##Ngenes: 13656 Nprom: 96 ##GOterm total hits pval process GO:0006082 394 13 4.1268e-06 biological_process organic acid metabolism GO:0019752 394 13 4.1268e-06 biological_process carboxylic acid metabolism GO:0006120 36 5 6.3744e-06 biological_process mitochondrial electron transport, NADH to ubiquinone GO:0050875 6312 66 6.8950e-06 biological_process cellular physiological process GO:0007582 6940 70 8.3246e-06 biological_process physiological process GO:0008152 5111 57 1.0607e-05 biological_process metabolism GO:0006091 509 14 1.3392e-05 biological_process generation of precursor metabolites and energy GO:0009058 911 19 1.7245e-05 biological_process biosynthesis GO:0044237 4680 53 2.1078e-05 biological_process cellular metabolism GO:0008150 8219 76 6.0799e-05 biological_process biological_process GO:0009987 6819 67 6.2766e-05 biological_process cellular process GO:0044249 842 17 7.6490e-05 biological_process cellular biosynthesis GO:0042775 62 5 8.3656e-05 biological_process ATP synthesis coupled electron transport (sensu Eukaryota) GO:0042773 63 5 9.0124e-05 biological_process ATP synthesis coupled electron transport GO:0048598 109 0 1.0000e+00 biological_process embryonic morphogenesis GO:0030554 703 7 2.2526e-01 molecular_function adenyl nucleotide binding 1 1 1 1 1 1 1 GO:0051656 30 0 1.0000e+00 biological_process establishment of organelle localization GO:0007626 74 0 1.0000e+00 biological_process locomotory behavior GO:0007623 37 0 1.0000e+00 biological_process circadian rhythm GO:0006629 493 9 8.0151e-03 biological_process lipid metabolism 1 1 1 1 1 1 1 1 1 GO:0006626 36 0 1.0000e+00 biological_process protein targeting to mitochondrion GO:0008361 35 1 2.1836e-01 biological_process regulation of cell size 1 GO:0046467 31 1 1.9601e-01 biological_process membrane lipid biosynthesis 1 GO:0008360 87 0 1.0000e+00 biological_process regulation of cell shape GO:0006974 121 1 5.7446e-01 biological_process response to DNA damage stimulus 1 GO:0004197 83 0 1.0000e+00 molecular_function cysteine-type endopeptidase activity GO:0045449 847 3 9.4161e-01 biological_process regulation of transcription 1 1 1 GO:0051276 174 0 1.0000e+00 biological_process chromosome organization and biogenesis GO:0007369 59 0 1.0000e+00 biological_process gastrulation GO:0050953 80 0 1.0000e+00 biological_process sensory perception of light stimulus GO:0043231 2347 24 3.3501e-02 cellular_component intracellular membrane-bound organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0004806 37 0 1.0000e+00 molecular_function triacylglycerol lipase activity GO:0006367 85 0 1.0000e+00 biological_process transcription initiation from RNA polymerase II promoter GO:0006366 694 2 9.5892e-01 biological_process transcription from RNA polymerase II promoter 1 1 GO:0016705 66 0 1.0000e+00 molecular_function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0004857 128 0 1.0000e+00 molecular_function enzyme inhibitor activity GO:0009056 330 8 2.3404e-03 biological_process catabolism 1 1 1 1 1 1 1 1 GO:0009057 192 3 1.5339e-01 biological_process macromolecule catabolism 1 1 1 GO:0048568 35 0 1.0000e+00 biological_process embryonic organ development GO:0009055 54 6 2.6136e-06 molecular_function electron carrier activity 1 1 1 1 1 1 GO:0005102 284 5 5.0444e-02 molecular_function receptor binding 1 1 1 1 1 GO:0009108 94 2 1.4190e-01 biological_process coenzyme biosynthesis 1 1 GO:0009109 49 3 5.1483e-03 biological_process coenzyme catabolism 1 1 1 GO:0009100 88 2 1.2766e-01 biological_process glycoprotein metabolism 1 1 GO:0009101 85 1 4.5086e-01 biological_process glycoprotein biosynthesis 1 GO:0001738 58 0 1.0000e+00 biological_process morphogenesis of a polarized epithelium GO:0042165 69 0 1.0000e+00 molecular_function neurotransmitter binding GO:0001736 46 0 1.0000e+00 biological_process establishment of planar polarity GO:0048037 39 1 2.4009e-01 molecular_function cofactor binding 1 GO:0019953 472 2 8.4845e-01 biological_process sexual reproduction 1 1 GO:0016192 306 3 3.6461e-01 biological_process vesicle-mediated transport 1 1 1 GO:0003674 8432 76 1.9884e-04 molecular_function molecular_function 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0003676 1776 15 2.6279e-01 molecular_function nucleic acid binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0003677 844 3 9.4066e-01 molecular_function DNA binding 1 1 1 GO:0003678 51 0 1.0000e+00 molecular_function DNA helicase activity GO:0051327 94 1 4.8474e-01 biological_process M phase of meiotic cell cycle 1 GO:0005737 1511 27 3.5795e-06 cellular_component cytoplasm 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0005730 58 0 1.0000e+00 cellular_component nucleolus GO:0005739 468 19 6.4554e-10 cellular_component mitochondrion 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0006644 76 1 4.1478e-01 biological_process phospholipid metabolism 1 GO:0006643 87 1 4.5858e-01 biological_process membrane lipid metabolism 1 GO:0030594 69 0 1.0000e+00 molecular_function neurotransmitter receptor activity GO:0008757 61 0 1.0000e+00 molecular_function S-adenosylmethionine-dependent methyltransferase activity GO:0006915 179 0 1.0000e+00 biological_process apoptosis GO:0007349 30 0 1.0000e+00 biological_process cellularization GO:0017038 56 1 3.2597e-01 biological_process protein import 1 GO:0006120 36 5 6.3744e-06 biological_process mitochondrial electron transport, NADH to ubiquinone 1 1 1 1 1 GO:0004872 586 1 9.8516e-01 molecular_function receptor activity 1 GO:0004871 1090 7 6.5289e-01 molecular_function signal transducer activity 1 1 1 1 1 1 1 GO:0007582 6940 70 8.3246e-06 biological_process physiological process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0005694 214 0 1.0000e+00 cellular_component chromosome GO:0004252 262 0 1.0000e+00 molecular_function serine-type endopeptidase activity GO:0051049 62 1 3.5393e-01 biological_process regulation of transport 1 GO:0048468 355 1 9.2023e-01 biological_process cell development 1 GO:0001754 78 0 1.0000e+00 biological_process eye photoreceptor cell differentiation GO:0001751 75 0 1.0000e+00 biological_process eye photoreceptor cell differentiation (sensu Endopterygota) GO:0001752 35 0 1.0000e+00 biological_process eye photoreceptor fate commitment (sensu Endopterygota) GO:0016818 556 3 7.5426e-01 molecular_function hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1 1 1 GO:0016810 91 4 4.0267e-03 molecular_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1 1 1 1 GO:0016811 53 3 6.3851e-03 molecular_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1 1 1 GO:0016817 556 3 7.5426e-01 molecular_function hydrolase activity, acting on acid anhydrides 1 1 1 GO:0048110 57 0 1.0000e+00 biological_process oocyte construction (sensu Insecta) GO:0051189 60 0 1.0000e+00 biological_process prosthetic group metabolism GO:0048111 56 0 1.0000e+00 biological_process oocyte axis determination (sensu Insecta) GO:0008565 76 0 1.0000e+00 molecular_function protein transporter activity GO:0007601 80 0 1.0000e+00 biological_process visual perception GO:0043412 892 7 4.3851e-01 biological_process biopolymer modification 1 1 1 1 1 1 1 GO:0007600 266 0 1.0000e+00 biological_process sensory perception GO:0009966 106 1 5.2672e-01 biological_process regulation of signal transduction 1 GO:0007602 32 0 1.0000e+00 biological_process phototransduction GO:0050877 636 1 9.8973e-01 biological_process neurophysiological process 1 GO:0050874 930 4 8.9896e-01 biological_process organismal physiological process 1 1 1 1 GO:0035282 128 0 1.0000e+00 biological_process segmentation GO:0006936 93 0 1.0000e+00 biological_process muscle contraction GO:0000790 49 0 1.0000e+00 cellular_component nuclear chromatin GO:0051187 50 3 5.4426e-03 biological_process cofactor catabolism 1 1 1 GO:0051186 254 8 4.4446e-04 biological_process cofactor metabolism 1 1 1 1 1 1 1 1 GO:0019098 59 1 3.4010e-01 biological_process reproductive behavior 1 GO:0019094 38 0 1.0000e+00 biological_process pole plasm mRNA localization GO:0051234 2068 24 7.9624e-03 biological_process establishment of localization 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0007224 32 0 1.0000e+00 biological_process smoothened signaling pathway GO:0019899 55 0 1.0000e+00 molecular_function enzyme binding GO:0019898 45 0 1.0000e+00 cellular_component extrinsic to membrane GO:0044271 85 3 2.2443e-02 biological_process nitrogen compound biosynthesis 1 1 1 GO:0007420 49 0 1.0000e+00 biological_process brain development GO:0006325 139 0 1.0000e+00 biological_process establishment and/or maintenance of chromatin architecture GO:0006323 139 0 1.0000e+00 biological_process DNA packaging GO:0048518 207 0 1.0000e+00 biological_process positive regulation of biological process GO:0005996 101 0 1.0000e+00 biological_process monosaccharide metabolism GO:0009141 71 1 3.9373e-01 biological_process nucleoside triphosphate metabolism 1 GO:0009142 69 1 3.8510e-01 biological_process nucleoside triphosphate biosynthesis 1 GO:0006810 1832 22 7.6768e-03 biological_process transport 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0006865 46 1 2.7669e-01 biological_process amino acid transport 1 GO:0008094 38 0 1.0000e+00 molecular_function DNA-dependent ATPase activity GO:0008092 248 3 2.5364e-01 molecular_function cytoskeletal protein binding 1 1 1 GO:0016835 62 3 9.7699e-03 molecular_function carbon-oxygen lyase activity 1 1 1 GO:0016836 56 3 7.4192e-03 molecular_function hydro-lyase activity 1 1 1 GO:0016831 34 1 2.1283e-01 molecular_function carboxy-lyase activity 1 GO:0008233 668 1 9.9189e-01 molecular_function peptidase activity 1 GO:0003954 37 5 7.2700e-06 molecular_function NADH dehydrogenase activity 1 1 1 1 1 GO:0008237 192 1 7.4316e-01 molecular_function metallopeptidase activity 1 GO:0008236 298 0 1.0000e+00 molecular_function serine-type peptidase activity GO:0046903 238 3 