##Ngenes: 13656 Nprom: 308 ##GOterm total hits pval process GO:0043283 1705 81 4.5396e-11 biological_process biopolymer metabolism GO:0006259 377 33 5.4142e-11 biological_process DNA metabolism GO:0006139 1796 83 9.5023e-11 biological_process nucleobase, nucleoside, nucleotide and nucleic acid metabolism GO:0051276 174 19 2.6890e-08 biological_process chromosome organization and biogenesis GO:0007001 159 18 3.6894e-08 biological_process chromosome organization and biogenesis (sensu Eukaryota) GO:0007059 127 16 5.1326e-08 biological_process chromosome segregation GO:0051244 1321 60 1.3781e-07 biological_process regulation of cellular physiological process GO:0050791 1364 61 1.8077e-07 biological_process regulation of physiological process GO:0050794 1404 62 2.1713e-07 biological_process regulation of cellular process GO:0000279 296 23 4.0148e-07 biological_process M phase GO:0050789 1531 65 4.1833e-07 biological_process regulation of biological process GO:0007049 483 30 7.5828e-07 biological_process cell cycle GO:0006281 112 13 2.2532e-06 biological_process DNA repair GO:0051321 95 12 2.3647e-06 biological_process meiotic cell cycle GO:0006396 258 20 2.4102e-06 biological_process RNA processing GO:0006974 121 13 5.1433e-06 biological_process response to DNA damage stimulus GO:0016070 372 24 5.4262e-06 biological_process RNA metabolism GO:0007126 90 11 8.4392e-06 biological_process meiosis GO:0051327 94 11 1.2581e-05 biological_process M phase of meiotic cell cycle GO:0006996 743 36 1.5871e-05 biological_process organelle organization and biogenesis GO:0006397 201 16 1.8013e-05 biological_process mRNA processing GO:0009719 137 13 1.8793e-05 biological_process response to endogenous stimulus GO:0006323 139 13 2.1804e-05 biological_process DNA packaging GO:0006325 139 13 2.1804e-05 biological_process establishment and/or maintenance of chromatin architecture GO:0006333 100 11 2.2071e-05 biological_process chromatin assembly or disassembly GO:0007067 232 17 2.7879e-05 biological_process mitosis GO:0000087 233 17 2.9398e-05 biological_process M phase of mitotic cell cycle GO:0016071 212 16 3.3892e-05 biological_process mRNA metabolism GO:0000375 152 13 5.3828e-05 biological_process RNA splicing, via transesterification reactions GO:0000377 152 13 5.3828e-05 biological_process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile GO:0000398 152 13 5.3828e-05 biological_process nuclear mRNA splicing, via spliceosome GO:0008380 158 13 7.9031e-05 biological_process RNA splicing GO:0019219 906 39 9.0455e-05 biological_process regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism GO:0048598 109 3 4.4595e-01 biological_process embryonic morphogenesis 1 1 1 GO:0030554 703 38 7.2013e-07 molecular_function adenyl nucleotide binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0051656 30 2 1.4760e-01 biological_process establishment of organelle localization 1 1 GO:0007626 74 1 8.1242e-01 biological_process locomotory behavior 1 GO:0007623 37 0 1.0000e+00 biological_process circadian rhythm GO:0006629 493 8 8.6899e-01 biological_process lipid metabolism 1 1 1 1 1 1 1 1 GO:0006626 36 0 1.0000e+00 biological_process protein targeting to mitochondrion GO:0008361 35 2 1.8730e-01 biological_process regulation of cell size 1 1 GO:0046467 31 2 1.5540e-01 biological_process membrane lipid biosynthesis 1 1 GO:0008360 87 4 1.3554e-01 biological_process regulation of cell shape 1 1 1 1 GO:0006974 121 13 5.1433e-06 biological_process response to DNA damage stimulus 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0004197 83 2 5.5901e-01 molecular_function cysteine-type endopeptidase activity 1 1 GO:0045449 847 32 3.2194e-03 biological_process regulation of transcription 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0051276 174 19 2.6890e-08 biological_process chromosome organization and biogenesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007369 59 1 7.3647e-01 biological_process gastrulation 1 GO:0050953 80 3 2.7038e-01 biological_process sensory perception of light stimulus 1 1 1 GO:0043231 2347 82 2.2410e-05 cellular_component intracellular membrane-bound organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0004806 37 0 1.0000e+00 molecular_function triacylglycerol lipase activity GO:0006367 85 4 1.2765e-01 biological_process transcription initiation from RNA polymerase II promoter 1 1 1 1 GO:0006366 694 27 4.5597e-03 biological_process transcription from RNA polymerase II promoter 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0016705 66 2 4.3874e-01 molecular_function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1 1 GO:0004857 128 2 7.8474e-01 molecular_function enzyme inhibitor activity 1 1 GO:0009056 330 8 4.6777e-01 biological_process catabolism 1 1 1 1 1 1 1 1 GO:0009057 192 8 7.1869e-02 biological_process macromolecule catabolism 1 1 1 1 1 1 1 1 GO:0048568 35 1 5.4634e-01 biological_process embryonic organ development 1 GO:0009055 54 0 1.0000e+00 molecular_function electron carrier activity GO:0005102 284 6 6.1925e-01 molecular_function receptor binding 1 1 1 1 1 2 GO:0009108 94 1 8.8086e-01 biological_process coenzyme biosynthesis 1 GO:0009109 49 0 1.0000e+00 biological_process coenzyme catabolism GO:0009100 88 2 5.9072e-01 biological_process glycoprotein metabolism 1 1 GO:0009101 85 2 5.7190e-01 biological_process glycoprotein biosynthesis 1 1 GO:0001738 58 2 3.7629e-01 biological_process morphogenesis of a polarized epithelium 1 1 GO:0042165 69 1 7.8990e-01 molecular_function neurotransmitter binding 1 GO:0001736 46 1 6.4628e-01 biological_process establishment of planar polarity 1 GO:0048037 39 0 1.0000e+00 molecular_function cofactor binding GO:0019953 472 20 5.7727e-03 biological_process sexual reproduction 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0016192 306 5 8.2096e-01 biological_process vesicle-mediated transport 1 1 1 1 1 GO:0003674 8432 193 3.9434e-01 molecular_function molecular_function 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 GO:0003676 1776 70 2.0312e-06 molecular_function nucleic acid binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0003677 844 29 1.6709e-02 molecular_function DNA binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0003678 51 9 3.1719e-06 molecular_function DNA helicase activity 1 1 1 1 1 1 1 1 1 GO:0051327 94 11 1.2581e-05 biological_process M phase of meiotic cell cycle 1 1 1 1 1 1 1 1 1 1 2 GO:0005737 1511 31 7.3773e-01 cellular_component cytoplasm 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0005730 58 1 7.3043e-01 cellular_component nucleolus 1 GO:0005739 468 6 9.5392e-01 cellular_component mitochondrion 1 1 1 1 1 1 GO:0006644 76 2 5.1174e-01 biological_process phospholipid metabolism 1 1 GO:0006643 87 3 3.1306e-01 biological_process membrane lipid metabolism 1 1 1 GO:0030594 69 1 7.8990e-01 molecular_function neurotransmitter receptor activity 1 GO:0008757 61 2 4.0008e-01 molecular_function S-adenosylmethionine-dependent methyltransferase activity 1 1 GO:0006915 179 7 1.1321e-01 biological_process apoptosis 1 1 1 1 1 1 1 GO:0007349 30 0 1.0000e+00 biological_process cellularization GO:0017038 56 6 1.8773e-03 biological_process protein import 1 1 1 1 1 1 GO:0006120 36 0 1.0000e+00 biological_process mitochondrial electron transport, NADH to ubiquinone GO:0004872 586 6 9.9174e-01 molecular_function receptor activity 1 1 1 1 1 1 GO:0004871 1090 24 5.7911e-01 molecular_function signal transducer activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0007582 6940 173 3.4189e-02 biological_process physiological process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 GO:0005694 214 19 6.1269e-07 cellular_component chromosome 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0004252 262 3 9.3563e-01 molecular_function serine-type endopeptidase activity 1 1 1 GO:0051049 62 3 1.6577e-01 biological_process regulation of transport 1 1 1 GO:0048468 355 10 2.8257e-01 biological_process cell development 1 1 1 1 1 1 1 1 1 1 GO:0001754 78 3 2.5830e-01 biological_process eye photoreceptor cell differentiation 1 1 1 GO:0001751 75 3 2.4033e-01 biological_process eye photoreceptor cell differentiation (sensu Endopterygota) 1 1 1 GO:0001752 35 1 5.4634e-01 biological_process eye photoreceptor fate commitment (sensu Endopterygota) 1 GO:0016818 556 25 9.5862e-04 molecular_function hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0016810 91 0 1.0000e+00 molecular_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds GO:0016811 53 0 1.0000e+00 molecular_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides GO:0016817 556 25 9.5862e-04 molecular_function hydrolase activity, acting on acid anhydrides 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0048110 57 1 7.2426e-01 biological_process oocyte construction (sensu Insecta) 1 GO:0051189 60 0 1.0000e+00 biological_process prosthetic group metabolism GO:0048111 56 1 7.1794e-01 biological_process oocyte axis determination (sensu Insecta) 1 GO:0008565 76 5 3.0108e-02 molecular_function protein transporter activity 1 1 1 1 1 GO:0007601 80 3 2.7038e-01 biological_process visual perception 1 1 1 GO:0043412 892 27 7.5023e-02 biological_process biopolymer modification 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0007600 266 4 8.5137e-01 biological_process sensory perception 1 1 1 1 GO:0009966 106 2 6.9072e-01 biological_process regulation of signal transduction 1 1 GO:0007602 32 0 1.0000e+00 biological_process phototransduction GO:0050877 636 10 9.1118e-01 biological_process neurophysiological process 1 1 1 1 1 1 1 1 1 2 GO:0050874 930 11 9.9491e-01 biological_process organismal physiological process 1 1 1 1 1 1 1 1 1 1 2 GO:0035282 128 5 1.6526e-01 biological_process segmentation 1 1 1 1 1 GO:0006936 93 0 1.0000e+00 biological_process muscle contraction GO:0000790 49 6 9.5956e-04 cellular_component nuclear chromatin 1 1 1 1 1 1 GO:0051187 50 0 1.0000e+00 biological_process cofactor catabolism GO:0051186 254 2 9.7894e-01 biological_process cofactor metabolism 1 1 GO:0019098 59 1 7.3647e-01 biological_process reproductive behavior 1 GO:0019094 38 1 5.7610e-01 biological_process pole plasm mRNA localization 1 GO:0051234 2068 31 9.9643e-01 biological_process establishment of localization 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007224 32 0 1.0000e+00 biological_process smoothened signaling pathway GO:0019899 55 3 1.2907e-01 molecular_function enzyme binding 1 1 1 GO:0019898 45 0 1.0000e+00 cellular_component extrinsic to membrane GO:0044271 