Mass Spectrometry Facility

Welcome to the Mass Spectrometry (MS) facility at Simon Fraser University. 

Our facility provides mass spectral services to researchers at SFU, other universities, hospitals, not-for-profit entities, as well as external commercial clients.

Spectrometers

Bruker maXis Impact

Ultra-High Resolution Quadrupole | Time-of-Flight | LC/MS/MS System
  • Sub-ppm mass accuracy and 40,000 Full-Sensitivity Resolution for complex, high-background matrices
  • Market-leading isotopic fidelity for definitive molecular formulae determination with Smart Formula and Smart Formula 3D
  • Extreme sensitivity across the entire mass range from very small molecules to intact proteins
  • Specialty software packages: BioTools, ProfileAnalysis, MetaboliteTools, TargetAnalysis
  • Electrospray Ionization Source (ESI Positive and Negative)
  • Agilent 1200 SL LC System

Bruker micrOTOF

Time-of-Flight | LC/MS System
  • Moderate mass accuracy and resolution
  • Routine molecular weight verification
  • Electrospray Ionization Source (ESI Positive and Negative)
  • Agilent 1200 SL LC System

Thermo Q-Exactive HF Orbitrap

nanoLC-MS/MS system for proteomics analysis
  • Q-Exactive HF is a Hybrid Quadrupole-Orbitrap Mass Spectrometer, equipped with an Ultrahigh-Field Orbitrap, which provides accurate and highly sensitive detection of peptides in complex biological samples
  • Easy nLC 1000 UHPLC delivers nanoliter per minute accurate and highly reproducible flow rate
  • Easy-Spray nanoESI source with reliable and reproducible ionization for the state-of-the-art performance of both expert and nonexpert users
  • High throughput (> 1000 proteins/h) and high sensitivity (attomole)
  • Discovery based shotgun proteomics and targeted PRM analysis
  • Accessible in Prof. B. Sun’s lab. Please contact bingyun_sun@sfu.ca for more info.

Sample Submission

The mass spectrometry facility's sample drop-off box is located just outside the entrance to the NMR and MS facility on the 6000 level of the Chemistry Department (Shrum Science Centre), near Science Stores.  The top and bottom compartments are for sample-drop off and pick-up, respectively.

Samples must be submitted with a completed sample submission form.

For samples that are not stable at room temperature, please contact Hongwen Chen to arrange special receiving.

Useful documents: a new sample submission form and a brief guide to Mass Spec Services.

Contact

Eric Ye

SUPERVISOR, NMR & MS SYSTEMS AND OPERATIONS

Office: C9039
Tel: 778-782-4464
Email: yegangy@sfu.ca

Hongwen Chen

Mass Spectrometry Specialist

Office: C6085
Tel: 778-782-7163
Email: hongwenc@sfu.ca

Please contact us to discuss our MS services.  Pricing is available on request.