2.3493e-01 biological_process secretion 1 1 1 GO:0016485 30 0 1.0000e+00 biological_process protein processing GO:0016481 115 0 1.0000e+00 biological_process negative regulation of transcription GO:0015020 35 1 2.1836e-01 molecular_function glucuronosyltransferase activity 1 GO:0051726 200 4 5.3064e-02 biological_process regulation of cell cycle 1 1 1 1 GO:0030162 30 0 1.0000e+00 biological_process regulation of proteolysis GO:0030163 90 2 1.3237e-01 biological_process protein catabolism 1 1 GO:0043038 62 2 7.1052e-02 biological_process amino acid activation 1 1 GO:0043039 61 2 6.9084e-02 biological_process tRNA aminoacylation 1 1 GO:0005083 95 4 4.6824e-03 molecular_function small GTPase regulator activity 1 1 1 1 GO:0005085 61 2 6.9084e-02 molecular_function guanyl-nucleotide exchange factor activity 1 1 GO:0000226 94 0 1.0000e+00 biological_process microtubule cytoskeleton organization and biogenesis GO:0000228 73 0 1.0000e+00 cellular_component nuclear chromosome GO:0004930 273 0 1.0000e+00 molecular_function G-protein coupled receptor activity GO:0007242 546 4 5.3780e-01 biological_process intracellular signaling cascade 1 1 1 1 GO:0007300 32 0 1.0000e+00 biological_process nurse cell to oocyte transport (sensu Insecta) GO:0007304 55 0 1.0000e+00 biological_process eggshell formation (sensu Insecta) GO:0007306 42 0 1.0000e+00 biological_process insect chorion formation GO:0007308 83 0 1.0000e+00 biological_process oocyte construction GO:0007309 80 0 1.0000e+00 biological_process oocyte axis determination GO:0031226 203 1 7.6255e-01 cellular_component intrinsic to plasma membrane 1 GO:0051169 67 1 3.7635e-01 biological_process nuclear transport 1 GO:0048102 72 0 1.0000e+00 biological_process autophagic cell death GO:0005654 205 0 1.0000e+00 cellular_component nucleoplasm GO:0017076 866 9 1.5521e-01 molecular_function purine nucleotide binding 1 1 1 1 1 1 1 1 1 GO:0050790 37 0 1.0000e+00 biological_process regulation of enzyme activity GO:0009308 379 9 1.4418e-03 biological_process amine metabolism 1 1 1 1 1 1 1 1 1 GO:0009309 85 3 2.2443e-02 biological_process amine biosynthesis 1 1 1 GO:0000003 518 3 7.1004e-01 biological_process reproduction 1 1 1 GO:0007498 207 1 7.6923e-01 biological_process mesoderm development 1 GO:0009199 69 1 3.8510e-01 biological_process ribonucleoside triphosphate metabolism 1 GO:0016853 91 1 4.7369e-01 molecular_function isomerase activity 1 GO:0008219 252 0 1.0000e+00 biological_process cell death GO:0016614 120 2 2.0670e-01 molecular_function oxidoreductase activity, acting on CH-OH group of donors 1 1 GO:0030695 137 4 1.6227e-02 molecular_function GTPase regulator activity 1 1 1 1 GO:0016616 85 2 1.2068e-01 molecular_function oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1 1 GO:0016209 37 0 1.0000e+00 molecular_function antioxidant activity GO:0051707 132 1 6.0641e-01 biological_process response to other organism 1 GO:0051705 56 1 3.2597e-01 biological_process behavioral interaction between organisms 1 GO:0051704 59 1 3.4010e-01 biological_process interaction between organisms 1 GO:0042995 30 0 1.0000e+00 cellular_component cell projection GO:0002165 351 3 4.4939e-01 biological_process larval or pupal development (sensu Insecta) 1 1 1 GO:0002164 45 1 2.7157e-01 biological_process larval development 1 GO:0006807 394 10 4.6991e-04 biological_process nitrogen compound metabolism 1 1 1 1 1 1 1 1 1 1 GO:0006800 67 0 1.0000e+00 biological_process oxygen and reactive oxygen species metabolism GO:0006512 191 3 1.5173e-01 biological_process ubiquitin cycle 1 1 1 GO:0006511 75 0 1.0000e+00 biological_process ubiquitin-dependent protein catabolism GO:0006519 295 9 2.4461e-04 biological_process amino acid and derivative metabolism 1 1 1 1 1 1 1 1 1 GO:0003743 56 0 1.0000e+00 molecular_function translation initiation factor activity GO:0005351 40 0 1.0000e+00 molecular_function sugar porter activity GO:0015144 81 1 4.3511e-01 molecular_function carbohydrate transporter activity 1 GO:0048522 185 0 1.0000e+00 biological_process positive regulation of cellular process GO:0004004 40 0 1.0000e+00 molecular_function ATP-dependent RNA helicase activity GO:0007269 110 1 5.3995e-01 biological_process neurotransmitter secretion 1 GO:0007268 233 1 8.0835e-01 biological_process synaptic transmission 1 GO:0007267 463 1 9.6353e-01 biological_process cell-cell signaling 1 GO:0007264 119 0 1.0000e+00 biological_process small GTPase mediated signal transduction GO:0006886 518 4 4.9618e-01 biological_process intracellular protein transport 1 1 1 1 GO:0031224 972 3 9.7067e-01 cellular_component intrinsic to membrane 1 1 1 GO:0018988 35 0 1.0000e+00 biological_process molting cycle (sensu Protostomia and Nematoda) GO:0016055 58 0 1.0000e+00 biological_process Wnt receptor signaling pathway GO:0016052 68 1 3.8074e-01 biological_process carbohydrate catabolism 1 GO:0016053 31 0 1.0000e+00 biological_process organic acid biosynthesis GO:0016051 50 0 1.0000e+00 biological_process carbohydrate biosynthesis GO:0043229 2736 26 5.8806e-02 cellular_component intracellular organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0043227 2349 24 3.3801e-02 cellular_component membrane-bound organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0043226 2737 26 5.9025e-02 cellular_component organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0048731 653 2 9.4726e-01 biological_process system development 1 1 GO:0031980 148 6 6.5357e-04 cellular_component mitochondrial lumen 1 1 1 1 1 1 GO:0042775 62 5 8.3656e-05 biological_process ATP synthesis coupled electron transport (sensu Eukaryota) 1 1 1 1 1 GO:0048736 136 1 6.1743e-01 biological_process appendage development 1 GO:0048737 133 1 6.0920e-01 biological_process appendage development (sensu Endopterygota) 1 GO:0015837 46 1 2.7669e-01 biological_process amine transport 1 GO:0005634 1565 3 9.9924e-01 cellular_component nucleus 1 1 1 GO:0005635 65 0 1.0000e+00 cellular_component nuclear envelope GO:0009987 6819 67 6.2766e-05 biological_process cellular process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0045132 37 0 1.0000e+00 biological_process meiotic chromosome segregation GO:0005184 33 0 1.0000e+00 molecular_function neuropeptide hormone activity GO:0009187 37 0 1.0000e+00 biological_process cyclic nucleotide metabolism GO:0005792 83 0 1.0000e+00 cellular_component microsome GO:0000315 46 4 3.3410e-04 cellular_component organellar large ribosomal subunit 1 1 1 1 GO:0000313 75 4 2.0227e-03 cellular_component organellar ribosome 1 1 1 1 GO:0016874 319 7 7.4192e-03 molecular_function ligase activity 1 1 1 1 1 1 1 GO:0016875 60 2 6.7135e-02 molecular_function ligase activity, forming carbon-oxygen bonds 1 1 GO:0016876 60 2 6.7135e-02 molecular_function ligase activity, forming aminoacyl-tRNA and related compounds 1 1 GO:0000070 32 0 1.0000e+00 biological_process mitotic sister chromatid segregation GO:0000074 200 4 5.3064e-02 biological_process regulation of progression through cell cycle 1 1 1 1 GO:0001871 80 1 4.3110e-01 molecular_function pattern binding 1 GO:0007409 124 0 1.0000e+00 biological_process axonogenesis GO:0006044 72 0 1.0000e+00 biological_process N-acetylglucosamine metabolism GO:0019932 90 0 1.0000e+00 biological_process second-messenger-mediated signaling GO:0016265 299 0 1.0000e+00 biological_process death GO:0016706 33 0 1.0000e+00 molecular_function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors GO:0045892 101 0 1.0000e+00 biological_process negative regulation of transcription, DNA-dependent GO:0045893 49 0 1.0000e+00 biological_process positive regulation of transcription, DNA-dependent GO:0003724 59 0 1.0000e+00 molecular_function RNA helicase activity GO:0003723 376 8 5.1189e-03 molecular_function RNA binding 1 1 1 1 1 1 1 1 GO:0003729 318 7 7.2988e-03 molecular_function mRNA binding 1 1 1 1 1 1 1 GO:0000267 96 0 1.0000e+00 cellular_component cell fraction GO:0007281 118 1 5.6531e-01 biological_process germ cell development 1 GO:0007283 115 0 1.0000e+00 biological_process spermatogenesis GO:0007286 40 0 1.0000e+00 biological_process spermatid development GO:0006887 128 2 2.2728e-01 biological_process exocytosis 1 1 GO:0008643 81 1 4.3511e-01 biological_process carbohydrate transport 1 GO:0016070 372 3 4.8748e-01 biological_process RNA metabolism 1 1 1 GO:0016071 212 1 7.7732e-01 biological_process mRNA metabolism 1 GO:0016072 43 0 1.0000e+00 biological_process rRNA metabolism GO:0016079 48 1 2.8683e-01 biological_process synaptic vesicle exocytosis 1 GO:0008509 95 0 1.0000e+00 molecular_function anion transporter activity GO:0045165 197 0 1.0000e+00 biological_process cell fate commitment GO:0050791 1364 11 3.6278e-01 biological_process regulation of physiological process 1 1 1 1 1 1 1 1 1 1 1 GO:0030534 47 0 1.0000e+00 biological_process adult behavior GO:0030532 62 0 1.0000e+00 cellular_component small nuclear ribonucleoprotein complex GO:0043065 65 0 1.0000e+00 biological_process positive regulation of apoptosis GO:0006869 59 2 6.5205e-02 biological_process lipid transport 1 1 GO:0004702 179 1 7.1823e-01 molecular_function receptor signaling protein serine/threonine kinase activity 1 GO:0007548 52 1 3.0667e-01 biological_process sex differentiation 1 GO:0015267 186 0 1.0000e+00 molecular_function channel or pore class transporter activity GO:0015268 186 0 1.0000e+00 molecular_function alpha-type channel activity GO:0016791 183 1 7.2615e-01 molecular_function phosphoric monoester hydrolase activity 2 GO:0016790 34 0 1.0000e+00 molecular_function thiolester hydrolase activity GO:0016799 42 1 2.5600e-01 molecular_function hydrolase activity, hydrolyzing N-glycosyl compounds 1 GO:0050875 6312 66 6.8950e-06 biological_process cellular physiological process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0006412 502 12 2.1548e-04 biological_process protein biosynthesis 1 1 