85 0 1.0000e+00 biological_process nitrogen compound biosynthesis GO:0007420 49 2 3.0293e-01 biological_process brain development 1 1 GO:0006325 139 13 2.1804e-05 biological_process establishment and/or maintenance of chromatin architecture 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0006323 139 13 2.1804e-05 biological_process DNA packaging 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0048518 207 8 9.9525e-02 biological_process positive regulation of biological process 1 1 1 1 1 1 1 1 GO:0005996 101 2 6.6514e-01 biological_process monosaccharide metabolism 1 1 GO:0009141 71 2 4.7601e-01 biological_process nucleoside triphosphate metabolism 1 1 GO:0009142 69 2 4.6128e-01 biological_process nucleoside triphosphate biosynthesis 1 1 GO:0006810 1832 27 9.9541e-01 biological_process transport 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0006865 46 0 1.0000e+00 biological_process amino acid transport GO:0008094 38 10 2.3960e-08 molecular_function DNA-dependent ATPase activity 1 1 1 1 1 1 1 1 1 1 GO:0008092 248 6 4.8795e-01 molecular_function cytoskeletal protein binding 1 1 1 1 1 1 GO:0016835 62 0 1.0000e+00 molecular_function carbon-oxygen lyase activity GO:0016836 56 0 1.0000e+00 molecular_function hydro-lyase activity GO:0016831 34 1 5.3597e-01 molecular_function carboxy-lyase activity 1 GO:0008233 668 14 6.4802e-01 molecular_function peptidase activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0003954 37 0 1.0000e+00 molecular_function NADH dehydrogenase activity GO:0008237 192 0 1.0000e+00 molecular_function metallopeptidase activity GO:0008236 298 5 8.0309e-01 molecular_function serine-type peptidase activity 1 1 1 1 1 GO:0046903 238 3 9.0508e-01 biological_process secretion 1 1 1 GO:0016485 30 0 1.0000e+00 biological_process protein processing GO:0016481 115 5 1.2085e-01 biological_process negative regulation of transcription 1 1 1 1 1 GO:0015020 35 0 1.0000e+00 molecular_function glucuronosyltransferase activity GO:0051726 200 13 7.3615e-04 biological_process regulation of cell cycle 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0030162 30 0 1.0000e+00 biological_process regulation of proteolysis GO:0030163 90 4 1.4772e-01 biological_process protein catabolism 1 1 1 1 GO:0043038 62 3 1.6577e-01 biological_process amino acid activation 1 1 1 GO:0043039 61 3 1.6035e-01 biological_process tRNA aminoacylation 1 1 1 GO:0005083 95 0 1.0000e+00 molecular_function small GTPase regulator activity GO:0005085 61 2 4.0008e-01 molecular_function guanyl-nucleotide exchange factor activity 1 1 GO:0000226 94 5 6.3482e-02 biological_process microtubule cytoskeleton organization and biogenesis 1 1 1 1 2 GO:0000228 73 10 8.2270e-06 cellular_component nuclear chromosome 1 1 1 1 1 1 1 1 1 1 GO:0004930 273 3 9.4636e-01 molecular_function G-protein coupled receptor activity 1 1 1 GO:0007242 546 12 5.7686e-01 biological_process intracellular signaling cascade 1 1 1 1 1 1 1 1 1 1 2 2 GO:0007300 32 1 5.1450e-01 biological_process nurse cell to oocyte transport (sensu Insecta) 1 GO:0007304 55 2 3.5213e-01 biological_process eggshell formation (sensu Insecta) 1 1 GO:0007306 42 2 2.4482e-01 biological_process insect chorion formation 1 1 GO:0007308 83 2 5.5901e-01 biological_process oocyte construction 1 1 GO:0007309 80 2 5.3915e-01 biological_process oocyte axis determination 1 1 GO:0031226 203 1 9.9008e-01 cellular_component intrinsic to plasma membrane 1 GO:0051169 67 6 4.4917e-03 biological_process nuclear transport 1 1 1 1 1 1 GO:0048102 72 1 8.0372e-01 biological_process autophagic cell death 1 GO:0005654 205 14 2.8663e-04 cellular_component nucleoplasm 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0017076 866 41 6.7151e-06 molecular_function purine nucleotide binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 GO:0050790 37 2 2.0358e-01 biological_process regulation of enzyme activity 1 1 GO:0009308 379 4 9.7242e-01 biological_process amine metabolism 1 1 1 1 GO:0009309 85 0 1.0000e+00 biological_process amine biosynthesis GO:0000003 518 21 7.6411e-03 biological_process reproduction 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007498 207 0 1.0000e+00 biological_process mesoderm development GO:0009199 69 1 7.8990e-01 biological_process ribonucleoside triphosphate metabolism 1 GO:0016853 91 3 3.3756e-01 molecular_function isomerase activity 1 1 1 GO:0008219 252 8 2.1214e-01 biological_process cell death 1 1 1 1 1 1 1 1 GO:0016614 120 0 1.0000e+00 molecular_function oxidoreductase activity, acting on CH-OH group of donors GO:0030695 137 2 8.1537e-01 molecular_function GTPase regulator activity 1 1 GO:0016616 85 0 1.0000e+00 molecular_function oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016209 37 0 1.0000e+00 molecular_function antioxidant activity GO:0051707 132 1 9.4979e-01 biological_process response to other organism 1 GO:0051705 56 1 7.1794e-01 biological_process behavioral interaction between organisms 1 GO:0051704 59 1 7.3647e-01 biological_process interaction between organisms 1 GO:0042995 30 0 1.0000e+00 cellular_component cell projection GO:0002165 351 11 1.7326e-01 biological_process larval or pupal development (sensu Insecta) 1 1 1 1 1 1 1 1 1 1 1 GO:0002164 45 3 8.2766e-02 biological_process larval development 1 1 1 GO:0006807 394 4 9.7836e-01 biological_process nitrogen compound metabolism 1 1 1 1 GO:0006800 67 1 7.8016e-01 biological_process oxygen and reactive oxygen species metabolism 1 GO:0006512 191 7 1.4372e-01 biological_process ubiquitin cycle 1 1 1 1 1 1 2 GO:0006511 75 4 9.1395e-02 biological_process ubiquitin-dependent protein catabolism 1 1 1 1 GO:0006519 295 4 9.0079e-01 biological_process amino acid and derivative metabolism 1 1 1 1 GO:0003743 56 0 1.0000e+00 molecular_function translation initiation factor activity GO:0005351 40 1 5.9485e-01 molecular_function sugar porter activity 1 GO:0015144 81 1 8.3996e-01 molecular_function carbohydrate transporter activity 1 GO:0048522 185 7 1.2800e-01 biological_process positive regulation of cellular process 1 1 1 1 1 1 1 GO:0004004 40 2 2.2826e-01 molecular_function ATP-dependent RNA helicase activity 1 1 GO:0007269 110 0 1.0000e+00 biological_process neurotransmitter secretion GO:0007268 233 3 8.9726e-01 biological_process synaptic transmission 1 1 2 GO:0007267 463 6 9.5069e-01 biological_process cell-cell signaling 1 1 1 1 1 2 GO:0007264 119 5 1.3386e-01 biological_process small GTPase mediated signal transduction 1 1 1 1 2 GO:0006886 518 16 1.2928e-01 biological_process intracellular protein transport 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0031224 972 12 9.9362e-01 cellular_component intrinsic to membrane 1 1 1 1 1 1 1 1 1 1 1 1 GO:0018988 35 0 1.0000e+00 biological_process molting cycle (sensu Protostomia and Nematoda) GO:0016055 58 0 1.0000e+00 biological_process Wnt receptor signaling pathway GO:0016052 68 2 4.5383e-01 biological_process carbohydrate catabolism 1 1 GO:0016053 31 0 1.0000e+00 biological_process organic acid biosynthesis GO:0016051 50 0 1.0000e+00 biological_process carbohydrate biosynthesis GO:0043229 2736 90 7.6744e-05 cellular_component intracellular organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0043227 2349 82 2.3118e-05 cellular_component membrane-bound organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0043226 2737 90 7.7791e-05 cellular_component organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0048731 653 16 4.0335e-01 biological_process system development 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0031980 148 2 8.4747e-01 cellular_component mitochondrial lumen 1 1 GO:0042775 62 0 1.0000e+00 biological_process ATP synthesis coupled electron transport (sensu Eukaryota) GO:0048736 136 5 1.9538e-01 biological_process appendage development 1 1 1 1 1 GO:0048737 133 5 1.8386e-01 biological_process appendage development (sensu Endopterygota) 1 1 1 1 1 GO:0015837 46 0 1.0000e+00 biological_process amine transport GO:0005634 1565 74 5.1445e-10 cellular_component nucleus 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0005635 65 5 1.6754e-02 cellular_component nuclear envelope 1 1 1 1 1 GO:0009987 6819 179 2.3988e-03 biological_process cellular process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 GO:0045132 37 2 2.0358e-01 biological_process meiotic chromosome segregation 1 1 GO:0005184 33 0 1.0000e+00 molecular_function neuropeptide hormone activity GO:0009187 37 0 1.0000e+00 biological_process cyclic nucleotide metabolism GO:0005792 83 0 1.0000e+00 cellular_component microsome GO:0000315 46 1 6.4628e-01 cellular_component organellar large ribosomal subunit 1 GO:0000313 75 2 5.0472e-01 cellular_component organellar ribosome 1 1 GO:0016874 319 11 1.1037e-01 molecular_function ligase activity 1 1 1 1 1 1 1 1 1 1 2 GO:0016875 60 3 1.5498e-01 molecular_function ligase activity, forming carbon-oxygen bonds 1 1 1 GO:0016876 60 3 1.5498e-01 molecular_function ligase activity, forming aminoacyl-tRNA and related compounds 1 1 1 GO:0000070 32 5 8.7817e-04 biological_process mitotic sister chromatid segregation 1 1 1 1 1 GO:0000074 200 13 7.3615e-04 biological_process regulation of progression through cell cycle 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0001871 80 0 1.0000e+00 molecular_function pattern binding GO:0007409 124 2 7.6976e-01 biological_process axonogenesis 1 1 GO:0006044 72 0 1.0000e+00 biological_process N-acetylglucosamine metabolism GO:0019932 90 1 8.6953e-01 biological_process second-messenger-mediated signaling 1 GO:0016265 299 8 3.6273e-01 biological_process death 1 1 1 1 1 1 1 1 GO:0016706 33 1 5.2536e-01 molecular_function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 1 GO:0045892 101 5 8.0461e-02 biological_process negative regulation of transcription, DNA-dependent 1 1 1 1 1 GO:0045893 49 2 3.0293e-01 biological_process positive regulation of transcription, DNA-dependent 1 1 GO:0003724 59 3 1.4967e-01 molecular_function RNA helicase activity 1 1 1 GO:0003723 376 14 4.8191e-02 molecular_function RNA binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0003729 318 11 1.0865e-01 molecular_function mRNA binding 1 1 1 1 1 1 1 1 1 1 1 GO:0000267 96 0 1.0000e+00 cellular_component cell fraction GO:0007281 118 4 2.7709e-01 biological_process germ cell development 1 1 1 1 GO:0007283 115 5 1.2085e-01 biological_process spermatogenesis 1 1 1 1 1 GO:0007286 40 2 2.2826e-01 biological_process spermatid development 1 1 GO:0006887 128 3 5.5198e-01 biological_process exocytosis 1 1 1 