Sun Lab

Bingyun Sun,* Cynthia Lorang, Shizhen Qin, Yijuan Zhang, Ken Liu, Gray Li, Zhi Sun, Ashley Francke, Angelita G. Utleg, Zhiyuan Hu, Kai Wang, Robert L. Moritz, and Leroy Hood*

Cells, 2021, 10(12), 3449

Characterization of Sample Loss Caused by Competitive Adsorption of Proteins in Vials Using Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

Ameya V Ranade, Rustam Mukhtarov, Ken Jia An Liu, Melissa A. Behrner, Bingyun Sun*

Langmuir, 2019, 35(12), 4224-4232

Synthesis and characterization of a photoaffinity labelling probe based on the structure of the cystic fibrosis drug ivacaftor

Hamilton, M. C.; Hung, M.; Chen, G,; Qureshi, Z.; Thompson, J. R.; Sun, B.; Bear, C. E.; Young, R. N.*

Tetrahedron, 2018, 74(38), 5528-5538

Quantitation of Non-Specific Protein Adsorption at Solid-Liquid Interfaces for Single-Cell Proteomics

Man Chung Gilbert Lee and Bingyun Sun*

Can. J. Chem., 2018, 96(2), 102-109

Optimization and Modeling of Quadrupole Orbitrap Parameters for Sensitive Analysis toward Single-Cell Proteomics

Bingyun Sun*, Jessica Rae Kovatch, Albert Badiong, and Nabyl Merbouh

J. Proteome Res., 2017, 16(10), 3711-3721

Reported by GenomeWeb, Simon Fraser Team Models Ideal Mass Spec Settings for Single-Cell Proteomics.

Method Comparison for Analyzing Wound Healing Rates

Dhillon, P. K.; Li, X; Sanes, J. T.; Akintola, O. S.; Sun, B.*

Biochemistry and Cell Biology, 2017, 95(3), 450-454

Membrane Gene Ontology Bias in Sequencing and Microarray Obtained by Housekeeping-Gene Analysis

Zhang, Y.; Akintola,S. O.; Liu, J. K.; and Sun, B.*

GENE, 2016, 575 (2 Pt2), 559-566

Detection Bias in Microarray and Sequencing Transcriptomic Analysis Identified by Housekeeping Genes

Zhang, Y.; Akintola,S. O.; Liu, J. K.; and Sun, B.*

Data In Brief, 2015, 6, 121-123

Do Housekeeping Genes Exist?

Zhang, Y.; Li, D.; and Sun, B.*

PLOS ONE, 2015, 10(5), e0123691. doi: 10.1371/journal.pone.0123691

Reported by Phys.org, Study questions existence of housekeeping genes.

Proteomics and Glycoproteomics of Pluripotent Stem-Cell Surface Proteins

Sun, B.*

Proteomics, 2015, 15(5-6), 1152-1163

Sodium Dodecyl Sulfate Polyacrylamide Gel Eletrophoresis for Direct Quantitation of Protein Adsorption

Lee, G.; Wu, K.; Nguyen, T. and Sun, B.*

Analytical Biochemistry, 2014, 465C, 102-104

Protein-Centric N-GlycoProteomics Analysis of Membrane and Plasma Membrane Proteins

Sun, B.* and Hood, L.

Journal of Proteome Research, 2014, 13(6), 2705-2714.

Glycopeptide Capture for Cell Surface Proteomics

Lee, G. and Sun, B.*

JoVE, 2014, 87, doi: 10.3791/51349.

Glycocapture-Assisted Global Quantitative Proteomics (gagQP) Reveals Multiorgan Responses in Blood Toxicoproteome

Sun, B.*; Ranish, J.A.; Utleg, A.G.; Hu, Z.; Keller, A.; Qin, S., Lorang, C.; Gray, L.; Brightman, A.; Lee, D.; Alexander, V.M.; Moritz, R.L.; Hood, L.*

Journal of Proteome Research, 2013, 12 (5), 2034–2044.

Reported by GenomeWeb, Proteomonitor, the noted publication.

N-glycoproteome of E14.Tg2a mouse embryonic stem cells

Sun, B.*; Ma, L.; Yan, X.; Lee, D.; Alexander, V.; Hohmann, L. J.; Lorang, C.; Chandrasena, L.; Tian, Q.; Hood, L.*

PLOS ONE, 2013, 8(2): e55722. doi: 10.1371/journal.pone.0055722.

Reported by Science Daily, “Discovering Cell Surface Proteins' Behavior”; Proteomonitor: “SFU Team Profiles N-Glycoproteome of Mouse Stem Cells, IDs Membrane Protein Glycosylation Pattern”; ACCN, the Canadian Chemical News: “Glycan capture technique sheds light on cell surface proteins” and by LC & GC chromatography online:“How do cells talk?”

