Publications

A complete list of publications up to January 2012 is available here.

 

Recent Publications
  • Mohan, S.; Kerry, P. S.; Bance, N.; Niikura, M.; Pinto, B. M. (2013). Serendipitous Discovery of a Potent Influenza Virus A Neuraminidase Inhibitor. Angew. Chem. Int. Ed. doi: 10.1002/anie.201308142
  • Poulin, M. B.; Shi, Y.; Protsko, C.; Dalrymple, S. A.; Sanders, D. A. R.; Pinto, B. M.; Lowary, T. L. (2013). Specificity of a UDP-GalNAc Pyranose–Furanose Mutase. A Potential Drug Target for Campylobacter jejuni Infections. ChemBioChem. doi: 10.1002/cbic.201300653
  • Adabala, P. J. P.; LeGresley, E.; Bance, N.; Niikura, M.; Pinto, B. M.(2013). Exploitation of the Catalytic Site and 150 Cavity for Design of Neuraminidase Inhibitors. J. Org. Chem. doi: 10.1021/jo401854w
  • Auzanneau, F.-I.; Borrelli, S.; Pinto, B. M. (2013). Synthesis and Immunological Activity of an Oligosaccharide-conjugate as a Vaccine Candidate Against Group A Streptococcus . Bioorg. Med. Chem. Lett. doi: 10.1016/j.bmcl.2013.09.042
  • Kerry, P. S.; Mohan, S.; Russell, R. J.; Bance, N.; Niikura, M.; Pinto, B. M. (2013). Structural basis for a class of nanomolar influenza A neuraminidase inhibitors . Sci. Rep. doi: 10.1038/srep02871
  • Mohan, S.; Eskandari, R.; Pinto, B.M. (2013). Naturally Occurring Sulfonium-Ion Glucosidase Inhibitors and Their Derivatives: A Promising Class of Potential Antidiabetic Agents. Acc. Chem. Res . doi:10.1021/ar400132g
  • Gu, G.; Adabala, P. J. P.; Szczepina, M. G.; Borrelli, S.; Pinto, B.M. (2013). Synthesis and Immunological characterization of Modified Hyaluronic Acid Hexasaccharide Conjugates. J. Org. Chem . doi:10.1021/jo4012442
  • Greenway, K. T., LeGresley, E. B., Pinto, B.M. (2013). The Influence of 150-Cavity Binders on the Dynamics of Influenza A Neuraminidases as Revealed by Molecular Dynamics Simulations and Combined Clustering. PLoS ONE . doi:10.1371/journal.pone.0059873
  • Dahabieh, M.S., Samantha, D., Brodovitch, J.-C., Frech, C., O'Neill, M.A., Pinto, B.M. (2012). Sequence Dependent Structural Dynamics of Primate Adenosine-to-Inosine Editing Substrates. ChemBioChem. doi:10.1002/cbic.201200526

  • Zandberg, W., Kumarasamy, J., Pinto, B.M., Vocadlo, D. (2012). Metabolic Inhibition of Sialyl-LewisX Biosynthesis by 5-Thiofucose Remodels the CEll Surface and Impairs Selectin-Mediated Cell Adhesion. J. Biol. Chem. doi:10.1074/jbc.M112.403568

  • Greenway, K.T., Bischoff, A.L., Pinto, B.M. (2012). Hyperconjugation as Probed Experimentally with the Conformational Deuterium Isotope Effect. J. Org. Chem. doi:10.1021/jo3017988

  • Jones, K, Eskarandari, R., Jones, K., Reddy, R.K., Quezada-Valvillo R., Nichols, B., Rose, D.R., Hamaker, B., Pinto, B.M. (2012). Investigations of Structures and Properties of the Human Intestinal Enzymes MGAM and SI . J. Pediatr. Gastroenterol. Nutr. doi:10.1097/01.mpg.0000421403.34763.71

  • Yu, B.-H., Eskarandari, R., Jones, K., Reddy, R.K., Quezada-Calvillo, R., Nichols, B., Rose, D.R., Hamaker, B., Pinto, B.M. (2012). Modulation of Starch Digestion for Slow Glucose Release Through "Toggling" of Activities of Mucosal alpha-Glucosidases. J. Biol. Chem. doi:10.1074/jbc.M112.351858

  • Mohan, S., McAtamney S., Jaykanthan, J., Eskarandi, R., von Itzstein, M., Pinto, B.M. (2012). Antiviral activities of sulfonium-ion glucosidase inhibitors and 5-thiomannosylamine-disaccharide derivatives against dengue virus. Int. J. Antimicrob. Agents . doi:10.1016/j.ijantimicag.2012.05.002