GO:0008643 81 1 8.3996e-01 biological_process carbohydrate transport 1 GO:0016070 372 24 5.4262e-06 biological_process RNA metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0016071 212 16 3.3892e-05 biological_process mRNA metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0016072 43 1 6.2143e-01 biological_process rRNA metabolism 1 GO:0016079 48 0 1.0000e+00 biological_process synaptic vesicle exocytosis GO:0008509 95 1 8.8353e-01 molecular_function anion transporter activity 1 GO:0045165 197 7 1.6031e-01 biological_process cell fate commitment 1 1 1 1 1 1 2 GO:0050791 1364 61 1.8077e-07 biological_process regulation of physiological process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0030534 47 2 2.8636e-01 biological_process adult behavior 1 1 GO:0030532 62 7 5.9162e-04 cellular_component small nuclear ribonucleoprotein complex 1 1 1 1 1 1 1 GO:0043065 65 3 1.8236e-01 biological_process positive regulation of apoptosis 1 1 1 GO:0006869 59 4 4.5845e-02 biological_process lipid transport 1 1 1 1 GO:0004702 179 10 8.1889e-03 molecular_function receptor signaling protein serine/threonine kinase activity 1 1 1 1 1 1 1 2 2 2 GO:0007548 52 1 6.9120e-01 biological_process sex differentiation 1 GO:0015267 186 1 9.8536e-01 molecular_function channel or pore class transporter activity 1 GO:0015268 186 1 9.8536e-01 molecular_function alpha-type channel activity 1 GO:0016791 183 3 7.8195e-01 molecular_function phosphoric monoester hydrolase activity 1 1 1 GO:0016790 34 1 5.3597e-01 molecular_function thiolester hydrolase activity 1 GO:0016799 42 0 1.0000e+00 molecular_function hydrolase activity, hydrolyzing N-glycosyl compounds GO:0050875 6312 167 2.9427e-03 biological_process cellular physiological process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 GO:0006412 502 12 4.5985e-01 biological_process protein biosynthesis 1 1 1 1 1 1 1 1 1 1 1 1 GO:0030182 153 3 6.7150e-01 biological_process neuron differentiation 1 1 1 GO:0017111 530 25 4.8895e-04 molecular_function nucleoside-triphosphatase activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0042221 269 3 9.4267e-01 biological_process response to chemical stimulus 1 1 2 GO:0046698 257 10 6.8743e-02 biological_process metamorphosis (sensu Insecta) 1 1 1 1 1 1 1 1 1 1 GO:0007431 110 1 9.1717e-01 biological_process salivary gland development 1 GO:0031589 31 1 5.0340e-01 biological_process cell-substrate adhesion 1 GO:0007424 112 5 1.1151e-01 biological_process tracheal system development (sensu Insecta) 1 1 1 1 1 GO:0016798 108 1 9.1332e-01 molecular_function hydrolase activity, acting on glycosyl bonds 1 GO:0009063 49 0 1.0000e+00 biological_process amino acid catabolism GO:0009060 48 0 1.0000e+00 biological_process aerobic respiration GO:0007423 79 1 8.3253e-01 biological_process sensory organ development 1 GO:0009611 34 0 1.0000e+00 biological_process response to wounding GO:0007422 143 5 2.2316e-01 biological_process peripheral nervous system development 1 1 1 1 1 GO:0000819 32 5 8.7817e-04 biological_process sister chromatid segregation 1 1 1 1 1 GO:0007507 63 0 1.0000e+00 biological_process heart development GO:0050794 1404 62 2.1713e-07 biological_process regulation of cellular process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0005941 74 1 8.1242e-01 cellular_component unlocalized protein complex 1 GO:0006766 36 1 5.5648e-01 biological_process vitamin metabolism 1 GO:0044257 82 4 1.1621e-01 biological_process cellular protein catabolism 1 1 1 1 GO:0044255 337 5 8.7822e-01 biological_process cellular lipid metabolism 1 1 1 1 1 GO:0000381 50 6 1.0632e-03 biological_process regulation of alternative nuclear mRNA splicing, via spliceosome 1 1 1 1 1 1 GO:0000380 51 6 1.1753e-03 biological_process alternative nuclear mRNA splicing, via spliceosome 1 1 1 1 1 1 GO:0004540 44 3 7.8609e-02 molecular_function ribonuclease activity 1 1 1 GO:0008017 76 2 5.1174e-01 molecular_function microtubule binding 1 1 GO:0008010 40 0 1.0000e+00 molecular_function structural constituent of larval cuticle (sensu Insecta) GO:0004725 31 1 5.0340e-01 molecular_function protein tyrosine phosphatase activity 1 GO:0004722 39 0 1.0000e+00 molecular_function protein serine/threonine phosphatase activity GO:0004721 89 2 5.9686e-01 molecular_function phosphoprotein phosphatase activity 1 1 GO:0015203 39 0 1.0000e+00 molecular_function polyamine transporter activity GO:0019201 32 1 5.1450e-01 molecular_function nucleotide kinase activity 1 GO:0019204 36 1 5.5648e-01 molecular_function nucleotide phosphatase activity 1 GO:0019205 34 1 5.3597e-01 molecular_function nucleobase, nucleoside, nucleotide kinase activity 1 GO:0019208 32 1 5.1450e-01 molecular_function phosphatase regulator activity 1 GO:0019752 394 3 9.9371e-01 biological_process carboxylic acid metabolism 1 1 1 GO:0007155 316 7 5.7099e-01 biological_process cell adhesion 1 1 1 1 1 1 1 GO:0007154 1567 32 7.5007e-01 biological_process cell communication 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0006575 49 1 6.6950e-01 biological_process amino acid derivative metabolism 1 GO:0006576 30 1 4.9205e-01 biological_process biogenic amine metabolism 1 GO:0015992 78 1 8.2869e-01 biological_process proton transport 1 GO:0009260 91 1 8.7246e-01 biological_process ribonucleotide biosynthesis 1 GO:0009266 55 1 7.1148e-01 biological_process response to temperature stimulus 1 GO:0050793 82 2 5.5246e-01 biological_process regulation of development 1 1 GO:0030703 55 2 3.5213e-01 biological_process eggshell formation 1 1 GO:0030707 126 6 6.7917e-02 biological_process ovarian follicle cell development (sensu Insecta) 1 1 1 1 1 1 GO:0030705 104 3 4.1637e-01 biological_process cytoskeleton-dependent intracellular transport 1 1 1 GO:0008652 73 0 1.0000e+00 biological_process amino acid biosynthesis GO:0001654 185 6 2.4146e-01 biological_process eye development 1 1 1 1 1 1 GO:0008354 33 0 1.0000e+00 biological_process germ cell migration GO:0035071 72 1 8.0372e-01 biological_process salivary gland cell autophagic cell death 1 GO:0019001 166 4 5.1593e-01 molecular_function guanyl nucleotide binding 1 1 1 2 GO:0046983 50 1 6.7690e-01 molecular_function protein dimerization activity 1 GO:0040011 271 4 8.6115e-01 biological_process locomotion 1 1 1 1 GO:0048729 46 0 1.0000e+00 biological_process tissue morphogenesis GO:0005829 185 3 7.8809e-01 cellular_component cytosol 1 1 1 GO:0006916 38 1 5.7610e-01 biological_process anti-apoptosis 1 GO:0006917 63 3 1.7125e-01 biological_process induction of apoptosis 1 1 1 GO:0006457 131 2 7.9542e-01 biological_process protein folding 1 1 GO:0004527 41 3 6.6714e-02 molecular_function exonuclease activity 1 1 1 GO:0005214 82 0 1.0000e+00 molecular_function structural constituent of cuticle (sensu Insecta) GO:0005215 982 15 9.6068e-01 molecular_function transporter activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0005216 168 1 9.7791e-01 molecular_function ion channel activity 1 GO:0004295 235 2 9.6953e-01 molecular_function trypsin activity 1 1 GO:0008298 50 2 3.1119e-01 biological_process intracellular mRNA localization 1 1 GO:0008293 33 1 5.2536e-01 biological_process torso signaling pathway 1 GO:0019226 377 6 8.5429e-01 biological_process transmission of nerve impulse 1 1 1 1 1 2 GO:0019221 33 1 5.2536e-01 biological_process cytokine and chemokine mediated signaling pathway 1 GO:0019730 64 1 7.6469e-01 biological_process antimicrobial humoral response 1 GO:0019731 38 1 5.7610e-01 biological_process antibacterial humoral response 1 GO:0007173 39 2 2.2000e-01 biological_process epidermal growth factor receptor signaling pathway 1 1 GO:0007179 30 0 1.0000e+00 biological_process transforming growth factor beta receptor signaling pathway GO:0007178 52 1 6.9120e-01 biological_process transmembrane receptor protein serine/threonine kinase signaling pathway 1 GO:0016757 162 2 8.8099e-01 molecular_function transferase activity, transferring glycosyl groups 1 1 GO:0016758 132 2 7.9887e-01 molecular_function transferase activity, transferring hexosyl groups 1 1 GO:0016283 39 1 5.8558e-01 cellular_component eukaryotic 48S initiation complex 1 GO:0016282 60 1 7.4237e-01 cellular_component eukaryotic 43S preinitiation complex 1 GO:0044270 52 0 1.0000e+00 biological_process nitrogen compound catabolism GO:0012501 250 8 2.0631e-01 biological_process programmed cell death 1 1 1 1 1 1 1 1 GO:0012502 71 3 2.1672e-01 biological_process induction of programmed cell death 1 1 1 GO:0012505 150 5 2.5205e-01 cellular_component endomembrane system 1 1 1 1 1 GO:0012506 32 0 1.0000e+00 cellular_component vesicle membrane GO:0031012 46 0 1.0000e+00 cellular_component extracellular matrix GO:0042773 63 0 1.0000e+00 biological_process ATP synthesis coupled electron transport GO:0043632 77 4 9.8201e-02 biological_process modification-dependent macromolecule catabolism 1 1 1 1 GO:0017157 46 2 2.7805e-01 biological_process regulation of exocytosis 1 1 GO:0008194 93 2 6.2072e-01 molecular_function UDP-glycosyltransferase activity 1 1 GO:0004888 451 5 9.7556e-01 molecular_function transmembrane receptor activity 1 1 1 1 1 GO:0006820 100 1 8.9604e-01 biological_process anion transport 1 GO:0008372 844 10 9.9278e-01 cellular_component cellular component unknown 1 1 1 1 1 1 1 1 1 1 GO:0005840 190 3 8.0281e-01 cellular_component ribosome 1 1 1 GO:0005843 39 1 5.8558e-01 cellular_component cytosolic small ribosomal subunit (sensu Eukaryota) 1 GO:0005842 52 0 1.0000e+00 cellular_component cytosolic large ribosomal subunit (sensu Eukaryota) GO:0030001 151 0 1.0000e+00 biological_process metal ion transport GO:0005976 163 0 1.0000e+00 biological_process polysaccharide metabolism GO:0003700 398 2 9.9887e-01 molecular_function transcription factor activity 1 1 GO:0003682 84 11 4.4488e-06 molecular_function chromatin binding 1 1 1 1 1 1 1 1 1 1 2 GO:0003702 273 5 7.3821e-01 molecular_function RNA polymerase II transcription factor activity 1 1 1 1 1 GO:0003704 82 1 8.4355e-01 molecular_function specific RNA polymerase II transcription factor activity 1 GO:0048193 37 0 1.0000e+00 biological_process Golgi vesicle transport GO:0005279 39 0 1.0000e+00 molecular_function amino acid-polyamine transporter activity GO:0016779 93 3 3.4979e-01 molecular_function nucleotidyltransferase activity 1 1 1 GO:0016773 365 15 2.0006e-02 molecular_function phosphotransferase activity, alcohol group as acceptor 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0016772 514 19 2.5555e-02 molecular_function transferase activity, transferring