Publications, Posters and Presentations
Publications
- Watson, C.T., Steinberg, K.M., Huddleston, J., Warren, R.L., Malig, M., Schein, J., Willsey, A.J., Joy, J.B., Scott, J.K., Graves, T., Wilson, R.K., Holt, R.A., Eichler, E.E., and Breden, F. 2013. Complete Haplotype of the Human Immunoglobulin Heavy Variable IGHV genes from a Single Individual and Characterization of Allelic and Copy Number Variation from Haplotype Sequence Analysis. Am J Hum Genet. 92(4): 530-46.
- Scott, J.K., Pantophlet, R., Craig, L. 2012. Complex Binding Sites Made to Order. Nature Biotechnol. (News and Views.) 30(2): 154-155.
- Montero, M., Gulzar, N., Klaric, K.A., Donald, J., Lepik, C., Wu, S., Tsai, S., Julien, J.P., Hessell, A., Wang, S., Lu, S., Burton, D., Pai, E., DeGrado, W., and Scott, J.K. 2012. Neutralizing Epitopes in the MPER of HIV-1 gp41 Are Influenced by the Transmembrane Domain and the Plasma Membrane. J. Virol. 86(6): 2930-2941.
- Raymond-Bouchard, I., Carroll, C.S., Nesbitt, J.R., Henry, K.A., Pinto, L.J., Moinzadeh, M., Scott, J.K ., Moore, M.M. 2012. The MIRB Ferrisiderophore Transporter of Aspergillus fumigatus: Structural Requirements for Activity. Eukaryot Cell. 11(11): 1333-1344.
- Singh, H., Henry, K.A., Wu, S.S.T., Chruscinskia, A., Utz, P.J., and Scott, J.K. 2011.
Reactivity Profiles of Broadly Neutralizing Anti-HIV-1 Antibodies Are Distinct from Those of Pathogenic Autoantibodies. AIDS. 25(10): 1247-1257. - Henry, K.A., Murira, A., van Houten, N.E., Scott, J.K. 2011. Developing Strategies to Enhance and Focus Humoral Immune Responses Using Filamentous Phage as a Model Antigen. Bioeng Bugs. 2(5): 275-283.
- Romanuik, S.F., Grist, S.M., Gray, B.L., Hohertz, D., Kavanagh, K., Gulzar, N., Scott, J.K., Nirwan, R., Hui, C., Brolo, A.G. and Gordon, R. 2011. Detecting Antibodies Secreted by Trapped Cells Using Extraordinary Optical Transmission. IEEE Sensors. 11(11): 2732-2739.
- Romanuik, S.F., Grist, S.M., Haq, M., Gray, B.L., Gulzar, N., Scott, J.K., Hohertz, D., Kavanagh, K.L, Nirwan, R., Hui, C, Brolo, A.G. and Gordon, R. 2011. Microfluidic Trapping of Antibody-secreting Cells. J. Med. & Biol. Eng. 31(2): 121-127.
- Zhu, Z., Qin, H.R., Chen, W., Zhao, Q., Shen, X., Schutte, R., Wang, Y., Ofek, G., Streaker, E., Prabakaranm, P., Fouda, G.G., Liao, H.X., Owens, J., Louder, M., Yang, Y., Klaric, K.A., Moody, M.A., Mascola, J.R., Scott, J.K., Kwong, P.D., Montefiori, D., Haynes, B.F., Tomaras, G.D., Dimitrov, D.S. 2011. Cross-reactive HIV-1-neutralizing Human Monoclonal Antibodies Identified from a Patient with 2F5-like Antibodies. J Virol. 85(21): 11401-11408.
- Romanuik, S.F., Grist, S.M., Gray, B.L., Hohertz, D., Kavanagh, K., Gulzar, N., Scott, J.K., Nirwan, R., Hui, C., Brolo, A.G., and Gordon, R. 2010. Sensing of Antibodies Secreted by Microfluidically Trapped Cells via Extraordinary Optical Transmission through Nanohole Arrays. IEEE Sensors, 2105-2108.
- Breden, F., Lepik, C., Longo, N.S., Montero, M., Lipsky, P.E., Scott, J.K. 2010. Comparison of Antibody Repertoires Produced by HIV-1 Infection, Other Chronic and Acute Infections, and Systemic Autoimmune Disease. PLoS ONE 6(3): e16857.