1 1 1 1 1 1 1 1 1 1 GO:0030182 153 0 1.0000e+00 biological_process neuron differentiation GO:0017111 530 3 7.2462e-01 molecular_function nucleoside-triphosphatase activity 1 1 1 GO:0042221 269 2 5.6623e-01 biological_process response to chemical stimulus 1 1 GO:0046698 257 1 8.3860e-01 biological_process metamorphosis (sensu Insecta) 1 GO:0007431 110 0 1.0000e+00 biological_process salivary gland development GO:0031589 31 0 1.0000e+00 biological_process cell-substrate adhesion GO:0007424 112 2 1.8635e-01 biological_process tracheal system development (sensu Insecta) 1 1 GO:0016798 108 1 5.3338e-01 molecular_function hydrolase activity, acting on glycosyl bonds 1 GO:0009063 49 3 5.1483e-03 biological_process amino acid catabolism 1 1 1 GO:0009060 48 3 4.8640e-03 biological_process aerobic respiration 1 1 1 GO:0007423 79 0 1.0000e+00 biological_process sensory organ development GO:0009611 34 0 1.0000e+00 biological_process response to wounding GO:0007422 143 0 1.0000e+00 biological_process peripheral nervous system development GO:0000819 32 0 1.0000e+00 biological_process sister chromatid segregation GO:0007507 63 0 1.0000e+00 biological_process heart development GO:0050794 1404 10 5.3171e-01 biological_process regulation of cellular process 1 1 1 1 1 1 1 1 1 1 GO:0005941 74 0 1.0000e+00 cellular_component unlocalized protein complex GO:0006766 36 0 1.0000e+00 biological_process vitamin metabolism GO:0044257 82 1 4.3909e-01 biological_process cellular protein catabolism 1 GO:0044255 337 8 2.6603e-03 biological_process cellular lipid metabolism 1 1 1 1 1 1 1 1 GO:0000381 50 0 1.0000e+00 biological_process regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000380 51 0 1.0000e+00 biological_process alternative nuclear mRNA splicing, via spliceosome GO:0004540 44 0 1.0000e+00 molecular_function ribonuclease activity GO:0008017 76 0 1.0000e+00 molecular_function microtubule binding GO:0008010 40 0 1.0000e+00 molecular_function structural constituent of larval cuticle (sensu Insecta) GO:0004725 31 0 1.0000e+00 molecular_function protein tyrosine phosphatase activity GO:0004722 39 0 1.0000e+00 molecular_function protein serine/threonine phosphatase activity GO:0004721 89 0 1.0000e+00 molecular_function phosphoprotein phosphatase activity GO:0015203 39 0 1.0000e+00 molecular_function polyamine transporter activity GO:0019201 32 1 2.0166e-01 molecular_function nucleotide kinase activity 1 GO:0019204 36 1 2.2385e-01 molecular_function nucleotide phosphatase activity 2 GO:0019205 34 1 2.1283e-01 molecular_function nucleobase, nucleoside, nucleotide kinase activity 1 GO:0019208 32 0 1.0000e+00 molecular_function phosphatase regulator activity GO:0019752 394 13 4.1268e-06 biological_process carboxylic acid metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0007155 316 1 8.9434e-01 biological_process cell adhesion 1 GO:0007154 1567 7 9.3393e-01 biological_process cell communication 1 1 1 1 1 1 1 GO:0006575 49 0 1.0000e+00 biological_process amino acid derivative metabolism GO:0006576 30 0 1.0000e+00 biological_process biogenic amine metabolism GO:0015992 78 1 4.2299e-01 biological_process proton transport 1 GO:0009260 91 1 4.7369e-01 biological_process ribonucleotide biosynthesis 1 GO:0009266 55 0 1.0000e+00 biological_process response to temperature stimulus GO:0050793 82 0 1.0000e+00 biological_process regulation of development GO:0030703 55 0 1.0000e+00 biological_process eggshell formation GO:0030707 126 0 1.0000e+00 biological_process ovarian follicle cell development (sensu Insecta) GO:0030705 104 1 5.1997e-01 biological_process cytoskeleton-dependent intracellular transport 1 GO:0008652 73 3 1.5093e-02 biological_process amino acid biosynthesis 1 1 1 GO:0001654 185 0 1.0000e+00 biological_process eye development GO:0008354 33 0 1.0000e+00 biological_process germ cell migration GO:0035071 72 0 1.0000e+00 biological_process salivary gland cell autophagic cell death GO:0019001 166 2 3.2577e-01 molecular_function guanyl nucleotide binding 1 1 GO:0046983 50 0 1.0000e+00 molecular_function protein dimerization activity GO:0040011 271 3 2.9739e-01 biological_process locomotion 1 1 1 GO:0048729 46 0 1.0000e+00 biological_process tissue morphogenesis GO:0005829 185 1 7.3002e-01 cellular_component cytosol 1 GO:0006916 38 0 1.0000e+00 biological_process anti-apoptosis GO:0006917 63 0 1.0000e+00 biological_process induction of apoptosis GO:0006457 131 2 2.3504e-01 biological_process protein folding 1 1 GO:0004527 41 0 1.0000e+00 molecular_function exonuclease activity GO:0005214 82 0 1.0000e+00 molecular_function structural constituent of cuticle (sensu Insecta) GO:0005215 982 8 3.8627e-01 molecular_function transporter activity 1 1 1 1 1 1 1 1 GO:0005216 168 0 1.0000e+00 molecular_function ion channel activity GO:0004295 235 0 1.0000e+00 molecular_function trypsin activity GO:0008298 50 0 1.0000e+00 biological_process intracellular mRNA localization GO:0008293 33 0 1.0000e+00 biological_process torso signaling pathway GO:0019226 377 1 9.3195e-01 biological_process transmission of nerve impulse 1 GO:0019221 33 0 1.0000e+00 biological_process cytokine and chemokine mediated signaling pathway GO:0019730 64 0 1.0000e+00 biological_process antimicrobial humoral response GO:0019731 38 0 1.0000e+00 biological_process antibacterial humoral response GO:0007173 39 0 1.0000e+00 biological_process epidermal growth factor receptor signaling pathway GO:0007179 30 1 1.9033e-01 biological_process transforming growth factor beta receptor signaling pathway 1 GO:0007178 52 1 3.0667e-01 biological_process transmembrane receptor protein serine/threonine kinase signaling pathway 1 GO:0016757 162 1 6.8198e-01 molecular_function transferase activity, transferring glycosyl groups 1 GO:0016758 132 1 6.0641e-01 molecular_function transferase activity, transferring hexosyl groups 1 GO:0016283 39 0 1.0000e+00 cellular_component eukaryotic 48S initiation complex GO:0016282 60 0 1.0000e+00 cellular_component eukaryotic 43S preinitiation complex GO:0044270 52 3 6.0609e-03 biological_process nitrogen compound catabolism 1 1 1 GO:0012501 250 0 1.0000e+00 biological_process programmed cell death GO:0012502 71 0 1.0000e+00 biological_process induction of programmed cell death GO:0012505 150 0 1.0000e+00 cellular_component endomembrane system GO:0012506 32 0 1.0000e+00 cellular_component vesicle membrane GO:0031012 46 0 1.0000e+00 cellular_component extracellular matrix GO:0042773 63 5 9.0124e-05 biological_process ATP synthesis coupled electron transport 1 1 1 1 1 GO:0043632 77 0 1.0000e+00 biological_process modification-dependent macromolecule catabolism GO:0017157 46 0 1.0000e+00 biological_process regulation of exocytosis GO:0008194 93 1 4.8108e-01 molecular_function UDP-glycosyltransferase activity 1 GO:0004888 451 0 1.0000e+00 molecular_function transmembrane receptor activity GO:0006820 100 0 1.0000e+00 biological_process anion transport GO:0008372 844 4 8.5127e-01 cellular_component cellular component unknown 1 1 1 1 GO:0005840 190 4 4.5520e-02 cellular_component ribosome 1 1 1 1 GO:0005843 39 0 1.0000e+00 cellular_component cytosolic small ribosomal subunit (sensu Eukaryota) GO:0005842 52 0 1.0000e+00 cellular_component cytosolic large ribosomal subunit (sensu Eukaryota) GO:0030001 151 0 1.0000e+00 biological_process metal ion transport GO:0005976 163 1 6.8424e-01 biological_process polysaccharide metabolism 1 GO:0003700 398 3 5.3286e-01 molecular_function transcription factor activity 1 1 1 GO:0003682 84 1 4.4696e-01 molecular_function chromatin binding 1 GO:0003702 273 0 1.0000e+00 molecular_function RNA polymerase II transcription factor activity GO:0003704 82 0 1.0000e+00 molecular_function specific RNA polymerase II transcription factor activity GO:0048193 37 0 1.0000e+00 biological_process Golgi vesicle transport GO:0005279 39 0 1.0000e+00 molecular_function amino acid-polyamine transporter activity GO:0016779 93 0 1.0000e+00 molecular_function nucleotidyltransferase activity GO:0016773 365 1 9.2579e-01 molecular_function phosphotransferase activity, alcohol group as acceptor 1 GO:0016772 514 2 8.8045e-01 molecular_function transferase activity, transferring phosphorus-containing groups 1 1 GO:0042175 42 0 1.0000e+00 cellular_component nuclear envelope-endoplasmic reticulum network GO:0043565 35 0 1.0000e+00 molecular_function sequence-specific DNA binding GO:0016829 160 7 1.4540e-04 molecular_function lyase activity 1 1 1 1 1 1 1 GO:0019866 175 7 2.5007e-04 cellular_component organelle inner membrane 1 1 1 1 1 1 1 GO:0006468 293 1 8.7534e-01 biological_process protein amino acid phosphorylation 1 GO:0006461 120 0 1.0000e+00 biological_process protein complex assembly GO:0006464 849 7 3.8839e-01 biological_process protein modification 1 1 1 1 1 1 1 GO:0035070 72 0 1.0000e+00 biological_process salivary gland histolysis GO:0007472 108 1 5.3338e-01 biological_process wing disc morphogenesis 1 GO:0007476 106 1 5.2672e-01 biological_process wing morphogenesis 1 GO:0008170 36 0 1.0000e+00 molecular_function N-methyltransferase activity GO:0000151 126 3 5.9695e-02 cellular_component ubiquitin ligase complex 1 1 1 GO:0016125 34 0 1.0000e+00 biological_process sterol metabolism GO:0030247 67 0 1.0000e+00 molecular_function polysaccharide binding GO:0030246 114 0 1.0000e+00 molecular_function carbohydrate binding GO:0030029 102 0 1.0000e+00 biological_process actin filament-based process GO:0006259 377 2 7.4648e-01 biological_process DNA metabolism 1 1 GO:0005783 117 0 1.0000e+00 cellular_component endoplasmic reticulum GO:0005789 41 0 1.0000e+00 cellular_component endoplasmic reticulum membrane GO:0009968 49 0 1.0000e+00 biological_process negative regulation of signal transduction GO:0048732 132 0 1.0000e+00 biological_process gland development GO:0043170 3151 30 4.0848e-02 biological_process macromolecule metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0005529 48 0 1.0000e+00 molecular_function sugar binding GO:0005524 686 7 2.0800e-01 molecular_function ATP binding 1 1 1 1 1 1 1 GO:0005525 165 2 3.2319e-01 molecular_function GTP binding 1 1 GO:0007456 177 0 1.0000e+00 biological_process eye development (sensu Endopterygota) GO:0015629 75 1 4.1063e-01 cellular_component actin cytoskeleton 1 GO:0046907 629 4 6.5015e-01 biological_process intracellular transport 1 1 1 1 GO:0044238 4617 45 5.4267e-03 biological_process primary metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0009206 68 1 3.8074e-01 biological_process purine ribonucleoside triphosphate biosynthesis 1 GO:0009205 69 1 3.8510e-01 biological_process purine ribonucleoside triphosphate metabolism 1 GO:0009201 68 1 3.8074e-01 biological_process ribonucleoside triphosphate biosynthesis 1 GO:0006445 73 2 9.3825e-02 biological_process regulation of translation 1 1 GO:0048534 74 0 1.0000e+00 biological_process hemopoietic or lymphoid organ development GO:0048637 43 0 1.0000e+00 biological_process skeletal muscle development GO:0007559 73 0 1.0000e+00 biological_process histolysis GO:0008150 8219 76 6.0799e-05 biological_process biological_process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0008152 5111 57 1.0607e-05 biological_process metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0031410 89 1 4.6619e-01 cellular_component cytoplasmic vesicle 1 GO:0007606 168 0 1.0000e+00 biological_process sensory perception of chemical stimulus GO:0045595 44 0 1.0000e+00 biological_process regulation of cell differentiation GO:0044237 4680 53 2.1078e-05 biological_process cellular metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0015101 30 0 1.0000e+00 molecular_function organic cation transporter activity GO:0015103 40 0 1.0000e+00 molecular_function inorganic anion transporter activity GO:0005887 201 1 7.5913e-01 cellular_component integral to plasma membrane 1 GO:0005886 550 3 7.4765e-01 cellular_component plasma membrane 1 1 1 GO:0007015 64 0 1.0000e+00 biological_process actin filament organization GO:0007017 203 1 7.6255e-01 biological_process microtubule-based process 1 GO:0007010 464 4 4.1221e-01 biological_process cytoskeleton organization and biogenesis 1 1 1 1 GO:0007018 103 1 5.1656e-01 biological_process microtubule-based movement 1 GO:0016458 45 0 1.0000e+00 biological_process gene silencing GO:0009887 344 1 9.1364e-01 biological_process organ morphogenesis 1 GO:0031175 146 0 1.0000e+00 biological_process neurite development GO:0009948 121 0 1.0000e+00 biological_process anterior/posterior axis specification GO:0035239 66 1 3.7193e-01 biological_process tube morphogenesis 1 GO:0009416 49 0 1.0000e+00 biological_process response to light stimulus GO:0042051 45 0 1.0000e+00 biological_process eye photoreceptor development (sensu Endopterygota) GO:0005509 222 2 4.6376e-01 molecular_function calcium ion binding 1 1 GO:0005506 43 2 3.7199e-02 molecular_function iron ion binding 1 1 GO:0050909 60 0 1.0000e+00 biological_process sensory perception of taste GO:0046942 55 1 3.2120e-01 biological_process carboxylic acid transport 1 GO:0016591 85 0 1.0000e+00 cellular_component DNA-directed RNA polymerase II, holoenzyme GO:0007467 90 0 1.0000e+00 biological_process photoreceptor cell differentiation (sensu Endopterygota) GO:0048754 32 1 2.0166e-01 biological_process branching morphogenesis of a tube 1 GO:0019829 69 1 3.8510e-01 molecular_function cation-transporting ATPase activity 1 GO:0009880 131 0 1.0000e+00 biological_process embryonic pattern specification GO:0009889 80 2 1.0926e-01 biological_process regulation of biosynthesis 1 1 GO:0009888 416 1 9.4869e-01 biological_process tissue development 1 GO:0035218 39 0 1.0000e+00 biological_process leg disc development GO:0046148 41 0 1.0000e+00 biological_process pigment biosynthesis GO:0008134 92 1 4.7740e-01 molecular_function transcription factor binding 1 GO:0008135 84 2 1.1837e-01 molecular_function translation factor activity, nucleic acid binding 1 1 GO:0048232 115 0 1.0000e+00 biological_process male gamete generation GO:0045202 41 0 1.0000e+00 cellular_component synapse GO:0009628 380 2 7.5044e-01 biological_process response to abiotic stimulus 1 1 GO:0042440 48 0 1.0000e+00 biological_process pigment metabolism GO:0019888 32 0 1.0000e+00 molecular_function protein phosphatase regulator activity GO:0016477 182 0 1.0000e+00 biological_process cell migration GO:0042303 35 0 1.0000e+00 biological_process molting cycle GO:0042302 100 0 1.0000e+00 molecular_function structural constituent of cuticle GO:0043414 42 0 1.0000e+00 biological_process biopolymer methylation GO:0003712 76 0 1.0000e+00 molecular_function transcription cofactor activity GO:0005743 170 7 2.1002e-04 cellular_component mitochondrial inner membrane 1 1 1 1 1 1 1 GO:0005740 206 10 2.1121e-06 cellular_component mitochondrial envelope 1 1 1 1 1 1 1 1 1 1 GO:0005746 70 5 1.4685e-04 cellular_component mitochondrial electron transport chain 1 1 1 1 1 GO:0005747 38 5 8.2611e-06 cellular_component respiratory chain complex I (sensu Eukaryota) 1 1 1 1 1 GO:0000910 89 0 1.0000e+00 biological_process cytokinesis GO:0048747 43 0 1.0000e+00 biological_process muscle fiber development GO:0051252 57 0 1.0000e+00 biological_process regulation of RNA metabolism GO:0015662 74 1 4.0645e-01 molecular_function ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1 GO:0015931 37 0 1.0000e+00 biological_process nucleobase, nucleoside, nucleotide and nucleic acid transport GO:0015934 97 4 5.0357e-03 cellular_component large ribosomal subunit 1 1 1 1 GO:0015935 69 2 8.5317e-02 cellular_component small ribosomal subunit 1 1 GO:0016311 110 0 1.0000e+00 biological_process dephosphorylation GO:0016310 470 7 4.8114e-02 biological_process phosphorylation 1 1 1 1 1 1 1 GO:0046164 51 0 1.0000e+00 biological_process alcohol catabolism GO:0030414 87 0 1.0000e+00 molecular_function protease inhibitor activity GO:0048489 85 1 4.5086e-01 biological_process synaptic vesicle transport 1 GO:0006403 94 1 4.8474e-01 biological_process RNA localization 1 GO:0005179 52 1 3.0667e-01 molecular_function hormone activity 1 GO:0016491 631 16 8.3687e-06 molecular_function oxidoreductase activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0009607 524 3 7.1740e-01 biological_process response to biotic stimulus 1 1 1 GO:0009605 108 0 1.0000e+00 biological_process response to external stimulus GO:0005230 53 0 1.0000e+00 molecular_function extracellular ligand-gated ion channel activity GO:0005231 48 0 1.0000e+00 molecular_function excitatory extracellular ligand-gated ion channel activity GO:0007051 30 0 1.0000e+00 biological_process spindle organization and biogenesis GO:0007059 127 1 5.9220e-01 biological_process chromosome segregation 1 GO:0016410 33 1 2.0727e-01 molecular_function N-acyltransferase activity 1 GO:0006099 48 3 4.8640e-03 biological_process tricarboxylic acid cycle 1 1 1 GO:0006092 105 3 3.8310e-02 biological_process main pathways of carbohydrate metabolism 1 1 1 GO:0006091 509 14 1.3392e-05 biological_process generation of precursor metabolites and energy 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0006096 39 0 1.0000e+00 biological_process glycolysis GO:0048699 185 0 1.0000e+00 biological_process neurogenesis GO:0005761 75 4 2.0227e-03 cellular_component mitochondrial ribosome 1 1 1 1 GO:0005762 46 4 3.3410e-04 cellular_component mitochondrial large ribosomal subunit 1 1 1 1 GO:0005763 30 2 1.9197e-02 cellular_component mitochondrial small ribosomal subunit 1 1 GO:0004497 110 0 1.0000e+00 molecular_function monooxygenase activity GO:0007610 199 2 4.0881e-01 biological_process behavior 1 1 GO:0005549 117 0 1.0000e+00 molecular_function odorant binding GO:0051242 163 0 1.0000e+00 biological_process positive regulation of cellular physiological process GO:0008270 613 5 4.3272e-01 molecular_function zinc ion binding 1 1 1 1 1 GO:0051244 1321 9 5.8984e-01 biological_process regulation of cellular physiological process 1 1 1 1 1 1 1 1 1 GO:0016331 85 0 1.0000e+00 biological_process morphogenesis of embryonic epithelium GO:0016337 133 0 1.0000e+00 biological_process cell-cell adhesion GO:0046365 51 0 1.0000e+00 biological_process monosaccharide catabolism GO:0035114 133 1 6.0920e-01 biological_process appendage morphogenesis (sensu Endopterygota) 1 GO:0006399 89 2 1.3001e-01 biological_process tRNA metabolism 1 1 GO:0048523 271 1 8.5402e-01 biological_process negative regulation of cellular process 1 GO:0043296 34 0 1.0000e+00 cellular_component apical junction complex GO:0006396 258 1 8.3976e-01 biological_process RNA processing 1 GO:0006397 201 1 7.5913e-01 biological_process mRNA processing 1 GO:0044275 68 1 3.8074e-01 biological_process cellular carbohydrate catabolism 1 GO:0007411 88 0 1.0000e+00 biological_process axon guidance GO:0045184 534 4 5.2016e-01 biological_process establishment of protein localization 1 1 1 1 GO:0045182 88 2 1.2766e-01 molecular_function translation regulator activity 1 1 GO:0007568 48 0 1.0000e+00 biological_process aging GO:0007560 246 1 8.2538e-01 biological_process imaginal disc morphogenesis 1 GO:0016301 412 2 7.8944e-01 molecular_function kinase activity 1 1 GO:0048749 136 0 1.0000e+00 biological_process compound eye development (sensu Endopterygota) GO:0019200 33 1 2.0727e-01 molecular_function carbohydrate kinase activity 1 GO:0019207 67 0 1.0000e+00 molecular_function kinase regulator activity GO:0001708 56 0 1.0000e+00 biological_process cell fate specification GO:0001709 112 0 1.0000e+00 biological_process cell fate determination GO:0045935 67 0 1.0000e+00 biological_process positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism GO:0016651 44 5 1.6633e-05 molecular_function oxidoreductase activity, acting on NADH or NADPH 1 1 1 1 1 GO:0043228 745 