Simon Fraser University
Engaging the World

Department of Chemistry

Research Papers

  1. Superhydrophobic substrates from off-the-shelf laboratory filter paper: simplified preparation, patterning, and assay application, Zhang, L.; Kwok, H.; Li, X.; Yu, H.-Z., ACS Appl. Mater. Interfaces, 2017;9(45):39728-39735.
  2. Integrated smartphone-app-chip system for on-site ppb-level colorimetric quantitation of aflatoxins, Li, X.; Yang, F.; Wong, J. X. H.; Yu, H.-Z. Anal. Chem. 2017;89(17):8908-8916.
  3. Plastic fingerprint replica: solvent-assisted 3D molding and motion-promoted nano-spherulite formation, Schultz, C. W.; Wong, J. X. H.; Yu, H-Z.; Can. J. Chem. 2017, in press (June 24, 2017; SFU special issue).
  4. A non-linear harmonic analysis of potential induced fluorescence modulation of a DNA self-assembled monolayer, Yu, Z. L.; Leung, K. K.; Yu, H.-Z.; Bizzotto, D. Electrochim. Acta 2017, 245, 386–394.
  5. Host-Guest Interaction at Molecular Interfaces: Binding of Cucurbit[7]uril on Ferrocenyl Self-Assembled Monolayers on Gold, Qi, L.; Tian, H.; Shao, H.; Yu, H.-Z., J. Phys. Chem. C 2017, 121, 7985–7992.
  6. Revealing and resolving the restrained enzymatic cleavage of DNA self-assembled monolayers on gold: electrochemical quantitation and ESI-MS confirmation, Gao, X.; Geng, M.; Li, Y.; Wang, X.; Yu, H.-Z., Anal. Chem. 2017, 89, 2464–2471.
  7. Digitized molecular detection on off-the-shelf Blu-ray discs: upgraded resolution and enhanced Sensitivity, Shi, M.; Weng, S.; Li, X.; Yu, H.-Z. Sens. Actuators B 2017, 242, 79–86.
  8. Optical disc technology-enabled analytical devices: from hardware modification to digitized molecular detection, Weng, S.; Li, X.; Li, Y.; Yu, H.-Z. Analyst 2016, 141, 6190-6201 (Tutorial Review, cover picture).
  9. Blu-ray Technology-Based Quantitative Assays for Cardiac Markers: From Disc Activation to Multiplex Detection, Weng, S.; Li, X.; Niu, M.; Ge, B.; Yu, H.-Z. Anal. Chem. 2016, 88, 6889–6896 (cover picture).
  10. Facile Preparation of Nanostructured, Superhydrophobic Filter Paper for Efficient Water/Oil Separation, Wang, J.; Wong, J.X.H.; Kwok, H.; Li, X.; Yu, H.-Z., PLoS ONE 2016, 11, e0151439(1-12).
  11. DNA-Redox Cation Interaction Improves the Sensitivity of an Electrochemical Immunosensor for Protein Detection, Li, P.; Ge, B.; Ou, L.M.-L.; Yao, Z.; Yu, H.-Z. Sensors 2015, 15, 20543-20556 (invited feature article).
  12. Direct Reading of bona fide barcode assays for diagnostics with smartphone apps, Wong, J. X. H.; Li, X.; Liu, F. S. F.; Yu, H.-Z. Sci. Rep. 2015, 5, 11727 (1-11).
  13. Smartphone-readable barcode assay for the detection and quantitation of pesticide residues, Guo, J.; Wong, J. X. H.; Li, X.; Cui, C.; Yu, H.-Z. Analyst 2015, 140, 5518 - 5525 (cover picture).
  14. Detection and quantitation of heavy metal ions on bona fide DVDs using DNA molecular beacon probes, Zhang, L.; Wong, J. X. H.; Li, X.; Li, Y.; Yu, H.-Z. Anal. Chem. 2015, 87, 5062–5067.
  15. Homogenized redox behavior of electroactive self-assembled monolayers on gold in the organic phase, Tian, H.; Qi, L.; Xiang, D.; Shao, H.; Yu, H.-Z. Electrochim. Acta 2015, 170, 369–375.