phosphorus-containing groups 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0042175 42 0 1.0000e+00 cellular_component nuclear envelope-endoplasmic reticulum network GO:0043565 35 2 1.8730e-01 molecular_function sequence-specific DNA binding 1 1 GO:0016829 160 2 8.7666e-01 molecular_function lyase activity 1 1 GO:0019866 175 2 9.0590e-01 cellular_component organelle inner membrane 1 1 GO:0006468 293 13 1.6928e-02 biological_process protein amino acid phosphorylation 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0006461 120 6 5.6438e-02 biological_process protein complex assembly 1 1 1 1 1 2 GO:0006464 849 25 1.0629e-01 biological_process protein modification 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0035070 72 1 8.0372e-01 biological_process salivary gland histolysis 1 GO:0007472 108 5 9.9620e-02 biological_process wing disc morphogenesis 1 1 1 1 1 GO:0007476 106 5 9.3929e-02 biological_process wing morphogenesis 1 1 1 1 1 GO:0008170 36 1 5.5648e-01 molecular_function N-methyltransferase activity 1 GO:0000151 126 4 3.1722e-01 cellular_component ubiquitin ligase complex 1 1 1 1 GO:0016125 34 0 1.0000e+00 biological_process sterol metabolism GO:0030247 67 0 1.0000e+00 molecular_function polysaccharide binding GO:0030246 114 0 1.0000e+00 molecular_function carbohydrate binding GO:0030029 102 3 4.0440e-01 biological_process actin filament-based process 1 1 1 GO:0006259 377 33 5.4142e-11 biological_process DNA metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0005783 117 0 1.0000e+00 cellular_component endoplasmic reticulum GO:0005789 41 0 1.0000e+00 cellular_component endoplasmic reticulum membrane GO:0009968 49 1 6.6950e-01 biological_process negative regulation of signal transduction 1 GO:0048732 132 4 3.4762e-01 biological_process gland development 1 1 1 1 GO:0043170 3151 107 2.3257e-06 biological_process macromolecule metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 GO:0005529 48 0 1.0000e+00 molecular_function sugar binding GO:0005524 686 38 3.9896e-07 molecular_function ATP binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0005525 165 4 5.1122e-01 molecular_function GTP binding 1 1 1 2 GO:0007456 177 6 2.1260e-01 biological_process eye development (sensu Endopterygota) 1 1 1 1 1 1 GO:0015629 75 3 2.4033e-01 cellular_component actin cytoskeleton 1 1 1 GO:0046907 629 17 2.5659e-01 biological_process intracellular transport 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0044238 4617 136 1.0408e-04 biological_process primary metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 GO:0009206 68 1 7.8509e-01 biological_process purine ribonucleoside triphosphate biosynthesis 1 GO:0009205 69 1 7.8990e-01 biological_process purine ribonucleoside triphosphate metabolism 1 GO:0009201 68 1 7.8509e-01 biological_process ribonucleoside triphosphate biosynthesis 1 GO:0006445 73 2 4.9049e-01 biological_process regulation of translation 1 1 GO:0048534 74 3 2.3438e-01 biological_process hemopoietic or lymphoid organ development 1 1 1 GO:0048637 43 0 1.0000e+00 biological_process skeletal muscle development GO:0007559 73 1 8.0812e-01 biological_process histolysis 1 GO:0008150 8219 193 2.0375e-01 biological_process biological_process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 GO:0008152 5111 138 4.7586e-03 biological_process metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 GO:0031410 89 0 1.0000e+00 cellular_component cytoplasmic vesicle GO:0007606 168 1 9.7791e-01 biological_process sensory perception of chemical stimulus 1 GO:0045595 44 1 6.2990e-01 biological_process regulation of cell differentiation 1 GO:0044237 4680 131 1.5736e-03 biological_process cellular metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 GO:0015101 30 0 1.0000e+00 molecular_function organic cation transporter activity GO:0015103 40 0 1.0000e+00 molecular_function inorganic anion transporter activity GO:0005887 201 1 9.8961e-01 cellular_component integral to plasma membrane 1 GO:0005886 550 10 7.9668e-01 cellular_component plasma membrane 1 1 1 1 1 1 1 1 1 2 GO:0007015 64 2 4.2343e-01 biological_process actin filament organization 1 1 GO:0007017 203 8 9.1632e-02 biological_process microtubule-based process 1 1 1 1 1 1 2 2 GO:0007010 464 14 1.6811e-01 biological_process cytoskeleton organization and biogenesis 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0007018 103 3 4.1040e-01 biological_process microtubule-based movement 1 1 1 GO:0016458 45 6 6.2020e-04 biological_process gene silencing 1 1 1 1 1 1 GO:0009887 344 12 9.2579e-02 biological_process organ morphogenesis 1 1 1 1 1 1 1 1 1 1 1 1 GO:0031175 146 2 8.4204e-01 biological_process neurite development 1 1 GO:0009948 121 3 5.1426e-01 biological_process anterior/posterior axis specification 1 1 1 GO:0035239 66 2 4.3874e-01 biological_process tube morphogenesis 1 1 GO:0009416 49 0 1.0000e+00 biological_process response to light stimulus GO:0042051 45 2 2.6975e-01 biological_process eye photoreceptor development (sensu Endopterygota) 1 1 GO:0005509 222 2 9.6090e-01 molecular_function calcium ion binding 1 2 GO:0005506 43 0 1.0000e+00 molecular_function iron ion binding GO:0050909 60 1 7.4237e-01 biological_process sensory perception of taste 1 GO:0046942 55 0 1.0000e+00 biological_process carboxylic acid transport GO:0016591 85 4 1.2765e-01 cellular_component DNA-directed RNA polymerase II, holoenzyme 1 1 1 1 GO:0007467 90 3 3.3144e-01 biological_process photoreceptor cell differentiation (sensu Endopterygota) 1 1 1 GO:0048754 32 1 5.1450e-01 biological_process branching morphogenesis of a tube 1 GO:0019829 69 1 7.8990e-01 molecular_function cation-transporting ATPase activity 1 GO:0009880 131 4 3.4255e-01 biological_process embryonic pattern specification 1 1 1 1 GO:0009889 80 2 5.3915e-01 biological_process regulation of biosynthesis 1 1 GO:0009888 416 3 9.9583e-01 biological_process tissue development 1 1 1 GO:0035218 39 1 5.8558e-01 biological_process leg disc development 1 GO:0046148 41 0 1.0000e+00 biological_process pigment biosynthesis GO:0008134 92 6 1.9028e-02 molecular_function transcription factor binding 1 1 1 1 1 1 GO:0008135 84 0 1.0000e+00 molecular_function translation factor activity, nucleic acid binding GO:0048232 115 5 1.2085e-01 biological_process male gamete generation 1 1 1 1 1 GO:0045202 41 0 1.0000e+00 cellular_component synapse GO:0009628 380 5 9.3142e-01 biological_process response to abiotic stimulus 1 1 1 1 2 GO:0042440 48 0 1.0000e+00 biological_process pigment metabolism GO:0019888 32 1 5.1450e-01 molecular_function protein phosphatase regulator activity 1 GO:0016477 182 2 9.1721e-01 biological_process cell migration 1 1 GO:0042303 35 0 1.0000e+00 biological_process molting cycle GO:0042302 100 0 1.0000e+00 molecular_function structural constituent of cuticle GO:0043414 42 1 6.1277e-01 biological_process biopolymer methylation 1 GO:0003712 76 6 8.1063e-03 molecular_function transcription cofactor activity 1 1 1 1 1 1 GO:0005743 170 2 8.9696e-01 cellular_component mitochondrial inner membrane 1 1 GO:0005740 206 2 9.4703e-01 cellular_component mitochondrial envelope 1 1 GO:0005746 70 0 1.0000e+00 cellular_component mitochondrial electron transport chain GO:0005747 38 0 1.0000e+00 cellular_component respiratory chain complex I (sensu Eukaryota) GO:0000910 89 5 5.2724e-02 biological_process cytokinesis 1 1 1 1 1 GO:0048747 43 0 1.0000e+00 biological_process muscle fiber development GO:0051252 57 7 3.6109e-04 biological_process regulation of RNA metabolism 1 1 1 1 1 1 1 GO:0015662 74 2 4.9764e-01 molecular_function ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 1 1 GO:0015931 37 3 5.2272e-02 biological_process nucleobase, nucleoside, nucleotide and nucleic acid transport 1 1 1 GO:0015934 97 1 8.8870e-01 cellular_component large ribosomal subunit 1 GO:0015935 69 2 4.6128e-01 cellular_component small ribosomal subunit 1 1 GO:0016311 110 1 9.1717e-01 biological_process dephosphorylation 1 GO:0016310 470 15 1.1464e-01 biological_process phosphorylation 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0046164 51 2 3.1943e-01 biological_process alcohol catabolism 1 1 GO:0030414 87 1 8.6033e-01 molecular_function protease inhibitor activity 1 GO:0048489 85 0 1.0000e+00 biological_process synaptic vesicle transport GO:0006403 94 7 5.9597e-03 biological_process RNA localization 1 1 1 1 1 1 1 GO:0005179 52 0 1.0000e+00 molecular_function hormone activity GO:0016491 631 6 9.9593e-01 molecular_function oxidoreductase activity 1 1 1 1 1 1 GO:0009607 524 5 9.9225e-01 biological_process response to biotic stimulus 1 1 1 1 1 GO:0009605 108 2 7.0050e-01 biological_process response to external stimulus 1 2 GO:0005230 53 0 1.0000e+00 molecular_function extracellular ligand-gated ion channel activity GO:0005231 48 0 1.0000e+00 molecular_function excitatory extracellular ligand-gated ion channel activity GO:0007051 30 2 1.4760e-01 biological_process spindle organization and biogenesis 1 1 GO:0007059 127 16 5.1326e-08 biological_process chromosome segregation 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0016410 33 1 5.2536e-01 molecular_function N-acyltransferase activity 1 GO:0006099 48 0 1.0000e+00 biological_process tricarboxylic acid cycle GO:0006092 105 2 6.8574e-01 biological_process main pathways of carbohydrate metabolism 1 1 GO:0006091 509 5 9.9013e-01 biological_process generation of precursor metabolites and energy 1 1 1 1 1 GO:0006096 39 1 5.8558e-01 biological_process glycolysis 1 GO:0048699 185 3 7.8809e-01 biological_process neurogenesis 1 1 1 GO:0005761 75 2 5.0472e-01 cellular_component mitochondrial ribosome 1 1 GO:0005762 46 1 6.4628e-01 cellular_component mitochondrial large ribosomal subunit 1 GO:0005763 30 1 4.9205e-01 cellular_component mitochondrial small ribosomal subunit 1 GO:0004497 110 1 9.1717e-01 molecular_function monooxygenase activity 1 GO:0007610 199 5 4.6635e-01 biological_process behavior 1 1 1 1 1 GO:0005549 117 0 1.0000e+00 molecular_function odorant binding GO:0051242 163 7 7.8528e-02 biological_process positive regulation of cellular physiological process 1 1 1 1 1 1 1 GO:0008270 613 19 1.0288e-01 molecular_function zinc ion binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0051244 1321 60 1.3781e-07 biological_process regulation of cellular physiological process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0016331 85 2 5.7190e-01 biological_process morphogenesis of embryonic epithelium 1 1 GO:0016337 133 0 1.0000e+00 biological_process