6 4.2673e-01 cellular_component non-membrane-bound organelle 1 1 1 1 1 1 GO:0040008 62 0 1.0000e+00 biological_process regulation of growth GO:0005700 48 0 1.0000e+00 cellular_component polytene chromosome GO:0048589 40 0 1.0000e+00 biological_process developmental growth GO:0045045 222 3 2.0559e-01 biological_process secretory pathway 1 1 1 GO:0045451 33 0 1.0000e+00 biological_process pole plasm oskar mRNA localization GO:0007399 530 0 1.0000e+00 biological_process nervous system development GO:0007398 249 0 1.0000e+00 biological_process ectoderm development GO:0007391 77 0 1.0000e+00 biological_process dorsal closure GO:0016358 37 0 1.0000e+00 biological_process dendrite development GO:0046961 63 1 3.5847e-01 molecular_function hydrogen-transporting ATPase activity, rotational mechanism 1 GO:0048565 63 0 1.0000e+00 biological_process gut development GO:0048567 40 0 1.0000e+00 biological_process ectodermal gut morphogenesis GO:0006118 336 10 1.3340e-04 biological_process electron transport 1 1 1 1 1 1 1 1 1 1 GO:0006119 142 6 5.2727e-04 biological_process oxidative phosphorylation 1 1 1 1 1 1 GO:0004842 139 3 7.5203e-02 molecular_function ubiquitin-protein ligase activity 1 1 1 GO:0004843 30 0 1.0000e+00 molecular_function ubiquitin-specific protease activity GO:0004840 33 0 1.0000e+00 molecular_function ubiquitin conjugating enzyme activity GO:0031497 51 0 1.0000e+00 biological_process chromatin assembly GO:0004263 208 0 1.0000e+00 molecular_function chymotrypsin activity GO:0007400 30 0 1.0000e+00 biological_process neuroblast fate determination GO:0003899 31 0 1.0000e+00 molecular_function DNA-directed RNA polymerase activity GO:0006281 112 1 5.4642e-01 biological_process DNA repair 1 GO:0007186 320 0 1.0000e+00 biological_process G-protein coupled receptor protein signaling pathway GO:0006631 103 4 6.2020e-03 biological_process fatty acid metabolism 1 1 1 1 GO:0046943 72 1 3.9800e-01 molecular_function carboxylic acid transporter activity 1 GO:0004984 63 0 1.0000e+00 molecular_function olfactory receptor activity GO:0006960 45 0 1.0000e+00 biological_process antimicrobial humoral response (sensu Protostomia) GO:0005554 784 4 8.0791e-01 molecular_function molecular function unknown 1 1 1 1 GO:0004182 32 0 1.0000e+00 molecular_function carboxypeptidase A activity GO:0004181 32 0 1.0000e+00 molecular_function metallocarboxypeptidase activity GO:0004180 43 0 1.0000e+00 molecular_function carboxypeptidase activity GO:0004674 215 1 7.8204e-01 molecular_function protein serine/threonine kinase activity 1 GO:0004672 303 1 8.8399e-01 molecular_function protein kinase activity 1 GO:0007218 32 0 1.0000e+00 biological_process neuropeptide signaling pathway GO:0007219 41 0 1.0000e+00 biological_process Notch signaling pathway GO:0046873 32 0 1.0000e+00 molecular_function metal ion transporter activity GO:0046872 947 9 2.2136e-01 molecular_function metal ion binding 1 1 1 1 1 1 1 1 1 GO:0035214 163 0 1.0000e+00 biological_process eye-antennal disc development GO:0051674 266 3 2.8782e-01 biological_process localization of cell 1 1 1 GO:0006355 802 3 9.2586e-01 biological_process regulation of transcription, DNA-dependent 1 1 1 GO:0006357 558 2 9.0725e-01 biological_process regulation of transcription from RNA polymerase II promoter 1 1 GO:0006350 962 3 9.6897e-01 biological_process transcription 1 1 1 GO:0006351 912 3 9.5900e-01 biological_process transcription, DNA-dependent 1 1 1 GO:0006352 87 0 1.0000e+00 biological_process transcription initiation GO:0009617 74 1 4.0645e-01 biological_process response to bacteria 1 GO:0042578 201 1 7.5913e-01 molecular_function phosphoric ester hydrolase activity 2 GO:0042579 35 0 1.0000e+00 cellular_component microbody GO:0006139 1796 10 8.2669e-01 biological_process nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 1 1 1 1 1 1 1 1 1 GO:0048113 43 0 1.0000e+00 biological_process pole plasm assembly (sensu Insecta) GO:0004866 86 0 1.0000e+00 molecular_function endopeptidase inhibitor activity GO:0004867 71 0 1.0000e+00 molecular_function serine-type endopeptidase inhibitor activity GO:0046530 102 0 1.0000e+00 biological_process photoreceptor cell differentiation GO:0048547 40 0 1.0000e+00 biological_process gut morphogenesis GO:0048546 40 0 1.0000e+00 biological_process digestive tract morphogenesis GO:0009112 78 3 1.7958e-02 biological_process nucleobase metabolism 1 1 1 GO:0009117 162 2 3.1546e-01 biological_process nucleotide metabolism 1 1 GO:0001745 136 0 1.0000e+00 biological_process compound eye morphogenesis (sensu Endopterygota) GO:0042386 30 0 1.0000e+00 biological_process hemocyte differentiation (sensu Arthropoda) GO:0050808 32 0 1.0000e+00 biological_process synapse organization and biogenesis GO:0043190 44 0 1.0000e+00 cellular_component ATP-binding cassette (ABC) transporter complex GO:0048488 36 0 1.0000e+00 biological_process synaptic vesicle endocytosis GO:0030135 74 1 4.0645e-01 cellular_component coated vesicle 1 GO:0030136 62 1 3.5393e-01 cellular_component clathrin-coated vesicle 1 GO:0001653 52 0 1.0000e+00 molecular_function peptide receptor activity GO:0031974 418 7 2.8275e-02 cellular_component membrane-enclosed lumen 1 1 1 1 1 1 1 GO:0031975 271 10 2.2574e-05 cellular_component envelope 1 1 1 1 1 1 1 1 1 1 GO:0019887 35 0 1.0000e+00 molecular_function protein kinase regulator activity GO:0007351 50 0 1.0000e+00 biological_process regional subdivision GO:0007350 104 0 1.0000e+00 biological_process blastoderm segmentation GO:0048511 38 0 1.0000e+00 biological_process rhythmic process GO:0048513 657 3 8.4606e-01 biological_process organ development 1 1 1 GO:0048515 40 0 1.0000e+00 biological_process spermatid differentiation GO:0006338 42 0 1.0000e+00 biological_process chromatin remodeling GO:0006333 100 0 1.0000e+00 biological_process chromatin assembly or disassembly GO:0043492 155 1 6.6575e-01 molecular_function ATPase activity, coupled to movement of substances 1 GO:0042592 80 1 4.3110e-01 biological_process homeostasis 1 GO:0042598 83 0 1.0000e+00 cellular_component vesicular fraction GO:0006486 83 1 4.4304e-01 biological_process protein amino acid glycosylation 1 GO:0008356 54 0 1.0000e+00 biological_process asymmetric cell division GO:0043167 947 9 2.2136e-01 molecular_function ion binding 1 1 1 1 1 1 1 1 1 GO:0008355 40 1 2.4543e-01 biological_process olfactory learning 1 GO:0005684 41 0 1.0000e+00 cellular_component major (U2-dependent) spliceosome GO:0005681 94 0 1.0000e+00 cellular_component spliceosome complex GO:0048812 124 0 1.0000e+00 biological_process neurite morphogenesis GO:0004222 73 0 1.0000e+00 molecular_function metalloendopeptidase activity GO:0001763 35 1 2.1836e-01 biological_process morphogenesis of a branching structure 1 GO:0008083 33 0 1.0000e+00 molecular_function growth factor activity GO:0008080 30 0 1.0000e+00 molecular_function N-acetyltransferase activity GO:0008553 49 1 2.9184e-01 molecular_function hydrogen-exporting ATPase activity, phosphorylative mechanism 1 GO:0007612 44 1 2.6642e-01 biological_process learning 1 GO:0009144 69 1 3.8510e-01 biological_process purine nucleoside triphosphate metabolism 1 GO:0009145 68 1 3.8074e-01 biological_process purine nucleoside triphosphate biosynthesis 1 GO:0006928 266 3 2.8782e-01 biological_process cell motility 1 1 1 GO:0048112 47 0 1.0000e+00 biological_process oocyte anterior/posterior axis determination (sensu Insecta) GO:0042625 97 1 4.9557e-01 molecular_function ATPase activity, coupled to transmembrane movement of ions 1 GO:0042626 155 1 6.6575e-01 molecular_function ATPase activity, coupled to transmembrane movement of substances 1 GO:0035295 80 1 4.3110e-01 biological_process tube development 1 GO:0042623 334 2 6.8380e-01 molecular_function ATPase activity, coupled 1 1 GO:0005096 47 2 4.3653e-02 molecular_function GTPase activator activity 1 1 GO:0000785 106 0 1.0000e+00 cellular_component chromatin GO:0042742 69 1 3.8510e-01 biological_process defense response to bacteria 1 GO:0007254 49 1 2.9184e-01 biological_process JNK cascade 1 GO:0045934 126 0 1.0000e+00 biological_process negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism GO:0006310 42 1 2.5600e-01 biological_process DNA recombination 1 GO:0006913 72 1 3.9800e-01 biological_process nucleocytoplasmic transport 1 GO:0006818 78 1 4.2299e-01 biological_process hydrogen transport 1 GO:0008238 114 1 5.5281e-01 molecular_function exopeptidase activity 1 GO:0005667 89 0 1.0000e+00 cellular_component transcription factor complex GO:0008235 79 1 4.2706e-01 molecular_function metalloexopeptidase activity 1 GO:0008234 97 0 1.0000e+00 molecular_function cysteine-type peptidase activity GO:0009152 89 1 4.6619e-01 biological_process purine ribonucleotide biosynthesis 1 GO:0009150 90 1 4.6995e-01 biological_process purine ribonucleotide metabolism 1 GO:0031090 321 9 4.5074e-04 cellular_component organelle membrane 1 1 1 1 1 1 1 1 1 GO:0015294 63 0 1.0000e+00 molecular_function solute:cation symporter activity GO:0015297 32 0 1.0000e+00 molecular_function antiporter activity GO:0015296 39 0 1.0000e+00 molecular_function anion:cation symporter activity GO:0015291 218 0 1.0000e+00 molecular_function porter activity GO:0015290 218 0 1.0000e+00 molecular_function electrochemical potential-driven transporter activity GO:0015293 73 0 1.0000e+00 molecular_function symporter activity GO:0008202 137 2 2.5060e-01 biological_process steroid metabolism 1 1 GO:0005576 389 2 7.6199e-01 cellular_component extracellular region 1 1 GO:0015031 530 4 5.1421e-01 biological_process protein transport 1 1 1 1 GO:0042981 110 0 1.0000e+00 biological_process regulation of apoptosis GO:0003779 131 3 6.5463e-02 molecular_function actin binding 1 1 1 GO:0003774 87 0 1.0000e+00 molecular_function motor activity GO:0003777 50 0 1.0000e+00 molecular_function microtubule motor activity GO:0042254 32 0 