  16. On-site chip-based colorimetric quantitation of organophosphorus pesticides using an office scanner, Meng, X.; Schultz, C. W.; Cui, C.; Li, X.; Yu, H.-Z., Sen. Actuators B 2015, 215, 577-583.
  17. Binary DNA hairpin-based colorimetric biochip for simultaneous detection of Pb2+ and Hg2+ in real-world samples, Shi, X.; Gao, X.; Zhang, L.; Li, Y.; Fan, L.; Yu, H.-Z. Analyst 2015, 140, 2608–2612
  18. Metastable Molecular Metal-Semiconductor Junctions, Zhu, L.; Popoff, R. T. M.; Yu, H.-Z. J. Phys. Chem. C 2015, 119, 1826–1831.
  19. Indirect Competitive Assays on DVD for Direct Multiplex Detection of Drugs of Abuse in Oral Fluids, Zhang, L.; Li, X.; Li, Y.; Shi, X.; Yu, H.-Z. Anal. Chem. 2015, 87, 1896–1902.
  20. DNA mechatronic devices switched by K+ and by Sr2+ are structurally, topologically and electronically distinct, Huang, Y. C.; Yu, H.-Z.; Sen, D. Biopolymers 2015, 103, 460-468.
  21. Unique intramolecular electronic communications in mono-ferrocenylpyrimidine derivatives: correlation between redox properties and structural nature, Xiang, D.; Noel, J.; Shao, H.; Dupas, G.; Merbouh, N.; Yu, H.-Z. Electrochimi. Acta 2015, 162, 31-35.
  22. Comment on “Image-based ELISA on an activated polypropylene microtest plate - A spectrophotometer-free low cost assay technique” Wong, J. X.; Yu, H.-Z. Biosen. Bioelectron. 2015, 63, 602-604.
  23. Thin-film voltammetry and its analytical applications: A review, Tian, H.; Li, Y.; Shao, H.; Yu, H.-Z. Anal. Chim. Acta 2015, 855, 1-12 (Featured Review Article; cover picture).
  24. Mobile app-based quantitative scanometry, Wong, J. X. H.; Liu, F. S. F.; Yu, H.-Z. Anal. Chem. 2014, 86, 11966−11971.
  25. Synthesis and photo-sensing properties of Zn-ZnO core-shell nanofibers, Hsu, S.-H.; Chen, Y.-P.; Ye, C.-C.; Tseng, I.-L.; Chao, L.-C.; Yu, H.-Z. Sen. Actuators B 2014, 204,175–182.
  26. DNA molecular beacon-based plastic biochip: a versatile and sensitive scanometric detection platform, Shi, X.; Wen, J.; Zheng, Y.; Li, Y.; Zhou, J.; Li, X.; Yu, H.-Z. ACS Appl. Mater. Interface 2014, 6, 21788–21797.
  27. Electrochemical identification of molecular heterogeneity in binary redox self-assembled monolayers on gold, Tian, H.; Xiang, D.; Shao, H.; Yu, H.-Z. J. Phys. Chem. C 2014, 118, 13733–13742.
  28. DVD technology-based molecular diagnosis platform: quantitative pregnancy test on a disc, Li, X.; Weng, S.; Ge, B.; Yao, Z.; Yu, H.-Z., Lab Chip. 2014, 14, 1686–1694.
  29. DVD diagnostic software for reading disc-based bioassays, a comparative study, Zhao, X.; Li, X.; Cui, C.; Yu, H.-Z., Sen. Actuators B 2014, 195, 116–122.
  30. Functional DNA switches: rational design and electrochemical signaling, Tang, Y.; Ge, B.; Sen, D.; Yu, H.-Z., Chem. Soc. Rev. 2014, 43, 518–529.
  31. Selective dehybridization of DNA-Au nanoconjugates using laser irradiation, Asanuma, H.; Jiang, Z.; Ikeda, K.; Uosaki, K.; Yu, H.-Z. Phys. Chem. Chem. Phys. 2013, 15, 15995–16000.