- Irving, M.B., Craig, L., Menendez, A., van Houten, N.E., Montero, M. and Scott, J.K. 2010. Exploring Peptide Mimics for the Production of Antibodies against Discontinuous Protein Epitopes. Molec. Immunol. 47(5): 1137-1148.
- van Houten, N.E., Henry, K.A., Smith, G.P. and Scott, J.K. 2010. Engineering Filamentous Phage as a Carrier to Focus Antibody Responses against a Peptide. Vaccine 28(10): 2174-2185.
- Feldman, A.R., Shapova, Y.A., Wu, S.S.T., Oliver, D.C., Heller, M., McIntosh, L.P., Scott, J.K. and Paetzel, M. 2008. Phage Display and Crystallographic Analysis Reveals Potential Substrate/Binding Site Interactions in the Protein Secretion Chaperone CsaA from Agrobacterium tumefaciens. J. Mol. Biol. 379(3): 457-470.
- Menendez, A.*, Calarese, D.*, Stanfield, R.L.*, Chow, K.C., Scanlon, C., Kunert, R., Katinger, H., Burton, D.R., Wilson, I.A. ¶ and Scott, J.K. ¶ 2008. A Peptide Inhibitor of HIV-1 Neutralizing Antibody 2G12 Is Not a Structural Mimic of the Natural Carbohydrate Epitope on gp120. FASEB J. 22: 1380-1392. *These authors contributed equally to this work. ¶Co-corresponding authors.
- Montero, M. *, van Houten, N.E. *, Wang, X. and Scott, J.K. 2008. The Membrane Proximal External Region of the HIV-1 Envelope: A Dominant Site of Antibody Neutralization and Target for Vaccine Design. Microbiol. Mol. Biol. Rev. 72(1): 54-84. *These authors contributed equally to this work.
Posters and Presentations
Underline is presenter, italics is lab member.
- Murira, A., Henry, K.A., Ahmed,F.K., and Scott, J.K. Transcriptomic profiling of CD138+ cells from immunized mice indicates ontological heterogeneity. ImmunoBC 2015. Vancouver, BC. 11 June 2015.
- Marthandan, N., Henry, K.A., Murira, A.M., Nickel, K., Ahmed, F., Breden,F.J., and Scott, J.K. B receptor repertoire analysis to study antibody responses elicited by hyperimmunization with a bacteriophage. ImmunoBC 2015. Vancouver, BC. 11 June 2015.
- Gulzar, N., Ahmed, F.K., Rujas, E., Apellaniz, B., McCully, M.E., Wang,S., DeGrado, W.F., Nieva, J.L., Lu, S., and Scott, J.K. Durable Antibody Responses Against the 2F5 Region of the MPER of HIV gp41 are Elicited using Engineered DNA and Liposome Vaccines, and Co-Immunization Strategies. ImmunoBC 2015. Vancouver, BC. 11 June 2015.
- Breden, F., Marthandan, N., Zimonja, B., Jaglale,J., Scott,J.K., and Brian Corrie. iReceptor: Bioinformatic Platform for Storing and Sharing Next Generation Sequencing (NGS) Data from Immune Repetoires. ImmunoBC 2015. Vancouver, BC. 11 June 2015.
- Murira, A., and Scott, J.K. Transcriptomic profiling of CD138+ cells from immunized mice indicates ontological heterogeneity. Keystone Symposia: The Golden Anniversary of B Cell Discovery. Banff, Alberta. 22-27 March 2015.
- Henry, K.A., Murira, A.M., Marthandan, N., Nickel, K., Ahmed, F., Breden, F.J., and Scott,J.K. Immune profiling of IgM and IgG antibody response elicited by hyperimmunization with a virus-like particle. Keystone Symposia: The Golden Anniversary of B Cell Discovery. Banff, Alberta. 22-27 March 2015.
- Ahmed, F.K., Gulzar, N., Apellaniz, B., Rujas, E., McCullly, M.E., Hannigan, B., Ulas, G., Wang, S., and Scott, J.K. Immunization Strategies for Engineering DNA and Liposome Vaccines that Target the MPER of HIV gp41. Keystone Symposia: HIV Vaccines. Banff, Alberta. 22-27 March 2015.
- Murira, A., Henry, K.A., Nickel, K., and Scott, J.K. Murine B-cell Responses during Hyperimmunization with a Virus-like Particle. Antibody Engineering and Therapeutics. Huntington Beach, CA. 8-12 December 2013.