cell-cell adhesion GO:0046365 51 2 3.1943e-01 biological_process monosaccharide catabolism 1 1 GO:0035114 133 5 1.8386e-01 biological_process appendage morphogenesis (sensu Endopterygota) 1 1 1 1 1 GO:0006399 89 4 1.4361e-01 biological_process tRNA metabolism 1 1 1 1 GO:0048523 271 7 4.1189e-01 biological_process negative regulation of cellular process 1 1 1 1 1 1 1 GO:0043296 34 3 4.2564e-02 cellular_component apical junction complex 1 1 1 GO:0006396 258 20 2.4102e-06 biological_process RNA processing 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0006397 201 16 1.8013e-05 biological_process mRNA processing 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0044275 68 2 4.5383e-01 biological_process cellular carbohydrate catabolism 1 1 GO:0007411 88 1 8.6347e-01 biological_process axon guidance 1 GO:0045184 534 16 1.5444e-01 biological_process establishment of protein localization 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0045182 88 0 1.0000e+00 molecular_function translation regulator activity GO:0007568 48 0 1.0000e+00 biological_process aging GO:0007560 246 10 5.4650e-02 biological_process imaginal disc morphogenesis 1 1 1 1 1 1 1 1 1 1 GO:0016301 412 16 2.6275e-02 molecular_function kinase activity 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0048749 136 5 1.9538e-01 biological_process compound eye development (sensu Endopterygota) 1 1 1 1 1 GO:0019200 33 0 1.0000e+00 molecular_function carbohydrate kinase activity GO:0019207 67 2 4.4631e-01 molecular_function kinase regulator activity 1 1 GO:0001708 56 0 1.0000e+00 biological_process cell fate specification GO:0001709 112 4 2.4759e-01 biological_process cell fate determination 1 1 1 1 GO:0045935 67 2 4.4631e-01 biological_process positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 1 GO:0016651 44 0 1.0000e+00 molecular_function oxidoreductase activity, acting on NADH or NADPH GO:0043228 745 31 8.5688e-04 cellular_component non-membrane-bound organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0040008 62 2 4.0791e-01 biological_process regulation of growth 1 1 GO:0005700 48 3 9.5784e-02 cellular_component polytene chromosome 1 1 1 GO:0048589 40 0 1.0000e+00 biological_process developmental growth GO:0045045 222 3 8.7800e-01 biological_process secretory pathway 1 1 1 GO:0045451 33 0 1.0000e+00 biological_process pole plasm oskar mRNA localization GO:0007399 530 12 5.3527e-01 biological_process nervous system development 1 1 1 1 1 1 1 1 1 1 1 1 GO:0007398 249 2 9.7678e-01 biological_process ectoderm development 1 1 GO:0007391 77 1 8.2476e-01 biological_process dorsal closure 1 GO:0016358 37 0 1.0000e+00 biological_process dendrite development GO:0046961 63 1 7.5930e-01 molecular_function hydrogen-transporting ATPase activity, rotational mechanism 1 GO:0048565 63 1 7.5930e-01 biological_process gut development 1 GO:0048567 40 1 5.9485e-01 biological_process ectodermal gut morphogenesis 1 GO:0006118 336 2 9.9592e-01 biological_process electron transport 1 1 GO:0006119 142 1 9.6002e-01 biological_process oxidative phosphorylation 1 GO:0004842 139 5 2.0714e-01 molecular_function ubiquitin-protein ligase activity 1 1 1 1 2 GO:0004843 30 1 4.9205e-01 molecular_function ubiquitin-specific protease activity 1 GO:0004840 33 1 5.2536e-01 molecular_function ubiquitin conjugating enzyme activity 1 GO:0031497 51 7 1.8578e-04 biological_process chromatin assembly 1 1 1 1 1 1 2 GO:0004263 208 2 9.4899e-01 molecular_function chymotrypsin activity 1 1 GO:0007400 30 0 1.0000e+00 biological_process neuroblast fate determination GO:0003899 31 0 1.0000e+00 molecular_function DNA-directed RNA polymerase activity GO:0006281 112 13 2.2532e-06 biological_process DNA repair 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0007186 320 3 9.7602e-01 biological_process G-protein coupled receptor protein signaling pathway 1 1 1 GO:0006631 103 0 1.0000e+00 biological_process fatty acid metabolism GO:0046943 72 0 1.0000e+00 molecular_function carboxylic acid transporter activity GO:0004984 63 0 1.0000e+00 molecular_function olfactory receptor activity GO:0006960 45 0 1.0000e+00 biological_process antimicrobial humoral response (sensu Protostomia) GO:0005554 784 12 9.4216e-01 molecular_function molecular function unknown 1 1 1 1 1 1 1 1 1 1 1 2 GO:0004182 32 0 1.0000e+00 molecular_function carboxypeptidase A activity GO:0004181 32 0 1.0000e+00 molecular_function metallocarboxypeptidase activity GO:0004180 43 2 2.5313e-01 molecular_function carboxypeptidase activity 1 1 GO:0004674 215 13 1.4012e-03 molecular_function protein serine/threonine kinase activity 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0004672 303 14 9.7888e-03 molecular_function protein kinase activity 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0007218 32 0 1.0000e+00 biological_process neuropeptide signaling pathway GO:0007219 41 1 6.0391e-01 biological_process Notch signaling pathway 1 GO:0046873 32 0 1.0000e+00 molecular_function metal ion transporter activity GO:0046872 947 23 3.8746e-01 molecular_function metal ion binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0035214 163 6 1.6541e-01 biological_process eye-antennal disc development 1 1 1 1 1 1 GO:0051674 266 3 9.3974e-01 biological_process localization of cell 1 1 1 GO:0006355 802 31 2.6655e-03 biological_process regulation of transcription, DNA-dependent 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0006357 558 19 5.0912e-02 biological_process regulation of transcription from RNA polymerase II promoter 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0006350 962 39 3.0404e-04 biological_process transcription 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0006351 912 38 2.1463e-04 biological_process transcription, DNA-dependent 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0006352 87 4 1.3554e-01 biological_process transcription initiation 1 1 1 1 GO:0009617 74 1 8.1242e-01 biological_process response to bacteria 1 GO:0042578 201 4 6.6520e-01 molecular_function phosphoric ester hydrolase activity 1 1 1 1 GO:0042579 35 1 5.4634e-01 cellular_component microbody 1 GO:0006139 1796 83 9.5023e-11 biological_process nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0048113 43 1 6.2143e-01 biological_process pole plasm assembly (sensu Insecta) 1 GO:0004866 86 1 8.5713e-01 molecular_function endopeptidase inhibitor activity 1 GO:0004867 71 1 7.9922e-01 molecular_function serine-type endopeptidase inhibitor activity 1 GO:0046530 102 4 2.0022e-01 biological_process photoreceptor cell differentiation 1 1 1 1 GO:0048547 40 1 5.9485e-01 biological_process gut morphogenesis 1 GO:0048546 40 1 5.9485e-01 biological_process digestive tract morphogenesis 1 GO:0009112 78 1 8.2869e-01 biological_process nucleobase metabolism 1 GO:0009117 162 3 7.0837e-01 biological_process nucleotide metabolism 1 1 1 GO:0001745 136 5 1.9538e-01 biological_process compound eye morphogenesis (sensu Endopterygota) 1 1 1 1 1 GO:0042386 30 1 4.9205e-01 biological_process hemocyte differentiation (sensu Arthropoda) 1 GO:0050808 32 1 5.1450e-01 biological_process synapse organization and biogenesis 1 GO:0043190 44 1 6.2990e-01 cellular_component ATP-binding cassette (ABC) transporter complex 1 GO:0048488 36 0 1.0000e+00 biological_process synaptic vesicle endocytosis GO:0030135 74 0 1.0000e+00 cellular_component coated vesicle GO:0030136 62 0 1.0000e+00 cellular_component clathrin-coated vesicle GO:0001653 52 1 6.9120e-01 molecular_function peptide receptor activity 1 GO:0031974 418 17 1.5124e-02 cellular_component membrane-enclosed lumen 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0031975 271 7 4.1189e-01 cellular_component envelope 1 1 1 1 1 1 1 GO:0019887 35 1 5.4634e-01 molecular_function protein kinase regulator activity 1 GO:0007351 50 2 3.1119e-01 biological_process regional subdivision 1 1 GO:0007350 104 4 2.0948e-01 biological_process blastoderm segmentation 1 1 1 1 GO:0048511 38 0 1.0000e+00 biological_process rhythmic process GO:0048513 657 17 3.1571e-01 biological_process organ development 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0048515 40 2 2.2826e-01 biological_process spermatid differentiation 1 1 GO:0006338 42 5 2.8529e-03 biological_process chromatin remodeling 1 1 1 1 1 GO:0006333 100 11 2.2071e-05 biological_process chromatin assembly or disassembly 1 1 1 1 1 1 1 1 1 1 2 GO:0043492 155 3 6.7998e-01 molecular_function ATPase activity, coupled to movement of substances 1 1 1 GO:0042592 80 1 8.3629e-01 biological_process homeostasis 2 GO:0042598 83 0 1.0000e+00 cellular_component vesicular fraction GO:0006486 83 2 5.5901e-01 biological_process protein amino acid glycosylation 1 1 GO:0008356 54 1 7.0487e-01 biological_process asymmetric cell division 1 GO:0043167 947 23 3.8746e-01 molecular_function ion binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0008355 40 1 5.9485e-01 biological_process olfactory learning 1 GO:0005684 41 6 3.8227e-04 cellular_component major (U2-dependent) spliceosome 1 1 1 1 1 1 GO:0005681 94 8 1.5000e-03 cellular_component spliceosome complex 1 1 1 1 1 1 1 1 GO:0048812 124 2 7.6976e-01 biological_process neurite morphogenesis 1 1 GO:0004222 73 0 1.0000e+00 molecular_function metalloendopeptidase activity GO:0001763 35 1 5.4634e-01 biological_process morphogenesis of a branching structure 1 GO:0008083 33 0 1.0000e+00 molecular_function growth factor activity GO:0008080 30 1 4.9205e-01 molecular_function N-acetyltransferase activity 1 GO:0008553 49 1 6.6950e-01 molecular_function hydrogen-exporting ATPase activity, phosphorylative mechanism 1 GO:0007612 44 1 6.2990e-01 biological_process learning 1 GO:0009144 69 1 7.8990e-01 biological_process purine nucleoside triphosphate metabolism 1 GO:0009145 68 1 7.8509e-01 biological_process purine nucleoside triphosphate biosynthesis 1 GO:0006928 266 3 9.3974e-01 biological_process cell motility 1 1 1 GO:0048112 47 1 6.5419e-01 biological_process oocyte anterior/posterior axis determination (sensu Insecta) 1 GO:0042625 97 2 6.4347e-01 molecular_function ATPase activity, coupled to transmembrane movement of ions 1 1 GO:0042626 155 3 6.7998e-01 molecular_function ATPase activity, coupled to transmembrane movement of substances 1 1 1 GO:0035295 80 2 5.3915e-01 biological_process tube development 1 1 GO:0042623 334 16 4.2780e-03 molecular_function ATPase activity, coupled 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0005096 47 0 1.0000e+00 molecular_function GTPase activator activity GO:0000785 