  32. Preparation of transparent superhydrophobic glass slides: Demonstration of surface chemistry characteristics, Wong, J.X.; Yu, H.-Z., J. Chem. Ed. 2013, 90, 1203-1206.
  33. Facile fabrication of ZnO nanowire-based UV sensors by focused ion beam micromachining and thermal oxidation, Chao, L.-C.; Ye, C.-C.; Chen, Y.-P.; Yu, H.-Z., Appl. Surf. Sci. 2013, 282, 384–389.
  34. Controlled wetting on electrodeposited oxide thin films: from hydrophilic to superhydrophobic, Hao, Y.; Soolaman, D. M.; Yu, H.-Z., J. Phys. Chem. C 2013, 117, 7736–7743.
  35. Immobilization of redox-labeled hairpin DNA aptamers on gold: electrochemical quantitation of epithelial tumor marker mucin 1, Ma, F.; Ho, C.; Cheng, A. K. H.; Yu, H.-Z. Electrochimi. Acta 2013, 110, 139-145 (2012 ISE meeting special issue).
  36. Reading Disc-Based Bioassays with Standard Computer Drives, Yu, H.-Z.; Li, Y.; Ou, L.M.L. Acc. Chem. Resc. 2013, 46, 258–268.
  37. Simple and reproducible method of preparing transparent superhydrophobic glass, Wong, J.X.H.; Asanuma, H.; Yu, H.-Z. Thin Solid Films, 2012, 522, 159-163
  38. A mechano-electronic DNA switch, Thomas, J. M.; Yu, H.-Z.; Sen, D., J. Am. Chem. Soc. 2012, 134, 13738-13748.
  39. Analyte-driven switching of DNA charge transport: de novo creation of electronic sensors for an early lung cancer biomarker, Thomas, J. M.; Chakraborty, B.; Sen, D.; Yu, H.-Z. J. Am. Chem. Soc. 2012, 134, 13823-13833.
  40. Reduction of gold penetration through phenyl-terminated alkyl monolayers on silicon, Popoff, R. T. W.; Zavareh, A. Kavanagh, K. K.; Yu, H.-Z., J. Phys. Chem. C 2012, 116, 17040–17047.
  41. Adenosine-triggered elimination of methylene blue noncovalently bound to immobilized functional dsDNA-aptamer constructs, Dai, Y.; Chakraborty, B.; Ge, B.; Yu, H.-Z. J. Phys. Chem. B 2012, 116, 6361-6368.
  42. A USB-based electrochemical biosensor prototype for point-of-care diagnosis, Loncaric, C.; Tang, Y.; Ho, C.; Parameswaran, M.; Yu, H.-Z. Sens. Actuators B 2012, 161, 908-913.
  43. Investigation of liquid-liquid interfacial electron transfer kinetics using multicenter ferrocenyl complexes, Xiang, D.; Merbouh, N.; Shao, H.; Yu, H.-Z. Electrochim. Acta 2011, 56, 5788-5793.
  44. Formation kinetics and stability of phosphonate self-assembled monolayers on indium tin oxide, Jo, K.; Yu, H.-Z.; Yang, H.; Electrochimi. Acta 2011, 56, 4828-4833.
  45. Computer-readable DNAzyme assay on disc for ppb-level lead detection, Wang, H.; Ou, L. M. L.; Suo, Y.; Yu, H.-Z. Anal. Chem. 2011, 83, 1557-1563.
  46. Preparation of ideal molecular junctions: depositing non-invasive gold contacts on molecularly-modified silicon, Popoff, R. T. W.; Kavanagh, K. K.; Yu, H.-Z., Nanoscale 2011, 3, 1434-1445 (invited review).
  47. A robust electronic switch made of immobilized duplex/quadruplex DNA, Ge, B.; Huang, Y. C.; Sen, D.; Yu, H.-Z. Angew. Chem. Int. Ed. 2010, 49, 9965-9967.
