Mass Spectrometry Facility

Ultra-High Resolution Quadrupole | Time-of-Flight | LC/MS/MS System

• Sub-ppm mass accuracy and 40,000 Full-Sensitivity Resolution for complex, high-background matrices
• Market-leading isotopic fidelity for definitive molecular formulae determination with Smart Formula and Smart Formula 3D
• Extreme sensitivity across the entire mass range from very small molecules to intact proteins
• Specialty software packages: BioTools, ProfileAnalysis, MetaboliteTools, TargetAnalysis
• Electrospray Ionization Source (ESI Positive and Negative)
• Agilent 1200 SL LC System

• A benchtop MALDI-TOF instrument for fast and flexible analysis
• Suitable for a range of analyte types, such as small organic molecule, organometallic compounds, proteins and polymers
• Easy to use
• Walk-up service for trained users

nanoLC-MS/MS system for proteomics analysis

• Q-Exactive HF is a Hybrid Quadrupole-Orbitrap Mass Spectrometer, equipped with an Ultrahigh-Field Orbitrap, which provides accurate and highly sensitive detection of peptides in complex biological samples
• Easy nLC 1000 UHPLC delivers nanoliter per minute accurate and highly reproducible flow rate
• Easy-Spray nanoESI source with reliable and reproducible ionization for the state-of-the-art performance of both expert and nonexpert users
• High throughput (> 1000 proteins/h) and high sensitivity (attomole)
• Discovery based shotgun proteomics and targeted PRM analysis
• Accessible in Prof. B. Sun’s lab. Please contact bingyun_sun@sfu.ca for more info.