106 9 7.8746e-04 cellular_component chromatin 1 1 1 1 1 1 1 1 2 GO:0042742 69 1 7.8990e-01 biological_process defense response to bacteria 1 GO:0007254 49 1 6.6950e-01 biological_process JNK cascade 1 GO:0045934 126 5 1.5804e-01 biological_process negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 1 1 1 1 GO:0006310 42 5 2.8529e-03 biological_process DNA recombination 1 1 1 1 1 GO:0006913 72 6 6.3083e-03 biological_process nucleocytoplasmic transport 1 1 1 1 1 1 GO:0006818 78 1 8.2869e-01 biological_process hydrogen transport 1 GO:0008238 114 2 7.2829e-01 molecular_function exopeptidase activity 1 1 GO:0005667 89 6 1.6474e-02 cellular_component transcription factor complex 1 1 1 1 1 1 GO:0008235 79 0 1.0000e+00 molecular_function metalloexopeptidase activity GO:0008234 97 3 3.7418e-01 molecular_function cysteine-type peptidase activity 1 1 1 GO:0009152 89 1 8.6653e-01 biological_process purine ribonucleotide biosynthesis 1 GO:0009150 90 1 8.6953e-01 biological_process purine ribonucleotide metabolism 1 GO:0031090 321 3 9.7644e-01 cellular_component organelle membrane 1 1 1 GO:0015294 63 0 1.0000e+00 molecular_function solute:cation symporter activity GO:0015297 32 0 1.0000e+00 molecular_function antiporter activity GO:0015296 39 0 1.0000e+00 molecular_function anion:cation symporter activity GO:0015291 218 1 9.9296e-01 molecular_function porter activity 1 GO:0015290 218 1 9.9296e-01 molecular_function electrochemical potential-driven transporter activity 1 GO:0015293 73 0 1.0000e+00 molecular_function symporter activity GO:0008202 137 1 9.5520e-01 biological_process steroid metabolism 1 GO:0005576 389 1 9.9986e-01 cellular_component extracellular region 1 GO:0015031 530 16 1.4792e-01 biological_process protein transport 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0042981 110 4 2.3791e-01 biological_process regulation of apoptosis 1 1 1 1 GO:0003779 131 3 5.6761e-01 molecular_function actin binding 1 1 1 GO:0003774 87 2 5.8452e-01 molecular_function motor activity 1 1 GO:0003777 50 2 3.1119e-01 molecular_function microtubule motor activity 1 1 GO:0042254 32 0 1.0000e+00 biological_process ribosome biogenesis and assembly GO:0005342 74 0 1.0000e+00 molecular_function organic acid transporter activity GO:0007270 48 0 1.0000e+00 biological_process nerve-nerve synaptic transmission GO:0007274 30 0 1.0000e+00 biological_process neuromuscular synaptic transmission GO:0007275 1527 42 1.0313e-01 biological_process development 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007276 463 19 9.6798e-03 biological_process gametogenesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007316 39 1 5.8558e-01 biological_process pole plasm RNA localization 1 GO:0007315 45 1 6.3818e-01 biological_process pole plasm assembly 1 GO:0007314 58 1 7.3043e-01 biological_process oocyte anterior/posterior axis determination 1 GO:0044267 2103 51 3.0916e-01 biological_process cellular protein metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0016023 89 0 1.0000e+00 cellular_component cytoplasmic membrane-bound vesicle GO:0016021 969 12 9.9337e-01 cellular_component integral to membrane 1 1 1 1 1 1 1 1 1 1 1 1 GO:0016020 1915 25 9.9948e-01 cellular_component membrane 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007442 36 1 5.5648e-01 biological_process hindgut morphogenesis 1 GO:0007447 45 0 1.0000e+00 biological_process imaginal disc pattern formation GO:0043234 1602 62 1.6028e-05 cellular_component protein complex 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0043235 38 1 5.7610e-01 cellular_component receptor complex 1 GO:0043232 745 31 8.5688e-04 cellular_component intracellular non-membrane-bound organelle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0043233 418 17 1.5124e-02 cellular_component organelle lumen 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0007444 309 11 9.3921e-02 biological_process imaginal disc development 1 1 1 1 1 1 1 1 1 1 1 GO:0005643 41 4 1.4553e-02 cellular_component nuclear pore 1 1 1 1 GO:0019320 51 2 3.1943e-01 biological_process hexose catabolism 1 1 GO:0006732 240 2 9.7234e-01 biological_process coenzyme metabolism 1 1 GO:0009310 52 0 1.0000e+00 biological_process amine catabolism GO:0006030 63 0 1.0000e+00 biological_process chitin metabolism GO:0008047 97 2 6.4347e-01 molecular_function enzyme activator activity 1 2 GO:0044262 278 2 9.8688e-01 biological_process cellular carbohydrate metabolism 1 1 GO:0016849 33 0 1.0000e+00 molecular_function phosphorus-oxygen lyase activity GO:0008594 50 2 3.1119e-01 biological_process photoreceptor cell morphogenesis (sensu Endopterygota) 1 1 GO:0008595 50 2 3.1119e-01 biological_process determination of anterior/posterior axis, embryo 1 1 GO:0016271 73 1 8.0812e-01 biological_process tissue death 1 GO:0030154 532 18 5.9145e-02 biological_process cell differentiation 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0016627 30 1 4.9205e-01 molecular_function oxidoreductase activity, acting on the CH-CH group of donors 1 GO:0042277 65 1 7.6996e-01 molecular_function peptide binding 1 GO:0006508 764 18 4.5887e-01 biological_process proteolysis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0051188 105 1 9.0720e-01 biological_process cofactor biosynthesis 1 GO:0009058 911 19 6.7042e-01 biological_process biosynthesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0009059 531 12 5.3791e-01 biological_process macromolecule biosynthesis 1 1 1 1 1 1 1 1 1 1 1 1 GO:0051170 49 6 9.5956e-04 biological_process nuclear import 1 1 1 1 1 1 GO:0031967 271 7 4.1189e-01 cellular_component organelle envelope 1 1 1 1 1 1 1 GO:0050684 55 7 2.9210e-04 biological_process regulation of mRNA processing 1 1 1 1 1 1 1 GO:0007292 322 15 7.1254e-03 biological_process female gamete generation 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007293 48 5 4.9909e-03 biological_process egg chamber formation (sensu Insecta) 1 1 1 1 1 GO:0007297 34 1 5.3597e-01 biological_process follicle cell migration (sensu Insecta) 1 GO:0018193 35 1 5.4634e-01 biological_process peptidyl-amino acid modification 1 GO:0016049 30 2 1.4760e-01 biological_process cell growth 1 1 GO:0016044 32 0 1.0000e+00 biological_process membrane organization and biogenesis GO:0016043 1417 52 3.2459e-04 biological_process cell organization and biogenesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0042067 35 1 5.4634e-01 biological_process establishment of ommatidial polarity (sensu Endopterygota) 1 GO:0043037 189 5 4.2270e-01 biological_process translation 1 1 1 1 1 GO:0008340 48 0 1.0000e+00 biological_process determination of adult life span GO:0008610 85 3 3.0083e-01 biological_process lipid biosynthesis 1 1 1 GO:0005624 93 0 1.0000e+00 cellular_component membrane fraction GO:0005623 4695 125 1.3532e-02 cellular_component cell 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 GO:0005622 3346 110 7.3332e-06 cellular_component intracellular 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 GO:0045941 66 2 4.3874e-01 biological_process positive regulation of transcription 1 1 GO:0048066 40 0 1.0000e+00 biological_process pigmentation during development GO:0009993 289 15 2.7058e-03 biological_process oogenesis (sensu Insecta) 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0005198 757 12 9.2379e-01 molecular_function structural molecule activity 1 1 1 1 1 1 1 1 1 1 1 1 GO:0008066 40 1 5.9485e-01 molecular_function glutamate receptor activity 1 GO:0008061 63 0 1.0000e+00 molecular_function chitin binding GO:0008063 30 0 1.0000e+00 biological_process Toll signaling pathway GO:0000004 728 5 9.9978e-01 biological_process biological process unknown 1 1 1 1 2 GO:0043119 165 7 8.2473e-02 biological_process positive regulation of physiological process 1 1 1 1 1 1 1 GO:0004714 32 0 1.0000e+00 molecular_function transmembrane receptor protein tyrosine kinase activity GO:0004713 90 3 3.3144e-01 molecular_function protein-tyrosine kinase activity 1 2 2 GO:0003924 133 3 5.7784e-01 molecular_function GTPase activity 1 1 1 GO:0043118 231 7 2.6809e-01 biological_process negative regulation of physiological process 1 1 1 1 1 1 1 GO:0016787 1828 51 6.3490e-02 molecular_function hydrolase activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0016788 463 13 2.4935e-01 molecular_function hydrolase activity, acting on ester bonds 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0016789 124 1 9.3976e-01 molecular_function carboxylic ester hydrolase activity 1 GO:0015075 493 3 9.9905e-01 molecular_function ion transporter activity 1 1 1 GO:0015077 105 1 9.0720e-01 molecular_function monovalent inorganic cation transporter activity 1 GO:0015078 103 1 9.0289e-01 molecular_function hydrogen ion transporter activity 1 GO:0048024 55 7 2.9210e-04 biological_process regulation of nuclear mRNA splicing, via spliceosome 1 1 1 1 1 1 1 GO:0007126 90 11 8.4392e-06 biological_process meiosis 1 1 1 1 1 1 1 1 1 1 2 GO:0007127 32 6 1.0225e-04 biological_process meiosis I 1 1 1 1 1 2 GO:0016251 103 4 2.0484e-01 molecular_function general RNA polymerase II transcription factor activity 1 1 1 1 GO:0007417 124 5 1.5096e-01 biological_process central nervous system development 1 1 1 1 1 GO:0006520 263 3 9.3668e-01 biological_process amino acid metabolism 1 1 1 GO:0003735 189 3 7.9994e-01 molecular_function structural constituent of ribosome 1 1 1 GO:0043067 120 4 2.8705e-01 biological_process regulation of programmed cell death 1 1 1 1 GO:0043066 42 1 6.1277e-01 biological_process negative regulation of apoptosis 1 GO:0043069 42 1 6.1277e-01 biological_process negative regulation of programmed cell death 1 GO:0043068 76 3 2.4630e-01 biological_process positive regulation of programmed cell death 1 1 1 GO:0000279 296 23 4.0148e-07 biological_process M phase 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0000278 278 17 2.4003e-04 biological_process mitotic cell cycle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0051119 47 1 6.5419e-01 molecular_function sugar transporter activity 1 GO:0004386 112 12 1.2164e-05 molecular_function helicase activity 1 1 1 1 1 1 1 1 1 1 1 1 GO:0005386 458 7 8.9335e-01 molecular_function carrier activity 1 1 1 1 1 1 1 GO:0016820 156 3 6.8415e-01 molecular_function hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 1 1 1 GO:0006897 121 3 5.1426e-01 biological_process endocytosis 1 1 1 GO:0016065 53 0 1.0000e+00 biological_process humoral defense mechanism (sensu Protostomia) GO:0007517 111 3 4.5761e-01 biological_process muscle development 