  48. Software-based quantitation of bioassays-on-CD, Pallapa, M.; Ou, L. M. L.; Parameswaran, M.; Yu, H.-Z., Sens. Actuators B 2010, 148, 620–623.
  49. Long-term stability and electrical performance of organic monolayers on hydrogen-terminated silicon, Popoff, R. T. W.; Asanuma, H.; Yu, H. Z.; J. Phys. Chem. C 2010, 114, 10866–10872.
  50. Redox behavior and ion-pairing thermodynamics of ferrocene and its derivatives in the organic phase, Xiang, D.; Gao, G.; Shao, H.; Li, H.; Zhang, H.-L.; Yu, H.-Z., J. Phys. Chem. C 2010, 114, 617–621.
  51. Water structure at superhydrophobic quartz / water interfaces: a vibrational sum frequency generation spectroscopy study, Asanuma, H.; Noguchi, H.; Uosaki, K.; Yu, H.-Z., J. Phys. Chem. C 2009, 113, 21155-21161.
  52. Probing the molecular conformation of self-assembled monolayers at metal/semiconductor interfaces by vibrational sum frequency generation spectroscopy, Asanuma, H.; Noguchi, H.; Huang, Y.; Uosaki, K.; Yu, H.-Z., J. Phys. Chem. C 2009, 113, 21139-21146.
  53. Design and testing of aptamer-based electrochemical biosensors for small molecules and proteins, Cheng, A. K. H.; Sen, D.; Yu, H.-Z., Bioelectrochemistry 2009, 77, 1-12 (invited review).
  54. Rational design and performance testing of aptamer-based electrochemical biosensors for adenosine, Chakraborty, B.; Jiang, Z.; Li, Y.; Yu, H.-Z., J. Electroanal. Chem. 2009, 635, 75-82.
  55. Aptamer-based detection of epithelial tumor marker mucin 1 with quantum dot-based fluorescence readout, Cheng, A. K. H.; Su, H.; Wang, Y. A.; Yu, H.-Z., Anal. Chem. 2009, 81, 6130-6139.
  56. The charge conduction properties of a parallel-stranded DNA G-quadruplex: implications for chromosomal oxidative damage, Huang, Y.-C.; Cheng, A. K. H.; Yu, H.-Z.; Sen, D. Biochemistry, 2009, 48, 6794–6804.
  57. On the nature of DNA Self-Assembled Monolayers on Au: measuring surface heterogeneity with electrochemical in situ fluorescence microscopy, Murphy, J. N.; Cheng, A. K. H.; Yu, H. Z.; Bizzotto, D., J. Am. Chem. Soc. 2009, 131, 4042-4050.
  58. Inkjet printed electrode arrays for potential modulation of DNA self-assembled monolayers on gold, Li, Y. C.; Li, P. C. H.; Parameswaran, M.; Yu, H. Z., Anal. Chem. 2008, 80, 8814-8821.
  59. Digitized molecular diagnostics: Reading disc-based bioassays with standard computer drives, Li, Y. C.; Ou, L. M. L.; Yu, H. Z., Anal. Chem. 2008, 80, 8216-8223.
  60. Polymorphism of Zn[Au(CN)2]2 and its luminescent sensory response to NH3 vapor, Katz, M.; Ramnial, T.; Yu, H. Z.; Leznoff, D. B., J. Am. Chem. Soc. 2008, 130, 10662-10673.
  61. Thin-layer electrochemistry of ferrocenylbenzene derivatives: intramolecular electronic communication, Wang, M. C. P.; Li, Y.-C.; Merbouh, N.; Yu, H. Z.,Electrochimi. Acta. 2008, 53, 7720-7725.
  62. Immobilized DNA switches as electronic sensors for picomolar detection of plasma proteins, Huang, Y. C.; Ge, B.; Sen, D.; Yu, H. Z., J. Am. Chem. Soc. 2008, 130, 8023-8029.
  63. Metal cation-induced deformation of DNA self-assembled monolayers on silicon, Asanuma, H.; Noguchi, H.; Uosaki, K.; Yu, H. Z., J. Am. Chem. Soc. 2008, 130, 8016-8022.