1.0000e+00 biological_process ribosome biogenesis and assembly GO:0005342 74 1 4.0645e-01 molecular_function organic acid transporter activity 1 GO:0007270 48 0 1.0000e+00 biological_process nerve-nerve synaptic transmission GO:0007274 30 0 1.0000e+00 biological_process neuromuscular synaptic transmission GO:0007275 1527 12 3.8702e-01 biological_process development 1 1 1 1 1 1 1 1 1 1 1 1 GO:0007276 463 2 8.4066e-01 biological_process gametogenesis 1 1 GO:0007316 39 0 1.0000e+00 biological_process pole plasm RNA localization GO:0007315 45 0 1.0000e+00 biological_process pole plasm assembly GO:0007314 58 0 1.0000e+00 biological_process oocyte anterior/posterior axis determination GO:0044267 2103 21 5.7798e-02 biological_process cellular protein metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0016023 89 1 4.6619e-01 cellular_component cytoplasmic membrane-bound vesicle 1 GO:0016021 969 3 9.7017e-01 cellular_component integral to membrane 1 1 1 GO:0016020 1915 15 3.6813e-01 cellular_component membrane 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0007442 36 0 1.0000e+00 biological_process hindgut morphogenesis GO:0007447 45 0 1.0000e+00 biological_process imaginal disc pattern formation GO:0043234 1602 20 7.4240e-03 cellular_component protein complex 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0043235 38 0 1.0000e+00 cellular_component receptor complex GO:0043232 745 6 4.2673e-01 cellular_component intracellular non-membrane-bound organelle 1 1 1 1 1 1 GO:0043233 418 7 2.8275e-02 cellular_component organelle lumen 1 1 1 1 1 1 1 GO:0007444 309 2 6.4193e-01 biological_process imaginal disc development 1 1 GO:0005643 41 0 1.0000e+00 cellular_component nuclear pore GO:0019320 51 0 1.0000e+00 biological_process hexose catabolism GO:0006732 240 8 3.0587e-04 biological_process coenzyme metabolism 1 1 1 1 1 1 1 1 GO:0009310 52 3 6.0609e-03 biological_process amine catabolism 1 1 1 GO:0006030 63 0 1.0000e+00 biological_process chitin metabolism GO:0008047 97 2 1.4914e-01 molecular_function enzyme activator activity 1 1 GO:0044262 278 4 1.3282e-01 biological_process cellular carbohydrate metabolism 1 1 1 1 GO:0016849 33 0 1.0000e+00 molecular_function phosphorus-oxygen lyase activity GO:0008594 50 0 1.0000e+00 biological_process photoreceptor cell morphogenesis (sensu Endopterygota) GO:0008595 50 0 1.0000e+00 biological_process determination of anterior/posterior axis, embryo GO:0016271 73 0 1.0000e+00 biological_process tissue death GO:0030154 532 1 9.7796e-01 biological_process cell differentiation 1 GO:0016627 30 1 1.9033e-01 molecular_function oxidoreductase activity, acting on the CH-CH group of donors 1 GO:0042277 65 0 1.0000e+00 molecular_function peptide binding GO:0006508 764 3 9.0968e-01 biological_process proteolysis 1 1 1 GO:0051188 105 2 1.6880e-01 biological_process cofactor biosynthesis 1 1 GO:0009058 911 19 1.7245e-05 biological_process biosynthesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0009059 531 12 3.5781e-04 biological_process macromolecule biosynthesis 1 1 1 1 1 1 1 1 1 1 1 1 GO:0051170 49 1 2.9184e-01 biological_process nuclear import 1 GO:0031967 271 10 2.2574e-05 cellular_component organelle envelope 1 1 1 1 1 1 1 1 1 1 GO:0050684 55 0 1.0000e+00 biological_process regulation of mRNA processing GO:0007292 322 1 8.9881e-01 biological_process female gamete generation 1 GO:0007293 48 0 1.0000e+00 biological_process egg chamber formation (sensu Insecta) GO:0007297 34 0 1.0000e+00 biological_process follicle cell migration (sensu Insecta) GO:0018193 35 0 1.0000e+00 biological_process peptidyl-amino acid modification GO:0016049 30 1 1.9033e-01 biological_process cell growth 1 GO:0016044 32 0 1.0000e+00 biological_process membrane organization and biogenesis GO:0016043 1417 8 7.9099e-01 biological_process cell organization and biogenesis 1 1 1 1 1 1 1 1 GO:0042067 35 0 1.0000e+00 biological_process establishment of ommatidial polarity (sensu Endopterygota) GO:0043037 189 5 1.0987e-02 biological_process translation 1 1 1 1 1 GO:0008340 48 0 1.0000e+00 biological_process determination of adult life span GO:0008610 85 2 1.2068e-01 biological_process lipid biosynthesis 1 1 GO:0005624 93 0 1.0000e+00 cellular_component membrane fraction GO:0005623 4695 41 5.5283e-02 cellular_component cell 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0005622 3346 36 3.1560e-03 cellular_component intracellular 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0045941 66 0 1.0000e+00 biological_process positive regulation of transcription GO:0048066 40 0 1.0000e+00 biological_process pigmentation during development GO:0009993 289 0 1.0000e+00 biological_process oogenesis (sensu Insecta) GO:0005198 757 8 1.6335e-01 molecular_function structural molecule activity 1 1 1 1 1 1 1 1 GO:0008066 40 0 1.0000e+00 molecular_function glutamate receptor activity GO:0008061 63 0 1.0000e+00 molecular_function chitin binding GO:0008063 30 0 1.0000e+00 biological_process Toll signaling pathway GO:0000004 728 1 9.9480e-01 biological_process biological process unknown 1 GO:0043119 165 0 1.0000e+00 biological_process positive regulation of physiological process GO:0004714 32 0 1.0000e+00 molecular_function transmembrane receptor protein tyrosine kinase activity GO:0004713 90 0 1.0000e+00 molecular_function protein-tyrosine kinase activity GO:0003924 133 1 6.0920e-01 molecular_function GTPase activity 1 GO:0043118 231 2 4.8446e-01 biological_process negative regulation of physiological process 1 1 GO:0016787 1828 10 8.4293e-01 molecular_function hydrolase activity 1 1 1 1 1 1 1 1 1 2 GO:0016788 463 1 9.6353e-01 molecular_function hydrolase activity, acting on ester bonds 2 GO:0016789 124 0 1.0000e+00 molecular_function carboxylic ester hydrolase activity GO:0015075 493 1 9.7069e-01 molecular_function ion transporter activity 1 GO:0015077 105 1 5.2336e-01 molecular_function monovalent inorganic cation transporter activity 1 GO:0015078 103 1 5.1656e-01 molecular_function hydrogen ion transporter activity 1 GO:0048024 55 0 1.0000e+00 biological_process regulation of nuclear mRNA splicing, via spliceosome GO:0007126 90 1 4.6995e-01 biological_process meiosis 1 GO:0007127 32 0 1.0000e+00 biological_process meiosis I GO:0016251 103 0 1.0000e+00 molecular_function general RNA polymerase II transcription factor activity GO:0007417 124 0 1.0000e+00 biological_process central nervous system development GO:0006520 263 9 1.0455e-04 biological_process amino acid metabolism 1 1 1 1 1 1 1 1 1 GO:0003735 189 4 4.4801e-02 molecular_function structural constituent of ribosome 1 1 1 1 GO:0043067 120 0 1.0000e+00 biological_process regulation of programmed cell death GO:0043066 42 0 1.0000e+00 biological_process negative regulation of apoptosis GO:0043069 42 0 1.0000e+00 biological_process negative regulation of programmed cell death GO:0043068 76 0 1.0000e+00 biological_process positive regulation of programmed cell death GO:0000279 296 2 6.1851e-01 biological_process M phase 1 1 GO:0000278 278 1 8.6117e-01 biological_process mitotic cell cycle 1 GO:0051119 47 0 1.0000e+00 molecular_function sugar transporter activity GO:0004386 112 0 1.0000e+00 molecular_function helicase activity GO:0005386 458 6 1.0414e-01 molecular_function carrier activity 1 1 1 1 1 1 GO:0016820 156 1 6.6812e-01 molecular_function hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1 GO:0006897 121 1 5.7446e-01 biological_process endocytosis 1 GO:0016065 53 0 1.0000e+00 biological_process humoral defense mechanism (sensu Protostomia) GO:0007517 111 1 5.4320e-01 biological_process muscle development 1 GO:0042048 55 1 3.2120e-01 biological_process olfactory behavior 1 GO:0006725 147 3 8.5546e-02 biological_process aromatic compound metabolism 1 1 1 GO:0005813 36 0 1.0000e+00 cellular_component centrosome GO:0005815 42 0 1.0000e+00 cellular_component microtubule organizing center GO:0005975 488 7 5.6651e-02 biological_process carbohydrate metabolism 1 1 1 1 1 1 1 GO:0030054 68 1 3.8074e-01 cellular_component cell junction 1 GO:0007617 56 1 3.2597e-01 biological_process mating behavior 1 GO:0007611 61 1 3.4935e-01 biological_process learning and/or memory 1 GO:0007243 134 1 6.1196e-01 biological_process protein kinase cascade 1 GO:0000398 152 0 1.0000e+00 biological_process nuclear mRNA splicing, via spliceosome GO:0004553 102 1 5.1312e-01 molecular_function hydrolase activity, hydrolyzing O-glycosyl compounds 1 GO:0016881 158 3 1.0070e-01 molecular_function acid-amino acid ligase activity 1 1 1 GO:0016887 375 2 7.4382e-01 molecular_function ATPase activity 1 1 GO:0014016 30 0 1.0000e+00 biological_process neuroblast differentiation GO:0014017 30 0 1.0000e+00 biological_process neuroblast fate commitment GO:0004812 60 2 6.7135e-02 molecular_function aminoacyl-tRNA ligase activity 1 1 GO:0045333 48 3 4.8640e-03 biological_process cellular respiration 1 1 1 GO:0009719 137 1 6.2014e-01 biological_process response to endogenous stimulus 1 GO:0051321 95 1 4.8838e-01 biological_process meiotic cell cycle 1 GO:0007552 259 1 8.4090e-01 biological_process metamorphosis 1 GO:0015276 70 0 1.0000e+00 molecular_function ligand-gated ion channel activity GO:0019941 77 0 1.0000e+00 biological_process modification-dependent protein catabolism GO:0007143 39 0 1.0000e+00 biological_process female meiosis GO:0050789 1531 11 5.1704e-01 biological_process regulation of biological process 1 1 1 1 1 1 1 1 1 1 1 GO:0030198 32 0 1.0000e+00 biological_process extracellular matrix organization and biogenesis GO:0030286 40 0 1.0000e+00 cellular_component dynein complex GO:0016879 182 4 3.9950e-02 molecular_function ligase activity, forming carbon-nitrogen bonds 1 1 1 1 GO:0008639 34 0 1.0000e+00 molecular_function small protein conjugating enzyme activity GO:0040007 91 2 1.3474e-01 biological_process growth 1 1 GO:0044248 309 7 6.2797e-03 