Molecular Profiling of Stem Cells

Li, M.; Sun, B.; Hood, L.; Tian, Q.*

Clinica Chimica Acta, 2007, 378, 24-32.

Shotgun Glycopeptide-Capture Approach Coupled with Mass Spectrometry for Comprehensive Glycoproteomics

Sun, B.; Ranish, J. A.; Utleg, A. G.; White, J. T.; Yan, X.; Lin, B; Hood, L.*

Mol. Cell. Proteomics, 2007, 6, 141-149.

Highlighted in Journal of Proteome Research, “Isolating the glycoproteome from the bottom up”, 2007, 6, 17-19, doi: 10.1021/pr0707051; by Functional Glycomics, “One pot, one shot”, 2007, February 08, doi:10.1038/fg.2007.7

Layered Polyelectrolyte-Silica Coating for Nanocapsules

Sun, B.; Mutch, S.; Lorenz, R.; Chiu, D. T.*

Langmuir, 2005, 21, 10763-10769.

Determination of the Encapsulation Efficiency of Individual Vesicles Using Single-Vesicle Photolysis and Confocal Single-Molecule Detection

Sun, B. and Chiu, D. T.*

Anal. Chem., 2005, 77, 2770-2776.

Fast Initiation of Chemical Reactions with Laser-Induced Breakdown of a Nanoscale Partition

Sun, B.; Lim, S. D.; Kuo, J. S.; Kuyper, C. L.; Chiu, D. T.*

Langmuir, 2004, 20, 9437-9440.

Synthesis, Loading, and Application of Individual Nanocapsules for Probing Single-Cell Signaling

Sun, B.; and Chiu, D. T.*

Langmuir, 2004, 20, 4614-4620.

Spatially and Temporally Resolved Delivery of Stimuli to Single Cells

Sun, B.; and Chiu, D. T.*

J. Am. Chem. Soc. 2003, 125, 3702-3703.

Functional mapping of cell surface proteins with localized stimulation of single cells

Sun, B.; and Chiu, D. T.*

The Proceedings of SPIE, 2003, 5222 (Nanocrystals and Organic and Hybrid Nanomaterials), 118-125.

Kinetic studies on the oxidation of cytochrome b(5) Phe35 mutants with cytochrome c, plastocyanin and inorganic complexes

Yao, P.; Wang, Y. H.; Sun, B.; Xie, Y.; Hirota, S.; Yamauchi, O.; Huang, Z. X.*

J. Biol. Inorg. Chem. 2002, 7, 375-383.

X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b(5) Phe35-> Tyr mutant

Yao, P.; Wu, H.; Wang, Y. H.; Sun, B.; Xia, Z. X.; Huang, Z. X.*

Eur. J. Biochem. 2002, 269, 4287-4296.

Structures of cytochrome b(5) mutated at the charged surface- residues and their interactions with cytochrome c

Wu, J.; Wang, Y. H.; Gan, J. H.; Wang, W. H.; Sun, B.; Huang, Z. X.; Xia, Z. X.*

Chinese Journal of Chemistry 2002, 20, 1225-1234.

Electrostatic effect on electron transfer between cytochrome b(5) and cytochrome c

Huang, Z. X.*; Sun, B.; Wang, Y. H.; Wang, W. H.; Yao, P.; Xie, Y.

Prog. Nat. Sci. 2000, 10, 393-397.

Structure, interaction and electron transfer between cytochrome b(5), its E44A and/or E56A mutants and cytochrome c

Sun, Y. L.; Wang, Y. H.; Yan, M. M.; Sun, B.; Xie, Y.; Huang, Z. X.; Jiang, S. K.; Wu, H. M.*

J. Mol. Biol. 1999, 285, 347-359.

Expression and purification of a novel ZNF191 zinc finger protein - ZNF191 protein and its truncated zinc finger region ZNF191 (243-368)

Liu, Y. Q.; Yu, L.; Yu, W. H.; Shi, S. L.; Sun, B.; Wu, G. J.; Huang, Z. X.*

Sci. China Ser. B-Chem. 1999, 42, 245-252

Patents:

Sun, B. “Absolute quantification of nav1.5 expression by targeted mass spectrometry”, 2022/04/08, PPA No. 63/329164.

Aebersold, R.; Hood, L.; Zhang, H.; Sun, B. “Methods for quantitative proteome analysis of glycoproteins”, 2008/06/06, W.O. Patent No. 2008066629.

Aebersold, R.; Hood, L.; Zhang, H.; Sun, B. “Methods for quantitative proteome analysis of glycoproteins”, 2007, U.S. Patent No. 20070269895.

Chiu, D. T., Sun, B., Shelby, P. J., Kuo, J. S., Fiorni, G., He, M., Jeffries, G., Kuyper, C., Lim, D., Lorenz, R., Allen, P., Mutch, S., and Sun, C. “Integrated platform for chemical profiling of ultrasmall subcellular compartments from a single cell”, 2005, US patent No. 20050048581.