  64. Nanoscale electrical and structural characterization of gold/molecular-monolayer/silicon junctions, Kuikka, M. A.; Li, W.; Kavanagh, K. L.; Yu, H. Z., J. Phys. Chem. C 2008, 112, 9081-9088.
  65. Fungal pathogenic nucleic acid detection achieved with a microfluidic microarray device, Wang, L.; Li, P. C. H.; Yu, H. Z.; Parameswaran, M., Anal. Chim. Acta 2008, 610, 97-104.
  66. Monolayer-directed electrodeposition of oxide thin films: surface morphology versus chemical modification, Soolaman, D. M.; Yu, H. Z., J. Phys. Chem. C 2007, 111, 14157-14164.
  67. Spiral microchannels on a CD for DNA hybridizations, Peng, X. Y.; Li, P. C. H.; Yu, H. Z.; Parameswaran, M.; Chou, W. L., Sens. Actuators. B 2007, 128, 64-69.
  68. "Non-evaporating" microdroplets on self-assembled monolayer surfaces under ambient conditions, Cheng, A. K. H.; Soolaman, D. M.; Yu, H. Z., J. Phys. Chem. B 2007, 111, 7561-7566.
  69. Label-free voltammetric detection of lysozyme with aptamer-modified gold electrodes, Cheng, A. K. H.; Ge, B. X.; Yu, H. Z., Anal. Chem. 2007, 79, 5158-5164.
  70. Fabrication of microsensors using unmodified office inkjet printers, Cho, H.; Parameswaran, M.; Yu, H. Z. Sens. Actuators. B 2007, 123, 749-756
  71. Electrochemical investigation of DNA-modified surfaces: From quantitation methods to experimental conditions, Ge, B.; Huang, Y.-C.; Sen, D.; Yu, H. Z. J. Electroanal. Chem. 2007, 602, 156-162
  72. DNA detection on plastic: Surface activation protocol to convert polycarbonate substrates to biochip platforms, Li, Y. C.; Wang, Z.; Ou, L. M. L.; Yu, H. Z. Anal. Chem. 2007, 79, 426-433.
  73. Electrochemical impedance and solid-state electrical characterization of silicon (111) modified with ω-functionalized alkyl monolayers, Asanuma, H.; Bishop, E. M.; Yu, H. Z. Electrochimi. Acta 2007, 52, 2913-2919.
  74. Evaporation of microdroplets of ethanol-water mixtures on gold surfaces modified with self-assembled monolayers, Cheng, A. K. H.; Soolaman, D. M.; Yu, H. Z. J. Phys. Chem. B 2006, 110, 11267-11271.
  75. Thin-layer electrochemistry of 1,3,5-triferrocenylbenzene: a unique two-step, three electron process, Li, Y. C.; Tsang, E. M. Y.; Chan, A. Y. C.; Yu, H. Z. Electrochem. Commun. 2006, 8, 951-955.
  76. Structure and reactivity of alkoxycarbonyl (ester)-terminated monolayers on silicon: sum-frequency generation spectroscopy, Asanuma, H.; Noguchi, H.; Uosaki, K.; Yu, H. Z. J. Phys. Chem. B 2006, 110, 4892-4899.
  77. Voltammetric study of the ion-exchange binding of non-electroactive metal cations to DNA-modified surfaces, Su, L.; Sen, D.; Yu, H. Z. Analyst 2006, 131, 317-322.
  78. Water microdroplets on molecularly tailored surfaces: correlation between wetting hysteresis and evaporation mode switching, Soolaman, D. M.; Yu, H. Z. J. Phys. Chem. B 2005, 109, 17967-17973.
  79. Kinetic control of the photochemical reactivity of hydrogen terminated silicon with bifunctional molecules, Asanuma, H.; Lopinski, G. P.; Yu, H. Z. Langmuir 2005, 21, 5013-5018.
  80. Versatile Portable device for solid-state electrical measurements of 'soft' materials, Asanuma, H.; Liu, Y. J.; Yu, H. Z. Jpn. J. Appl. Phys. 2005, 41, 1991-1993.
