Clinical Trial for Treatment of Pain

The FREQ Procedure

Frequency
Percent
Row Pct
Col Pct

Table of Dose by Adverse
Dose Adverse Total
No Yes
0 26
16.15
81.25
25.49		 6
3.73
18.75
10.17		 32
19.88
 
 
1 26
16.15
78.79
25.49		 7
4.35
21.21
11.86		 33
20.50
 
 
2 23
14.29
71.88
22.55		 9
5.59
28.13
15.25		 32
19.88
 
 
3 18
11.18
56.25
17.65		 14
8.70
43.75
23.73		 32
19.88
 
 
4 9
5.59
28.13
8.82		 23
14.29
71.88
38.98		 32
19.88
 
 
Total 102
63.35		 59
36.65		 161
100.00

Statistics for Table of Dose by Adverse

Statistic Value ASE 95%
Confidence Limits
Gamma 0.5313 0.0935 0.3480 0.7146
Kendall's Tau-b 0.3373 0.0642 0.2114 0.4631
Stuart's Tau-c 0.4111 0.0798 0.2547 0.5675
Somers' D C|R 0.2569 0.0499 0.1592 0.3547
Somers' D R|C 0.4427 0.0837 0.2786 0.6068
Pearson Correlation 0.3776 0.0714 0.2378 0.5175
Spearman Correlation 0.3771 0.0718 0.2363 0.5178
Lambda Asymmetric C|R 0.2373 0.0837 0.0732 0.4014
Lambda Asymmetric R|C 0.1250 0.0662 0.0000 0.2547
Lambda Symmetric 0.1604 0.0621 0.0388 0.2821
Uncertainty Coefficient C|R 0.1261 0.0467 0.0346 0.2175
Uncertainty Coefficient R|C 0.0515 0.0191 0.0140 0.0890
Uncertainty Coefficient Symmetric 0.0731 0.0271 0.0199 0.1262

Somers' D C|R
Somers' D C|R 0.2569
ASE 0.0499
95% Lower Conf Limit 0.1592
95% Upper Conf Limit 0.3547

Test of H0: Somers' D C|R = 0
ASE under H0 0.0499
Z 5.1511
One-sided Pr > Z <.0001
Two-sided Pr > |Z| <.0001

Cochran-Armitage Trend Test
Statistic (Z) -4.7918
   
Asymptotic Test  
One-sided Pr < Z <.0001
Two-sided Pr > |Z| <.0001
   
Exact Test  
One-sided Pr <= Z 7.237E-07
Two-sided Pr >= |Z| 1.324E-06

Sample Size = 161