detection of epithelial tumor marker mucin 1 with quantum dot-based fluorescence readout, Anal. Chem. 2009, 81, 6130-6139.
  10. Huang, Y.-C.; Cheng, A. K. H.; Yu, H.-Z.; Sen, D. The charge conduction properties of a parallel-stranded DNA G-quadruplex: implications for chromosomal oxidative damage, Biochemistry  2009, 48, 6794–6804. 
  11. Murphy, J. N.; Cheng, A. K. H.; Yu, H.-Z.; Bizzotto, D., On the nature of DNA self-assembled monolayers on Au: measuring surface heterogeneity with electrochemical in situ fluorescence microscopy, J. Am. Chem. Soc. 2009, 131,  4042-4050. Featured in: Analytical Chemistry Latest News, DNA aggregates detected as hot spots in electrofluorescence of SAMs, March 26, 2009.
  12. Li, Y. C.; Li, P. C. H.; Parameswaran, M.; Yu, H.-Z., Inkjet printed electrode arrays for potential modulation of DNA self-assembled monolayers on gold, Anal. Chem. 2008, 80, 8814-8821.
  13. Li, Y. C.; Ou, L. M. L.; Yu, H.-Z., Digitized molecular diagnostics: Reading disc-based bioassays with standard computer drives, Anal. Chem. 2008, 80, 8216-8223. Featured in: SpectroscopyNow, DIY Instrumentation, Nov. 1, 2008; and by Erickson, J. S.; Ligler, F. S., Home diagnostics to music, Nature 2008, 456, 178-179.  
  14. Wang, M. C. P.; Li, Y.-C.; Merbouh, N.; Yu, H.-Z., Thin-layer electrochemistry of ferrocenylbenzene derivatives: intramolecular electronic communication, Electrochimi. Acta 2008, 53, 7720-7725. 
  15. Katz, M.; Ramnial, T.; Yu, H. Z.; Leznoff, D. B., Polymorphism of Zn[Au(CN)2]2 and its luminescent sensory response to NH3 vapor, J. Am. Chem. Soc. 2008, 130, 10662-10673.
  16. Huang, Y. C.; Ge, B.; Sen, D.; Yu, H. Z., Immobilized DNA switches as electronic sensors for picomolar detection of plasma proteins, J. Am. Chem. Soc. 2008, 130, 8023-8029.
  17. Asanuma, H.; Noguchi, H.; Uosaki, K.; Yu, H. Z., Metal cation-induced deformation of DNA self-assembled monolayers on silicon, J. Am. Chem. Soc. 2008, 130, 8016-8022.
  18. Kuikka, M. A.; Li, W.; Kavanagh, K. L.; Yu, H. Z., Nanoscale electrical and structural characterization of gold/molecular-monolayer/silicon junctions, J. Phys. Chem. C 2008, 112, 9081-9088. 
  19. Wang, L.; Li, P. C. H.; Yu, H. Z.; Parameswaran, M., Fungal pathogenic nucleic acid detection achieved with a microfluidic microarray device, Anal. Chim. Acta 2008, 610, 97-104.
  20. Soolaman, D. M.; Yu, H. Z., Monolayer-directed electrodeposition of oxide thin films: surface morphology versus chemical modification, J. Phys. Chem. C 2007, 111, 14157-14164.
  21. Peng, X. Y.; Li, P. C. H.; Yu, H. Z.; Parameswaran, M.; Chou, W. L., Spiral microchannels on a CD for DNA hybridizations, Sens. Actuators B  2007, 128, 64-69.
  22. Cheng, A. K. H.; Ge, B. X.; Yu, H. Z., Aptamer-based biosensors for label-free voltammetric detection of lysozyme, Anal. Chem. 2007, 79, 5158-5164.
  23. Cheng, A. K. H.; Soolaman, D. M.; Yu, H. Z., “Non-evaporating” microdroplets on self-assembled monolayer surfaces under ambient conditions, J. Phys. Chem. B 2007, 111, 7561-7566. Featured in: Science 2007, 316, 1670: Droplets Hanging Around (Editors’ Choice).
  24. Cho, H.; Parameswaran, M.; Yu, H. Z., Fabrication of microsensors using unmodified office inkjet printers, Sens. Actuators B 2007, 123, 749-756. Featured in: Spectroscopy Now, Print yourself a spectrometer, Nov. 1, 2006.
  25. Ge, B.; Huang, Y.-C.; Sen, D.; Yu, H. Z., Electrochemical investigation of DNA-modified surfaces: From quantitation methods to experimental conditions, J. Electroanal. Chem.  2007, 602, 156-162.
  26. Li, Y.; Wang, Z.; Ou, L. M. L.; Yu, H. Z., DNA detection on plastic: surface activation protocol to convert polycarbonate substrates to biochip platforms, Anal. Chem. 2007, 79, 426-433. Featured as one of the most accessed articles in Analytical Chemistry (Jan-Mar 2007). 
  27. Asanuma, H.; Bishop, E. M.; Yu, H. Z., Electrochemical impedance and solid-state electrical characterization of silicon (111) modified with w-functionalized alkyl monolayers, Electrochim. Acta 2007, 52, 5913-5919.
  28. Cheng, A. K. H.; Soolaman, D. M.; Yu, H. Z. Evaporation of microdroplets of ethanol-water mixtures on gold surfaces modified with self-assembled monolayers, J. Phys. Chem. B 2006, 110, 11267-11271.
  29. Li, Y. C.; Tsang, E. M. Y.; Chan, A. Y. C.; Yu, H. Z., Thin-layer electrochemistry of 1,3,5-triferrocenylbenzene: a unique two-step, three-electron process, Electrochem. Commun. 2006, 8, 951-955.