biological_process cellular catabolism 1 1 1 1 1 1 1 GO:0044249 842 17 7.6490e-05 biological_process cellular biosynthesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0048646 30 0 1.0000e+00 biological_process anatomical structure formation GO:0007439 40 0 1.0000e+00 biological_process ectodermal gut development GO:0005830 91 0 1.0000e+00 cellular_component cytosolic ribosome (sensu Eukaryota) GO:0007088 37 0 1.0000e+00 biological_process regulation of mitosis GO:0015849 55 1 3.2120e-01 biological_process organic acid transport 1 GO:0005488 4219 42 5.3617e-03 molecular_function binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0042923 49 0 1.0000e+00 molecular_function neuropeptide binding GO:0004536 38 0 1.0000e+00 molecular_function deoxyribonuclease activity GO:0006752 72 1 3.9800e-01 biological_process group transfer coenzyme metabolism 1 GO:0006753 64 1 3.6299e-01 biological_process nucleoside phosphate metabolism 1 GO:0006754 64 1 3.6299e-01 biological_process ATP biosynthesis 1 GO:0008021 56 1 3.2597e-01 cellular_component synaptic vesicle 1 GO:0008026 83 0 1.0000e+00 molecular_function ATP-dependent helicase activity GO:0008283 288 2 6.0353e-01 biological_process cell proliferation 1 1 GO:0008289 68 4 1.4187e-03 molecular_function lipid binding 1 1 1 1 GO:0051301 145 0 1.0000e+00 biological_process cell division GO:0019219 906 3 9.5762e-01 biological_process regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 1 1 GO:0019748 70 0 1.0000e+00 biological_process secondary metabolism GO:0035272 110 0 1.0000e+00 biological_process exocrine system development GO:0007160 31 0 1.0000e+00 biological_process cell-matrix adhesion GO:0007163 75 1 4.1063e-01 biological_process establishment and/or maintenance of cell polarity 1 GO:0007164 46 0 1.0000e+00 biological_process establishment of tissue polarity GO:0007165 1337 6 9.1756e-01 biological_process signal transduction 1 1 1 1 1 1 GO:0007166 684 2 9.5633e-01 biological_process cell surface receptor linked signal transduction 1 1 GO:0007167 176 1 7.1215e-01 biological_process enzyme linked receptor protein signaling pathway 1 GO:0007169 127 0 1.0000e+00 biological_process transmembrane receptor protein tyrosine kinase signaling pathway GO:0016740 988 11 8.6737e-02 molecular_function transferase activity 1 1 1 1 1 1 1 1 1 1 1 GO:0016741 87 1 4.5858e-01 molecular_function transferase activity, transferring one-carbon groups 1 GO:0016746 130 5 2.3332e-03 molecular_function transferase activity, transferring acyl groups 1 1 1 1 1 GO:0016747 123 5 1.8382e-03 molecular_function transferase activity, transferring groups other than amino-acyl groups 1 1 1 1 1 GO:0016567 113 3 4.5902e-02 biological_process protein ubiquitination 1 1 1 GO:0016564 60 0 1.0000e+00 molecular_function transcriptional repressor activity GO:0016563 56 0 1.0000e+00 molecular_function transcriptional activator activity GO:0016298 88 0 1.0000e+00 molecular_function lipase activity GO:0016568 61 0 1.0000e+00 biological_process chromatin modification GO:0015985 64 1 3.6299e-01 biological_process energy coupled proton transport, down electrochemical gradient 1 GO:0015986 64 1 3.6299e-01 biological_process ATP synthesis coupled proton transport 1 GO:0015980 119 3 5.2048e-02 biological_process energy derivation by oxidation of organic compounds 1 1 1 GO:0046394 31 0 1.0000e+00 biological_process carboxylic acid biosynthesis GO:0051243 222 1 7.9267e-01 biological_process negative regulation of cellular physiological process 1 GO:0051246 135 2 2.4540e-01 biological_process regulation of protein metabolism 1 1 GO:0009259 92 1 4.7740e-01 biological_process ribonucleotide metabolism 1 GO:0045271 38 5 8.2611e-06 cellular_component respiratory chain complex I 1 1 1 1 1 GO:0040029 75 0 1.0000e+00 biological_process regulation of gene expression, epigenetic GO:0015405 122 1 5.7747e-01 molecular_function P-P-bond-hydrolysis-driven transporter activity 1 GO:0007455 149 0 1.0000e+00 biological_process eye-antennal disc morphogenesis GO:0009994 91 0 1.0000e+00 biological_process oocyte differentiation GO:0005856 293 2 6.1294e-01 cellular_component cytoskeleton 1 1 GO:0005938 49 0 1.0000e+00 cellular_component cell cortex GO:0007519 50 0 1.0000e+00 biological_process striated muscle development GO:0030528 826 4 8.3920e-01 molecular_function transcription regulator activity 1 1 1 1 GO:0030529 322 5 7.7191e-02 cellular_component ribonucleoprotein complex 1 1 1 1 1 GO:0004518 91 0 1.0000e+00 molecular_function nuclease activity GO:0004519 50 0 1.0000e+00 molecular_function endonuclease activity GO:0006006 60 0 1.0000e+00 biological_process glucose metabolism GO:0006007 51 0 1.0000e+00 biological_process glucose catabolism GO:0005200 305 3 3.6270e-01 molecular_function structural constituent of cytoskeleton 1 1 1 GO:0042706 35 0 1.0000e+00 biological_process eye photoreceptor cell fate commitment GO:0043169 902 9 1.8328e-01 molecular_function cation binding 1 1 1 1 1 1 1 1 1 GO:0048666 146 0 1.0000e+00 biological_process neuron development GO:0048667 124 0 1.0000e+00 biological_process neuron morphogenesis during differentiation GO:0043062 43 0 1.0000e+00 biological_process extracellular structure organization and biogenesis GO:0000502 54 0 1.0000e+00 cellular_component proteasome complex (sensu Eukaryota) GO:0019725 70 1 3.8943e-01 biological_process cell homeostasis 1 GO:0019722 66 0 1.0000e+00 biological_process calcium-mediated signaling GO:0006898 39 0 1.0000e+00 biological_process receptor mediated endocytosis GO:0016765 61 1 3.4935e-01 molecular_function transferase activity, transferring alkyl or aryl (other than methyl) groups 1 GO:0044264 78 0 1.0000e+00 biological_process cellular polysaccharide metabolism GO:0044265 174 2 3.4625e-01 biological_process cellular macromolecule catabolism 1 1 GO:0044260 2177 21 7.7751e-02 biological_process cellular macromolecule metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0006413 59 1 3.4010e-01 biological_process translational initiation 1 GO:0017145 38 0 1.0000e+00 biological_process stem cell division GO:0002009 139 0 1.0000e+00 biological_process morphogenesis of an epithelium GO:0009581 45 0 1.0000e+00 biological_process detection of external stimulus GO:0009582 44 0 1.0000e+00 biological_process detection of abiotic stimulus GO:0009583 35 0 1.0000e+00 biological_process detection of light stimulus GO:0008188 49 0 1.0000e+00 molecular_function neuropeptide receptor activity GO:0008186 40 0 1.0000e+00 molecular_function RNA-dependent ATPase activity GO:0000165 109 1 5.3668e-01 biological_process MAPKKK cascade 1 GO:0000166 895 9 1.7765e-01 molecular_function nucleotide binding 1 1 1 1 1 1 1 1 1 GO:0019538 2208 22 5.3413e-02 biological_process protein metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0004091 32 0 1.0000e+00 molecular_function carboxylesterase activity GO:0000578 59 0 1.0000e+00 biological_process embryonic axis specification GO:0015399 122 1 5.7747e-01 molecular_function primary active transporter activity 1 GO:0015171 47 1 2.8178e-01 molecular_function amino acid transporter activity 1 GO:0005871 30 0 1.0000e+00 cellular_component kinesin complex GO:0005874 43 1 2.6122e-01 cellular_component microtubule 1 GO:0005875 117 0 1.0000e+00 cellular_component microtubule associated complex GO:0005912 51 1 3.0176e-01 cellular_component adherens junction 1 GO:0005911 46 0 1.0000e+00 cellular_component intercellular junction GO:0030030 50 0 1.0000e+00 biological_process cell projection organization and biogenesis GO:0030031 32 0 1.0000e+00 biological_process cell projection biogenesis GO:0030036 102 0 1.0000e+00 biological_process actin cytoskeleton organization and biogenesis GO:0007608 74 0 1.0000e+00 biological_process sensory perception of smell GO:0006606 48 1 2.8683e-01 biological_process protein import into nucleus 1 GO:0000375 152 0 1.0000e+00 biological_process RNA splicing, via transesterification reactions GO:0000377 152 0 1.0000e+00 biological_process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile GO:0006605 238 2 5.0022e-01 biological_process protein targeting 1 1 GO:0006793 615 7 1.4231e-01 biological_process phosphorus metabolism 1 1 1 1 1 1 1 GO:0005267 53 0 1.0000e+00 molecular_function potassium channel activity GO:0005261 117 0 1.0000e+00 molecular_function cation channel activity GO:0000087 233 1 8.0835e-01 biological_process M phase of mitotic cell cycle 1 GO:0006470 86 0 1.0000e+00 biological_process protein amino acid dephosphorylation GO:0016830 45 2 4.0376e-02 molecular_function carbon-carbon lyase activity 1 1 GO:0045055 110 1 5.3995e-01 biological_process regulated secretory pathway 1 GO:0008168 86 0 1.0000e+00 molecular_function methyltransferase activity GO:0006813 60 0 1.0000e+00 biological_process potassium ion transport GO:0006812 390 2 7.6324e-01 biological_process cation transport 1 1 GO:0006811 470 2 8.4675e-01 biological_process ion transport 1 1 GO:0006817 43 0 1.0000e+00 biological_process phosphate transport GO:0006814 46 0 1.0000e+00 biological_process sodium ion transport GO:0003824 3835 45 6.9759e-05 molecular_function catalytic activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0006959 79 0 1.0000e+00 biological_process humoral immune response GO:0051082 62 1 3.5393e-01 molecular_function unfolded protein binding 1 GO:0015370 62 0 1.0000e+00 molecular_function solute:sodium symporter activity GO:0007028 56 0 1.0000e+00 biological_process cytoplasm organization and biogenesis GO:0046034 65 1 3.6747e-01 biological_process ATP metabolism 1 GO:0030234 365 4 2.5530e-01 molecular_function enzyme regulator activity 1 1 1 1 GO:0019222 1043 5 8.6548e-01 biological_process regulation of metabolism 1 1 1 1 1 GO:0005057 242 1 8.2030e-01 molecular_function receptor signaling protein activity 1 GO:0031982 92 1 4.7740e-01 cellular_component vesicle 1 