- Gulzar, N., McCully, M.E., Parfyonov, M., Klaric, K.A., Hannigan, B.T., Ulas, G., DeGrado, W.F., and Scott, J.K. Study 2: DNA Vaccines Expressing the Membrane Proximal External Region of HIV-1 gp41 to Optimize Exposure of Neutralizing Epitopes. AIDS Vaccine 2013. Barcelona, Spain. 6 October 2013.
- Gulzar, N., Ahmed, F., Rujas, E., Apellaniz, B., Klaric, K.A., Parfyonov, M., Huerte, N., Montero, M., Nieva, J., Lu, S., and Scott, J.K. Study 1: A DNA-prime, Liposome-boost Immunization Strategy Targeting the 2F5 Epitope of the Membrane Proximal External Region of HIV-1 gp41. AIDS Vaccine 2013. Barcelona, Spain. 6 October 2013.
- Gulzar, N., Klaric, K.A., Parfyonov , M., Montero, M., Wang, S., Huarte, N., Appellaniz, B., Nieva, J., Lu, S., and Scott, J.K. Study 1: Optimizing DNA Vaccines that Target the 2F5 Epitope of the Membrane Proximal External Region of HIV-1 gp41. AIDS Vaccine 2013. Barcelona, Spain. 6-11 October 2013.
- Gulzar, N., Klaric, K.A., Parfyonov, M., Montero, M., Hannigan, B., McCully, M., Ulas, G., Wang, S., Huarte, N., Appellaniz, B., Nieva, J., Lu, S., DeGrado, W.F., and Scott, J.K. DNA Vaccines that Optimally Present Neutralizing Epitopes within the Membrane Proximal External Region of HIV-1 gp41. ImmunoVancouver 2013. Vancouver, Canada. 13 June 2013.
- Bailey, J.J., Henry, K.A., Scott, J.K., and Bundle, D.R. An HIV-1 Glycoconjugate Vaccine Utlilizing Filamentous Phage as an Immunogenic Carrier. 9th Annual National Carbohydrate Symposium. Banff, Alberta. 8-10 May 2013.
- Gulzar, N., Klaric, K.A., Parfyonov, M., Montero, M., Hannigan, B., McCully, M., Ulas, G., Wang, S., Huarte, N., Appellaniz, B., Nieva, J., Lu, S., DeGrado, W.F., and Scott, J.K. DNA Vaccines that Optimally Present Neutralizing Epitopes within the Membrane Proximal External Region of HIV-1 gp41. Canadian Association for AIDS/HIV Research, 22nd Annual Meeting. Vancouver, Canada. 10 April 2013.
- Henry, K.A., Murira , A., Joy,J.B., Aghaeepour, N., Chen, W., Prabakaran, P., Dimatrov, D.S., Brinkman, R.R., Breden, F., and Scott, J.K. Tools for characterizing phenotypic and immunogenetics features of the B-cell response against HIV. Canadian Society for Immunology 2013. Whistler, BC. 5-8 April 2013.
- Bailey, J.J., Reiz, B., Henry, K.A., Scott, J.K., and Bundle, D.R. HIV-1 glycoconjugate vaccine utilizing filamentous bacteriophage as an immunogenic carrier. Canadian Society for Immunology 2013. Whistler, BC. 5 April 2013.
- Murira , A., Henry, K.A., and Scott, J.K. Murine B-cell responses during hyperimmunization with a virus-like particle. Canadian Society for Immunology 2013. Whistler, BC. 5-8 April 2013.
- Henry, K.A., Wang, X., Wang, C., Wu, S.S.T., Kingsley, L., Rinaldo, C.R. Jr, Richman, D.D., Silverman, G.J., and Scott, J.K. Serological profiling of antibody responses during HIV infection. Keystone Symposium on B cell Development (X1) and HIV Vaccines (X2). Keystone, CO, USA. 10-15 Feb 2013.
- Murira, A., Henry, K.A., Aghaeepour, N., Brinkman, R.R., Moir, S., and Scott, J.K. A systems immunology approach to investigate the antibody response during HIV infection. Keystone Symposium on B cell Development (X1) and HIV Vaccines (X2). Keystone, CO, USA. 10-15 Feb 2013.
- Murira, A., Henry, K.A., and Scott, J.K. Murine B-cell Responses during Hyperimmunization with a Virus-like Particle. Keystone Symposium on B cell Development (X1) and HIV Vaccines (X2). Keystone, CO, USA. 10-15 Feb 2013.