  81. Analytical/materials chemistry on old CDs: beyond self-assembly, Ho, C.; Soolaman, D. M.; Yu, H. Z. Can. J. Chem. 2005, 83, 403-412.
  82. Bioreactive surfaces prepared via self-assembly of dendron thiols and subsequent dendrimer bridging reactions, Yang, M.; Tsang, E. M. Y.; Wang, Y. A.; Peng, X. G.; Yu, H. Z. Langmuir 2005, 21, 1858-1865.
  83. New chemistry on old CDs, Yu, H. Z. Chem. Commun. 2004, 2633-2636.
  84. Kinetics of ion-exchange binding of redox metal cations to thiolate-DNA monolayers on gold, Su, L.; Sankar, C. G.; Sen, D.; Yu, H. Z. Anal. Chem. 2004, 76, 5953-5959.
  85. m-Terphenyl thiols: rigid and bulky molecules for the formation of bioactive self-assembled monolayers on gold, Dickie, D. A.; Chan, A. Y. C.; Jalali, H.; Jenkins, H. A.; Yu, H. Z.; Clyburne, J. A. C. Chem. Commun. 2004, 2432-2433.
  86. Evaporation of water microdroplets on self-assembled monolayers: From pinning to shrinking, Yu, H. Z.; Soolaman, D. M.; Rowe, A. W.; Banks, J. T. ChemPhysChem (Eur. J.) 2004, 5, 1035-1038.
  87. Structure and reactivity of mixed ω-carboxyalkyl / alkyl monolayers on silicon: ATR-FTIR spectroscopy and contact angle titration, Liu, Y. J.; Navasero, N. M.; Yu, H. Z. Langmuir 2004, 20, 4039-4050.
  88. Thin-layer electrochemistry of 1,3-diferrocenyl-2-buten-1-one: Direct correlation between driving force and liquid/liquid interfacial electron transfer rates, Xu, J.; Frcic, A.; Clyburne, J. A. C.; Gossage, R. A.; Yu, H. Z. J. Phys. Chem. B 2004, 108, 5742-5746.
  89. Effect of organic contamination on the electrical degradation of hydrogen-terminated silicon upon exposure to air under ambient conditions, Liu, Y. J.; Yu, H. Z. J. Electrochem. Soc. 2003, 150, G861-G865.
  90. Molecular passivation of classical mercury-silicon (p-type) diode junctions: alkylation, oxidation, and alkylsilation, Liu, Y. J.; Yu, H. Z. J. Phys. Chem. B 2003, 107, 7803-7811.
  91. Voltammetric procedure for examining DNA-modified surfaces: quantitation, cationic binding activity, and electron transfer, Yu, H. Z.; Luo, C. Y.; Sankar, C. G.; Sen, D. Anal. Chem. 2003, 75, 3902-3907.
  92. Alkyl monolayer passivated metal-semiconductor diodes: 2. Comparison with native silicon oxide, Liu, Y. J.; Yu, H. Z. ChemPhysChem. 2003, 4, 335-342.
  93. Impact of organic contamination on the electrical properties of hydrogen-terminated silicon under ambient conditions, Liu, Y. J.; Waugh, D. M.; Yu, H. Z. Appl. Phys. Lett., 2002, 81, 4967-4969.
  94. Templated electrochemical deposition of zirconia thin films on recordable CDs, Yu, H. Z.; Rowe, A. W.; Waugh, D. M. Anal. Chem. 2002, 74, 5742-5747.
  95. Alkyl monolayer passivated metal-semiconductor diodes: Molecular tunability and electron transport, Liu, Y. J.; Yu, H. Z. ChemPhysChem. 2002, 3, 799-802.
  96. Direct visualization of the hydrolysis kinetics of titanium (IV) alkoxides on functionalized gold surfaces, Banks, J. T.; Yu, T. T.; Yu, H. Z. J. Phys. Chem. B 2002, 106, 3538-3542.
  97. Self-assembly on recordable CDs, Yu, H. Z. Anal. Chem. 2001, 73, 4343-4347.