GO:0031981 259 0 1.0000e+00 cellular_component nuclear lumen GO:0031988 92 1 4.7740e-01 cellular_component membrane-bound vesicle 1 GO:0006260 122 2 2.1183e-01 biological_process DNA replication 1 1 GO:0006261 62 0 1.0000e+00 biological_process DNA-dependent DNA replication GO:0005794 91 0 1.0000e+00 cellular_component Golgi apparatus GO:0000314 30 2 1.9197e-02 cellular_component organellar small ribosomal subunit 1 1 GO:0048748 144 0 1.0000e+00 biological_process eye morphogenesis (sensu Endopterygota) GO:0009975 32 0 1.0000e+00 molecular_function cyclase activity GO:0005275 54 1 3.1639e-01 molecular_function amine transporter activity 1 GO:0048477 301 0 1.0000e+00 biological_process oogenesis GO:0006040 73 0 1.0000e+00 biological_process amino sugar metabolism GO:0001700 131 1 6.0361e-01 biological_process embryonic development (sensu Insecta) 1 GO:0005249 33 0 1.0000e+00 molecular_function voltage-gated potassium channel activity GO:0005244 51 0 1.0000e+00 molecular_function voltage-gated ion channel activity GO:0009791 362 3 4.6949e-01 biological_process post-embryonic development 1 1 1 GO:0009790 360 2 7.2307e-01 biological_process embryonic development 1 1 GO:0009792 199 1 7.5567e-01 biological_process embryonic development (sensu Metazoa) 1 GO:0009798 163 0 1.0000e+00 biological_process axis specification GO:0048741 43 0 1.0000e+00 biological_process skeletal muscle fiber development GO:0008415 117 5 1.4794e-03 molecular_function acyltransferase activity 1 1 1 1 1 GO:0015631 92 0 1.0000e+00 molecular_function tubulin binding GO:0015630 192 1 7.4316e-01 cellular_component microtubule cytoskeleton 1 GO:0046483 142 3 7.9013e-02 biological_process heterocycle metabolism 1 1 1 GO:0009892 155 0 1.0000e+00 biological_process negative regulation of metabolism GO:0009893 69 0 1.0000e+00 biological_process positive regulation of metabolism GO:0000122 53 0 1.0000e+00 biological_process negative regulation of transcription from RNA polymerase II promoter GO:0008324 405 1 9.4443e-01 molecular_function cation transporter activity 1 GO:0009636 130 1 6.0079e-01 biological_process response to toxin 1 GO:0007001 159 0 1.0000e+00 biological_process chromosome organization and biogenesis (sensu Eukaryota) GO:0009314 55 0 1.0000e+00 biological_process response to radiation GO:0046356 48 3 4.8640e-03 biological_process acetyl-CoA catabolism 1 1 1 GO:0006206 32 2 2.1646e-02 biological_process pyrimidine base metabolism 1 1 GO:0009953 76 0 1.0000e+00 biological_process dorsal/ventral pattern formation GO:0009952 133 0 1.0000e+00 biological_process anterior/posterior pattern formation GO:0009950 58 0 1.0000e+00 biological_process dorsal/ventral axis specification GO:0050896 1192 6 8.5314e-01 biological_process response to stimulus 1 1 1 1 1 1 GO:0031098 49 1 2.9184e-01 biological_process stress-activated protein kinase signaling pathway 1 GO:0009408 47 0 1.0000e+00 biological_process response to heat GO:0005516 72 1 3.9800e-01 molecular_function calmodulin binding 1 GO:0005515 1266 14 5.9448e-02 molecular_function protein binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0004177 42 1 2.5600e-01 molecular_function aminopeptidase activity 1 GO:0004175 480 0 1.0000e+00 molecular_function endopeptidase activity GO:0006996 743 5 6.0350e-01 biological_process organelle organization and biogenesis 1 1 1 1 1 GO:0035107 136 1 6.1743e-01 biological_process appendage morphogenesis 1 GO:0035220 120 1 5.7144e-01 biological_process wing disc development 1 GO:0051603 82 1 4.3909e-01 biological_process proteolysis during cellular protein catabolism 1 GO:0051606 49 0 1.0000e+00 biological_process detection of stimulus GO:0007619 34 0 1.0000e+00 biological_process courtship behavior GO:0043283 1705 15 2.1414e-01 biological_process biopolymer metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0043285 128 2 2.2728e-01 biological_process biopolymer catabolism 1 1 GO:0042462 46 0 1.0000e+00 biological_process eye photoreceptor cell development GO:0042461 53 0 1.0000e+00 biological_process photoreceptor cell development GO:0006858 124 0 1.0000e+00 biological_process extracellular transport GO:0046914 687 7 2.0900e-01 molecular_function transition metal ion binding 1 1 1 1 1 1 1 GO:0007459 43 0 1.0000e+00 biological_process photoreceptor fate commitment (sensu Endopterygota) GO:0009613 101 0 1.0000e+00 biological_process response to pest, pathogen or parasite GO:0007067 232 1 8.0698e-01 biological_process mitosis 1 GO:0006163 92 1 4.7740e-01 biological_process purine nucleotide metabolism 1 GO:0016684 32 0 1.0000e+00 molecular_function oxidoreductase activity, acting on peroxide as acceptor GO:0006164 91 1 4.7369e-01 biological_process purine nucleotide biosynthesis 1 GO:0016462 538 3 7.3402e-01 molecular_function pyrophosphatase activity 1 1 1 GO:0016469 68 1 3.8074e-01 cellular_component proton-transporting two-sector ATPase complex 1 GO:0007635 56 1 3.2597e-01 biological_process chemosensory behavior 1 GO:0006084 49 4 4.2332e-04 biological_process acetyl-CoA metabolism 1 1 1 1 GO:0006082 394 13 4.1268e-06 biological_process organic acid metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0030097 64 0 1.0000e+00 biological_process hemopoiesis GO:0031326 80 2 1.0926e-01 biological_process regulation of cellular biosynthesis 1 1 GO:0031325 69 0 1.0000e+00 biological_process positive regulation of cellular metabolism GO:0031324 145 0 1.0000e+00 biological_process negative regulation of cellular metabolism GO:0031323 1005 5 8.4313e-01 biological_process regulation of cellular metabolism 1 1 1 1 1 GO:0005759 148 6 6.5357e-04 cellular_component mitochondrial matrix 1 1 1 1 1 1 GO:0005575 5903 46 2.0443e-01 cellular_component cellular_component 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0005578 46 0 1.0000e+00 cellular_component extracellular matrix (sensu Metazoa) GO:0007591 32 0 1.0000e+00 biological_process molting cycle (sensu Insecta) GO:0001505 122 1 5.7747e-01 biological_process regulation of neurotransmitter levels 1 GO:0004620 41 0 1.0000e+00 molecular_function phospholipase activity GO:0000904 173 0 1.0000e+00 biological_process cellular morphogenesis during differentiation GO:0000902 350 2 7.0847e-01 biological_process cellular morphogenesis 1 1 GO:0043413 83 1 4.4304e-01 biological_process biopolymer glycosylation 1 GO:0015674 40 0 1.0000e+00 biological_process di-, tri-valent inorganic cation transport GO:0015672 179 1 7.1823e-01 biological_process monovalent inorganic cation transport 1 GO:0015926 31 0 1.0000e+00 molecular_function glucosidase activity GO:0016327 39 0 1.0000e+00 cellular_component apicolateral plasma membrane GO:0046930 41 0 1.0000e+00 cellular_component pore complex GO:0048599 84 0 1.0000e+00 biological_process oocyte development GO:0048592 152 0 1.0000e+00 biological_process eye morphogenesis GO:0006418 61 2 6.9084e-02 biological_process tRNA aminoacylation for protein translation 1 1 GO:0006417 76 2 1.0036e-01 biological_process regulation of protein biosynthesis 1 1 GO:0006144 55 2 5.7681e-02 biological_process purine base metabolism 1 1 GO:0008105 35 0 1.0000e+00 biological_process asymmetric protein localization GO:0008104 581 4 5.8735e-01 biological_process protein localization 1 1 1 1 GO:0046933 63 1 3.5847e-01 molecular_function hydrogen-transporting ATP synthase activity, rotational mechanism 1 GO:0004364 37 0 1.0000e+00 molecular_function glutathione transferase activity GO:0019897 36 0 1.0000e+00 cellular_component extrinsic to plasma membrane GO:0051179 2131 25 5.7976e-03 biological_process localization 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0009165 110 2 1.8131e-01 biological_process nucleotide biosynthesis 1 1 GO:0019318 81 0 1.0000e+00 biological_process hexose metabolism GO:0031966 188 8 5.8349e-05 cellular_component mitochondrial membrane 1 1 1 1 1 1 1 1 GO:0046552 43 0 1.0000e+00 biological_process photoreceptor cell fate commitment GO:0007046 30 0 1.0000e+00 biological_process ribosome biogenesis GO:0007049 483 6 1.2521e-01 biological_process cell cycle 1 1 1 1 1 1 GO:0043473 40 0 1.0000e+00 biological_process pigmentation GO:0008380 158 0 1.0000e+00 biological_process RNA splicing GO:0016407 49 1 2.9184e-01 molecular_function acetyltransferase activity 1 GO:0006066 163 0 1.0000e+00 biological_process alcohol metabolism GO:0006796 615 7 1.4231e-01 biological_process phosphate metabolism 1 1 1 1 1 1 1 GO:0006790 60 1 3.4474e-01 biological_process sulfur metabolism 1 GO:0005773 54 1 3.1639e-01 cellular_component vacuole 1 GO:0005777 35 0 1.0000e+00 cellular_component peroxisome GO:0001584 228 0 1.0000e+00 molecular_function rhodopsin-like receptor activity GO:0007530 45 0 1.0000e+00 biological_process sex determination GO:0006952 516 3 7.0755e-01 biological_process defense response 1 1 1 GO:0006950 340 2 6.9324e-01 biological_process response to stress 1 1 GO:0006955 123 2 2.1439e-01 biological_process immune response 1 1 GO:0004601 32 0 1.0000e+00 molecular_function peroxidase activity GO:0007389 264 0 1.0000e+00 biological_process pattern specification GO:0015698 54 0 1.0000e+00 biological_process inorganic anion transport GO:0051649 648 4 6.7322e-01 biological_process establishment of cellular localization 1 1 1 1 GO:0051640 32 0 1.0000e+00 biological_process organelle localization GO:0051641 649 4 6.7441e-01 biological_process cellular localization 1 1 1 1 GO:0008527 56 0 1.0000e+00 molecular_function taste receptor activity GO:0009653 658 4 6.8495e-01 biological_process morphogenesis 1 1 1 1 GO:0008528 52 0 1.0000e+00 molecular_function peptide receptor activity, G-protein coupled GO:0048519 298 2 6.2219e-01 biological_process negative regulation of biological process 1 1 GO:0006041 72 0 1.0000e+00 biological_process glucosamine metabolism GO:0019199 52 0 1.0000e+00 molecular_function transmembrane receptor protein kinase activity