  • Fernandez-Herrera, M.A, Lopez-Munoz, H, Hernandez-Cazquez, J.M.V, Sanchez-Sanchez, L., Escobar-Sanchez, M.L., Pinto, B.M., Sandoval-Ramirez, J.(2012). Synthesis and selective anticancer activity of steroidal glycoconjugates. Eur. J. Med. Chem. . doi:10.1016/j.ejmech.2012.06.027

  • Shi, Y., Pinto, B. M (2012). Molecular dynamics simulations of carbohydrate-mimetic haptens in complex with a complementary anti-carbohydrate antibody. Carbohydr. Res. doi:10.1016/j.carres.2012.05.024

  • Eskandari, R., K. Jones, D. R. Rose, B. M. Pinto (2011). Selectivity of 3'-O-Methylponkoranol for Inhibition of N- and C-terminal Maltase Glucoamylase and Sucrase Isomaltase, Therapeutic Targets for Digestive Disorders and Their Sequelae. Bioorg. Med. Chem. Lett.. doi:10.1016/j.bmcl.2011.08.069

  • Eskandari R, Jones K, Ravinder Reddy K, Jayakanthan K, Chaudet M, Rose DR, Pinto BM. (2011). Probing the Intestinal α-Glucosidase Enzyme Specificities of Starch-Digesting Maltase-Glucoamylase and Sucrase-Isomaltase: Synthesis and Inhibitory Properties of 3'- and 5'-Maltose-Extended De-O-sulfonated Ponkoranol. Chem. Eur. J . doi:10.1002/chem.201102109

  • Eskandari R, Jones K, Rose DR, Pinto BM. (2011). The effect of heteroatom substitution of sulfur for selenium in glucosidase inhibitors on intestinal α-glucosidase activities. Chem Commun (Camb). doi:10.1039/c1cc13052h

  • Szczepina, M.G., D.W. Bleile, B.M. Pinto (2011). Investigation of the Binding of a Carbohydrate-mimetic Peptide to its Complementary Anti-carbohydrate Antibody by STD-NMR Intensity-restrained CORCEMA Optimization (SICO) and Molecular Dynamics Simulations. Chem. Eur. J. doi:10.1002/chem.201100222

  • Eskandari R, Jones K, Rose DR, Pinto BM. (2011). Selectivity of 3'-O-methylponkoranol for inhibition of N- and C-terminal maltase glucoamylase and sucrase isomaltase, potential therapeutics for digestive disorders or their sequelae. Bioorg Med Chem Lett. doi:10.1016/j.bmcl.2011.08.069

  • Szczepina MG, Bleile DW, Pinto BM. (2011). WaterLOGSY NMR Experiments in Conjunction with Molecular-Dynamics Simulations Identify Immobilized Water Molecules That Bridge Peptide Mimic MDWNMHAA to Anticarbohydrate Antibody SYA/J6. Chem. Eur. J . doi:10.1002/chem.201101464

  • Albohy, A., S. Mohan, B.M. Pinto, C.W. Cairo (2011). The limited potency of oseltamivir analogs against human neuraminidases provides a strategy for improving the selectivity of influenza viral neuraminidase inhibitors. Bioorg. Med. Chem. doi:10.1016/j.bmc.2011.03.039

  • Zandberg, W.F., S. Benjannet, J. Hamelin, B. M. Pinto, N.G. Seidah (2011). N -glycosylation Controls Trafficking, Zymogen Activation, and Substrate Processing of Proprotein Convertases PC1/3 and SKI-1. Glycobiology. doi: 10.1093/glycob/cwr060

  • Niikura, M., N. Bance, S. Mohan, B.M. Pinto (2011). Replication Inhibition Activity of Carbocycles Related to Oseltamivir on Influenza A Virus in vitro. Antiviral Res. 90: 160-163. doi:10.1016/j.antiviral.2011.03.180

  • Fernández-Herrera, M.A., H. López-Muñoz, J. M. V. Hernández-Vázquez, M. López-Dávila, S. Mohan, M. L. Escobar-Sánchez, L. Sánchez-Sánchez, B. M. Pinto, J. Sandoval-Ramírez (2011). Synthesis of the steroidal glycoside (25R)-3β,16β-diacetoxy-12,22-dioxo-5α-cholestan-26-yl β-d-glucopyranoside and its anti-cancer properties on cervicouterine HeLa, CaSki, and ViBo cells. Eur. J. Med. Chem. doi:10.1016/j.ejmech.2010.07.051