1 1 1 GO:0042048 55 1 7.1148e-01 biological_process olfactory behavior 1 GO:0006725 147 2 8.4478e-01 biological_process aromatic compound metabolism 1 1 GO:0005813 36 2 1.9542e-01 cellular_component centrosome 1 2 GO:0005815 42 4 1.5751e-02 cellular_component microtubule organizing center 1 1 1 2 GO:0005975 488 5 9.8621e-01 biological_process carbohydrate metabolism 1 1 1 1 1 GO:0030054 68 4 6.9466e-02 cellular_component cell junction 1 1 1 1 GO:0007617 56 1 7.1794e-01 biological_process mating behavior 1 GO:0007611 61 3 1.6035e-01 biological_process learning and/or memory 1 1 1 GO:0007243 134 3 5.8290e-01 biological_process protein kinase cascade 1 1 1 GO:0000398 152 13 5.3828e-05 biological_process nuclear mRNA splicing, via spliceosome 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0004553 102 1 9.0066e-01 molecular_function hydrolase activity, hydrolyzing O-glycosyl compounds 1 GO:0016881 158 6 1.4976e-01 molecular_function acid-amino acid ligase activity 1 1 1 1 1 2 GO:0016887 375 22 5.4892e-05 molecular_function ATPase activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0014016 30 0 1.0000e+00 biological_process neuroblast differentiation GO:0014017 30 0 1.0000e+00 biological_process neuroblast fate commitment GO:0004812 60 3 1.5498e-01 molecular_function aminoacyl-tRNA ligase activity 1 1 1 GO:0045333 48 0 1.0000e+00 biological_process cellular respiration GO:0009719 137 13 1.8793e-05 biological_process response to endogenous stimulus 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0051321 95 12 2.3647e-06 biological_process meiotic cell cycle 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007552 259 10 7.1532e-02 biological_process metamorphosis 1 1 1 1 1 1 1 1 1 1 GO:0015276 70 0 1.0000e+00 molecular_function ligand-gated ion channel activity GO:0019941 77 4 9.8201e-02 biological_process modification-dependent protein catabolism 1 1 1 1 GO:0007143 39 2 2.2000e-01 biological_process female meiosis 1 2 GO:0050789 1531 65 4.1833e-07 biological_process regulation of biological process 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0030198 32 1 5.1450e-01 biological_process extracellular matrix organization and biogenesis 1 GO:0030286 40 0 1.0000e+00 cellular_component dynein complex GO:0016879 182 6 2.3050e-01 molecular_function ligase activity, forming carbon-nitrogen bonds 1 1 1 1 1 2 GO:0008639 34 1 5.3597e-01 molecular_function small protein conjugating enzyme activity 1 GO:0040007 91 2 6.0893e-01 biological_process growth 1 1 GO:0044248 309 8 3.9664e-01 biological_process cellular catabolism 1 1 1 1 1 1 1 1 GO:0044249 842 14 9.0835e-01 biological_process cellular biosynthesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0048646 30 0 1.0000e+00 biological_process anatomical structure formation GO:0007439 40 1 5.9485e-01 biological_process ectodermal gut development 1 GO:0005830 91 1 8.7246e-01 cellular_component cytosolic ribosome (sensu Eukaryota) 1 GO:0007088 37 5 1.6572e-03 biological_process regulation of mitosis 1 1 1 1 1 GO:0015849 55 0 1.0000e+00 biological_process organic acid transport GO:0005488 4219 135 1.2118e-06 molecular_function binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 2 GO:0042923 49 1 6.6950e-01 molecular_function neuropeptide binding 1 GO:0004536 38 3 5.5725e-02 molecular_function deoxyribonuclease activity 1 1 1 GO:0006752 72 1 8.0372e-01 biological_process group transfer coenzyme metabolism 1 GO:0006753 64 1 7.6469e-01 biological_process nucleoside phosphate metabolism 1 GO:0006754 64 1 7.6469e-01 biological_process ATP biosynthesis 1 GO:0008021 56 0 1.0000e+00 cellular_component synaptic vesicle GO:0008026 83 10 2.4403e-05 molecular_function ATP-dependent helicase activity 1 1 1 1 1 1 1 1 1 1 GO:0008283 288 11 6.4521e-02 biological_process cell proliferation 1 1 1 1 1 1 1 1 1 1 1 GO:0008289 68 4 6.9466e-02 molecular_function lipid binding 1 1 1 1 GO:0051301 145 6 1.1249e-01 biological_process cell division 1 1 1 1 1 1 GO:0019219 906 39 9.0455e-05 biological_process regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0019748 70 0 1.0000e+00 biological_process secondary metabolism GO:0035272 110 1 9.1717e-01 biological_process exocrine system development 1 GO:0007160 31 1 5.0340e-01 biological_process cell-matrix adhesion 1 GO:0007163 75 3 2.4033e-01 biological_process establishment and/or maintenance of cell polarity 1 1 1 GO:0007164 46 1 6.4628e-01 biological_process establishment of tissue polarity 1 GO:0007165 1337 27 7.5414e-01 biological_process signal transduction 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0007166 684 12 8.4862e-01 biological_process cell surface receptor linked signal transduction 1 1 1 1 1 1 1 1 1 1 1 1 GO:0007167 176 7 1.0617e-01 biological_process enzyme linked receptor protein signaling pathway 1 1 1 1 1 1 1 GO:0007169 127 6 6.9953e-02 biological_process transmembrane receptor protein tyrosine kinase signaling pathway 1 1 1 1 1 1 GO:0016740 988 27 1.7546e-01 molecular_function transferase activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0016741 87 3 3.1306e-01 molecular_function transferase activity, transferring one-carbon groups 1 1 1 GO:0016746 130 1 9.4746e-01 molecular_function transferase activity, transferring acyl groups 1 GO:0016747 123 1 9.3838e-01 molecular_function transferase activity, transferring groups other than amino-acyl groups 1 GO:0016567 113 3 4.6918e-01 biological_process protein ubiquitination 1 1 1 GO:0016564 60 2 3.9219e-01 molecular_function transcriptional repressor activity 1 1 GO:0016563 56 3 1.3412e-01 molecular_function transcriptional activator activity 1 1 1 GO:0016298 88 0 1.0000e+00 molecular_function lipase activity GO:0016568 61 6 2.8584e-03 biological_process chromatin modification 1 1 1 1 1 1 GO:0015985 64 1 7.6469e-01 biological_process energy coupled proton transport, down electrochemical gradient 1 GO:0015986 64 1 7.6469e-01 biological_process ATP synthesis coupled proton transport 1 GO:0015980 119 2 7.4976e-01 biological_process energy derivation by oxidation of organic compounds 1 1 GO:0046394 31 0 1.0000e+00 biological_process carboxylic acid biosynthesis GO:0051243 222 7 2.3765e-01 biological_process negative regulation of cellular physiological process 1 1 1 1 1 1 1 GO:0051246 135 3 5.8792e-01 biological_process regulation of protein metabolism 1 1 1 GO:0009259 92 1 8.7532e-01 biological_process ribonucleotide metabolism 1 GO:0045271 38 0 1.0000e+00 cellular_component respiratory chain complex I GO:0040029 75 5 2.8683e-02 biological_process regulation of gene expression, epigenetic 1 1 1 1 1 GO:0015405 122 2 7.6193e-01 molecular_function P-P-bond-hydrolysis-driven transporter activity 1 1 GO:0007455 149 6 1.2340e-01 biological_process eye-antennal disc morphogenesis 1 1 1 1 1 1 GO:0009994 91 4 1.5187e-01 biological_process oocyte differentiation 1 1 1 1 GO:0005856 293 10 1.2978e-01 cellular_component cytoskeleton 1 1 1 1 1 1 1 1 1 2 GO:0005938 49 1 6.6950e-01 cellular_component cell cortex 1 GO:0007519 50 0 1.0000e+00 biological_process striated muscle development GO:0030528 826 28 2.1659e-02 molecular_function transcription regulator activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0030529 322 12 6.3791e-02 cellular_component ribonucleoprotein complex 1 1 1 1 1 1 1 1 1 1 1 1 GO:0004518 91 7 5.0240e-03 molecular_function nuclease activity 1 1 1 1 1 1 1 GO:0004519 50 4 2.7571e-02 molecular_function endonuclease activity 1 1 1 1 GO:0006006 60 2 3.9219e-01 biological_process glucose metabolism 1 1 GO:0006007 51 2 3.1943e-01 biological_process glucose catabolism 1 1 GO:0005200 305 7 5.3362e-01 molecular_function structural constituent of cytoskeleton 1 1 1 1 1 1 1 GO:0042706 35 1 5.4634e-01 biological_process eye photoreceptor cell fate commitment 1 GO:0043169 902 23 3.0168e-01 molecular_function cation binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0048666 146 2 8.4204e-01 biological_process neuron development 1 1 GO:0048667 124 2 7.6976e-01 biological_process neuron morphogenesis during differentiation 1 1 GO:0043062 43 2 2.5313e-01 biological_process extracellular structure organization and biogenesis 1 1 GO:0000502 54 5 8.0732e-03 cellular_component proteasome complex (sensu Eukaryota) 1 1 1 1 1 GO:0019725 70 0 1.0000e+00 biological_process cell homeostasis GO:0019722 66 1 7.7512e-01 biological_process calcium-mediated signaling 1 GO:0006898 39 1 5.8558e-01 biological_process receptor mediated endocytosis 1 GO:0016765 61 1 7.4814e-01 molecular_function transferase activity, transferring alkyl or aryl (other than methyl) groups 1 GO:0044264 78 0 1.0000e+00 biological_process cellular polysaccharide metabolism GO:0044265 174 6 2.0211e-01 biological_process cellular macromolecule catabolism 1 1 1 1 1 1 GO:0044260 2177 52 3.4879e-01 biological_process cellular macromolecule metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0006413 59 0 1.0000e+00 biological_process translational initiation GO:0017145 38 1 5.7610e-01 biological_process stem cell division 1 GO:0002009 139 5 2.0714e-01 biological_process morphogenesis of an epithelium 1 1 1 1 1 GO:0009581 45 0 1.0000e+00 biological_process detection of external stimulus GO:0009582 44 0 1.0000e+00 biological_process detection of abiotic stimulus GO:0009583 35 0 1.0000e+00 biological_process detection of light stimulus GO:0008188 49 1 6.6950e-01 molecular_function neuropeptide receptor activity 1 GO:0008186 40 2 2.2826e-01 molecular_function RNA-dependent ATPase activity 1 1 GO:0000165 109 3 4.4595e-01 biological_process MAPKKK cascade 1 1 1 GO:0000166 895 43 2.7001e-06 molecular_function nucleotide binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 GO:0019538 2208 59 9.1108e-02 biological_process protein metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 GO:0004091 32 0 1.0000e+00 molecular_function carboxylesterase activity GO:0000578 59 2 3.8426e-01 biological_process embryonic axis specification 1 1 GO:0015399 122 2 7.6193e-01 molecular_function primary active transporter activity 1 1 GO:0015171 47 0 1.0000e+00 molecular_function amino acid transporter activity GO:0005871 30 2 1.4760e-01 cellular_component kinesin complex 1 1 GO:0005874 43 1 6.2143e-01 cellular_component microtubule 1 GO:0005875 117 3 4.9196e-01 cellular_component microtubule associated complex 1 1 1 GO:0005912 51 1 6.8413e-01 cellular_component adherens junction 1 GO:0005911 46 3 8.7015e-02 cellular_component intercellular junction 1 1 1 GO:0030030 50 0 1.0000e+00 biological_process