  30. Asanuma, H.; Noguchi, H.; Uosaki, K.; Yu, H. Z., Structure and reactivity of alkoxycarbonyl (ester)-terminated monolayers on silicon: sum-frequency generation spectroscopy, J. Phys. Chem. B 2006, 110, 4892-4899.
  31. Su, L.; Sen, D.; Yu, H. Z., Voltammetric study of the ion-exchange binding of non-electroactive metal cations to DNA-modified surfaces, Analyst 2006, 131, 317-322 (Emerging Investigators special issue).
  32. Soolaman, D. M.; Yu, H. Z., Water microdroplets on molecularly tailored surfaces: correlation between wetting hysteresis and evaporation mode switching, J. Phys. Chem. B 2005, 109, 17967-17973.  
  33. Asanuma, H.; Lopinski, G. P.; Yu, H. Z., Kinetic control of the photochemical reactivity of hydrogen-terminated silicon with bifunctional molecules, Langmuir 2005, 21, 5013-5018.
  34. Asanuma, H.; Liu, Y. J.; Yu, H. Z., A versatile portable device for solid-state electrical measurements of “soft” materials, Jpn. J. Appl. Phys. 2005, 44, 1991-1993.
  35. Ho, C.; Soolaman, D. M.; Yu, H. Z., Analytical/materials chemistry on recordable CDs: beyond self-assembly, Can. J. Chem. 2005, 83, 403-412 (CSC Fred Beamish Award Lecture; featured as cover picture).
  36. Yang, M.; Tsang, E. M. Y.; Wang, Y. A.; Peng, X. G.; Yu, H. Z., Bioreactive surfaces prepared via self-assembly of dendron thiols and subsequent dendrimer bridging reactions, Langmuir 2005, 21, 1858-1865.
  37. Yu, H. Z., New chemistry on old CDs, Chem. Commun. 2004, 2633-2636 (Focus Article; featured as cover picture; most accessed paper in December 2004).
  38. -Dickie, D. A.; Chan, A. Y. C.; Jalali, H.; Jenkins, H. A.; Yu, H. Z.; Clyburne, J. A. C. m-Terphenyl thiols: rigid and bulky molecules for the formation of bioactive self-assembled monolayers on gold, Chem. Commun. 2004, 2432-2433.
  39. Su, L.; Sankar, C. G.; Sen, D.; Yu, H. Z., Kinetics of the ion-exchange binding of redox metal cations to thiolate-DNA monolayers on gold, Anal. Chem. 2004, 76, 5953-5959.
  40. Yu, H. Z.; Soolaman, D. M.; Rowe, A. W.; Banks, J. T., Evaporation of Water Micro-droplets on Self-Assembled Monolayers: From Pinning to Shrinking, ChemPhysChem  2004, 5, 1035-1038. 
  41. Xu, J.; Frcic, A.; Clyburne, J. A. C.; Gossage, R. A.; Yu, H. Z., Thin-layer electrochemistry of 1,3-diferrocenyl-2-buten-1-one: direct correlation between driving force and liquid/liquid interfacial electron transfer rates, J. Phys. Chem. B 2004, 108, 5742-5746.
  42. Liu, Y. J.; Navasero, N. M.; Yu, H. Z., Formation and reactivity of mixed w-carboxyalkyl / alkyl monolayers on silicon: ATR-FTIR spectroscopy and contact angle titration, Langmuir 2004, 20, 4039-4050.
  43. Liu, Y. J.; Yu, H. Z., Effect of organic contamination on the electrical degradation of hydrogen-terminated silicon upon exposure to air under ambient conditions, J. Electrochem. Soc. 2003, 150, G861-G865.
  44. Liu, Y. J.; Yu, H. Z., Molecular passivation of classical mercury-silicon (p-type) diode junctions: alkylation, oxidation, and alkylsilation, J. Phys. Chem. B 2003, 107, 7803-7811.
  45. Yu, H. Z., Luo, C. Y.; Sankar, C. G.; Sen, D. Voltammetric procedure for examining DNA-modified surfaces: quantitation, cationic binding activity, and electron-transfer kinetics, Anal. Chem. 2003, 75, 3902-3907.
  46. Liu, Y. J.; Yu, H. Z.; Alkyl monolayer-passivated metal-semiconductor diodes: 2. Comparison with native silicon oxide, ChemPhysChem 2003, 4, 335-342.
  47. Liu, Y. J.; Waugh, D. M.; Yu, H. Z., Impact of organic contamination on the electrical properties of hydrogen-terminated silicon under ambient conditions, Appl. Phys. Lett.  2002, 81, 4967-4969.
  48. Yu, H. Z.; Rowe, A. W.; Waugh, D. M., Templated electrochemical deposition of zirconia thin films on “Recordable CDs”, Anal. Chem. 2002, 74, 5742-5747. Featured in: The Scientist, November 11, 2002, page 10: Array on an old CD
  49. Liu, Y. J.; Yu, H. Z., Alkyl monolayer-passivated metal-semiconductor diodes: 1. Molecular tunability and electron transport, ChemPhysChem  2002, 3, 799-802.
  50. Banks, J. T.; Yu, T. T.; Yu, H. Z., Direct visualization of the hydrolysis kinetics of titanium (IV) alkoxides on functionalized gold surfaces, J. Phys. Chem. B 2002, 106, 3538-3542.
  51. Yu, H. Z., Self-assembly on “recordable CDs”, Anal. Chem. 2001, 73, 4343-4347. Featured in: Photonics Spectra, December 2001, page 50: Recordable CDs are sources of gold substrates; Canadian Chemical News (ACCN), February 2002, page 10: Prospecting for gold​
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