cell projection organization and biogenesis GO:0030031 32 0 1.0000e+00 biological_process cell projection biogenesis GO:0030036 102 3 4.0440e-01 biological_process actin cytoskeleton organization and biogenesis 1 1 1 GO:0007608 74 0 1.0000e+00 biological_process sensory perception of smell GO:0006606 48 6 8.6383e-04 biological_process protein import into nucleus 1 1 1 1 1 1 GO:0000375 152 13 5.3828e-05 biological_process RNA splicing, via transesterification reactions 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0000377 152 13 5.3828e-05 biological_process RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0006605 238 10 4.5699e-02 biological_process protein targeting 1 1 1 1 1 1 1 1 1 1 GO:0006793 615 16 3.1533e-01 biological_process phosphorus metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0005267 53 0 1.0000e+00 molecular_function potassium channel activity GO:0005261 117 0 1.0000e+00 molecular_function cation channel activity GO:0000087 233 17 2.9398e-05 biological_process M phase of mitotic cell cycle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0006470 86 1 8.5713e-01 biological_process protein amino acid dephosphorylation 1 GO:0016830 45 2 2.6975e-01 molecular_function carbon-carbon lyase activity 1 1 GO:0045055 110 0 1.0000e+00 biological_process regulated secretory pathway GO:0008168 86 3 3.0694e-01 molecular_function methyltransferase activity 1 1 1 GO:0006813 60 0 1.0000e+00 biological_process potassium ion transport GO:0006812 390 2 9.9866e-01 biological_process cation transport 1 1 GO:0006811 470 3 9.9851e-01 biological_process ion transport 1 1 1 GO:0006817 43 0 1.0000e+00 biological_process phosphate transport GO:0006814 46 0 1.0000e+00 biological_process sodium ion transport GO:0003824 3835 93 2.2208e-01 molecular_function catalytic activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 GO:0006959 79 1 8.3253e-01 biological_process humoral immune response 1 GO:0051082 62 0 1.0000e+00 molecular_function unfolded protein binding GO:0015370 62 0 1.0000e+00 molecular_function solute:sodium symporter activity GO:0007028 56 1 7.1794e-01 biological_process cytoplasm organization and biogenesis 1 GO:0046034 65 1 7.6996e-01 biological_process ATP metabolism 1 GO:0030234 365 7 7.1764e-01 molecular_function enzyme regulator activity 1 1 1 1 1 1 2 GO:0019222 1043 42 2.0191e-04 biological_process regulation of metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0005057 242 11 2.2969e-02 molecular_function receptor signaling protein activity 1 1 1 1 1 1 1 1 2 2 2 GO:0031982 92 0 1.0000e+00 cellular_component vesicle GO:0031981 259 15 9.4880e-04 cellular_component nuclear lumen 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0031988 92 0 1.0000e+00 cellular_component membrane-bound vesicle GO:0006260 122 9 2.0489e-03 biological_process DNA replication 1 1 1 1 1 1 1 1 1 GO:0006261 62 5 1.3956e-02 biological_process DNA-dependent DNA replication 1 1 1 1 1 GO:0005794 91 1 8.7246e-01 cellular_component Golgi apparatus 1 GO:0000314 30 1 4.9205e-01 cellular_component organellar small ribosomal subunit 1 GO:0048748 144 5 2.2723e-01 biological_process eye morphogenesis (sensu Endopterygota) 1 1 1 1 1 GO:0009975 32 0 1.0000e+00 molecular_function cyclase activity GO:0005275 54 0 1.0000e+00 molecular_function amine transporter activity GO:0048477 301 15 3.9263e-03 biological_process oogenesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0006040 73 0 1.0000e+00 biological_process amino sugar metabolism GO:0001700 131 3 5.6761e-01 biological_process embryonic development (sensu Insecta) 1 1 1 GO:0005249 33 0 1.0000e+00 molecular_function voltage-gated potassium channel activity GO:0005244 51 1 6.8413e-01 molecular_function voltage-gated ion channel activity 1 GO:0009791 362 11 1.9822e-01 biological_process post-embryonic development 1 1 1 1 1 1 1 1 1 1 1 GO:0009790 360 12 1.1783e-01 biological_process embryonic development 1 1 1 1 1 1 1 1 1 1 1 1 GO:0009792 199 4 6.5757e-01 biological_process embryonic development (sensu Metazoa) 1 1 1 1 GO:0009798 163 5 3.0784e-01 biological_process axis specification 1 1 1 1 1 GO:0048741 43 0 1.0000e+00 biological_process skeletal muscle fiber development GO:0008415 117 1 9.2936e-01 molecular_function acyltransferase activity 1 GO:0015631 92 2 6.1486e-01 molecular_function tubulin binding 1 1 GO:0015630 192 7 1.4642e-01 cellular_component microtubule cytoskeleton 1 1 1 1 1 1 2 GO:0046483 142 1 9.6002e-01 biological_process heterocycle metabolism 1 GO:0009892 155 5 2.7323e-01 biological_process negative regulation of metabolism 1 1 1 1 1 GO:0009893 69 2 4.6128e-01 biological_process positive regulation of metabolism 1 1 GO:0000122 53 1 6.9811e-01 biological_process negative regulation of transcription from RNA polymerase II promoter 1 GO:0008324 405 2 9.9902e-01 molecular_function cation transporter activity 1 1 GO:0009636 130 0 1.0000e+00 biological_process response to toxin GO:0007001 159 18 3.6894e-08 biological_process chromosome organization and biogenesis (sensu Eukaryota) 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0009314 55 1 7.1148e-01 biological_process response to radiation 1 GO:0046356 48 0 1.0000e+00 biological_process acetyl-CoA catabolism GO:0006206 32 0 1.0000e+00 biological_process pyrimidine base metabolism GO:0009953 76 2 5.1174e-01 biological_process dorsal/ventral pattern formation 1 1 GO:0009952 133 3 5.7784e-01 biological_process anterior/posterior pattern formation 1 1 1 GO:0009950 58 2 3.7629e-01 biological_process dorsal/ventral axis specification 1 1 GO:0050896 1192 31 2.2873e-01 biological_process response to stimulus 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0031098 49 1 6.6950e-01 biological_process stress-activated protein kinase signaling pathway 1 GO:0009408 47 1 6.5419e-01 biological_process response to heat 1 GO:0005516 72 0 1.0000e+00 molecular_function calmodulin binding GO:0005515 1266 35 1.2292e-01 molecular_function protein binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0004177 42 0 1.0000e+00 molecular_function aminopeptidase activity GO:0004175 480 11 5.2098e-01 molecular_function endopeptidase activity 1 1 1 1 1 1 1 1 1 1 1 GO:0006996 743 36 1.5871e-05 biological_process organelle organization and biogenesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0035107 136 5 1.9538e-01 biological_process appendage morphogenesis 1 1 1 1 1 GO:0035220 120 5 1.3721e-01 biological_process wing disc development 1 1 1 1 1 GO:0051603 82 4 1.1621e-01 biological_process proteolysis during cellular protein catabolism 1 1 1 1 GO:0051606 49 0 1.0000e+00 biological_process detection of stimulus GO:0007619 34 0 1.0000e+00 biological_process courtship behavior GO:0043283 1705 81 4.5396e-11 biological_process biopolymer metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 GO:0043285 128 6 7.2024e-02 biological_process biopolymer catabolism 1 1 1 1 1 1 GO:0042462 46 2 2.7805e-01 biological_process eye photoreceptor cell development 1 1 GO:0042461 53 2 3.3584e-01 biological_process photoreceptor cell development 1 1 GO:0006858 124 0 1.0000e+00 biological_process extracellular transport GO:0046914 687 21 9.9707e-02 molecular_function transition metal ion binding 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0007459 43 2 2.5313e-01 biological_process photoreceptor fate commitment (sensu Endopterygota) 1 1 GO:0009613 101 1 8.9837e-01 biological_process response to pest, pathogen or parasite 1 GO:0007067 232 17 2.7879e-05 biological_process mitosis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0006163 92 1 8.7532e-01 biological_process purine nucleotide metabolism 1 GO:0016684 32 0 1.0000e+00 molecular_function oxidoreductase activity, acting on peroxide as acceptor GO:0006164 91 1 8.7246e-01 biological_process purine nucleotide biosynthesis 1 GO:0016462 538 25 6.0519e-04 molecular_function pyrophosphatase activity 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0016469 68 1 7.8509e-01 cellular_component proton-transporting two-sector ATPase complex 1 GO:0007635 56 1 7.1794e-01 biological_process chemosensory behavior 1 GO:0006084 49 0 1.0000e+00 biological_process acetyl-CoA metabolism GO:0006082 394 3 9.9371e-01 biological_process organic acid metabolism 1 1 1 GO:0030097 64 1 7.6469e-01 biological_process hemopoiesis 1 GO:0031326 80 2 5.3915e-01 biological_process regulation of cellular biosynthesis 1 1 GO:0031325 69 2 4.6128e-01 biological_process positive regulation of cellular metabolism 1 1 GO:0031324 145 5 2.3132e-01 biological_process negative regulation of cellular metabolism 1 1 1 1 1 GO:0031323 1005 41 1.8491e-04 biological_process regulation of cellular metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0005759 148 2 8.4747e-01 cellular_component mitochondrial matrix 1 1 GO:0005575 5903 136 3.9201e-01 cellular_component cellular_component 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 2 GO:0005578 46 0 1.0000e+00 cellular_component extracellular matrix (sensu Metazoa) GO:0007591 32 0 1.0000e+00 biological_process molting cycle (sensu Insecta) GO:0001505 122 0 1.0000e+00 biological_process regulation of neurotransmitter levels GO:0004620 41 0 1.0000e+00 molecular_function phospholipase activity GO:0000904 173 4 5.4828e-01 biological_process cellular morphogenesis during differentiation 1 1 1 1 GO:0000902 350 9 3.9245e-01 biological_process cellular morphogenesis 1 1 1 1 1 1 1 1 1 GO:0043413 83 2 5.5901e-01 biological_process biopolymer glycosylation 1 1 GO:0015674 40 0 1.0000e+00 biological_process di-, tri-valent inorganic cation transport GO:0015672 179 1 9.8282e-01 biological_process monovalent inorganic cation transport 1 GO:0015926 31 1 5.0340e-01 molecular_function glucosidase activity 1 GO:0016327 39 3 5.9285e-02 cellular_component apicolateral plasma membrane 1 1 1 GO:0046930 41 4 1.4553e-02 cellular_component pore complex 1 1 1 1 GO:0048599 84 2 5.6549e-01 biological_process oocyte development 1 1 GO:0048592 152 5 2.6048e-01 biological_process eye morphogenesis 1 1 1 1 1 GO:0006418 61 3 1.6035e-01 biological_process tRNA aminoacylation for protein translation 1 1 1 GO:0006417 76 2 5.1174e-01 biological_process regulation of protein biosynthesis 1 1 GO:0006144 55 1 7.1148e-01 biological_process purine base metabolism 1 GO:0008105 35 3 4.5690e-02 biological_process asymmetric protein localization 1 1 2 GO:0008104 581 19 6.9675e-02 biological_process protein localization 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0046933 63 1 7.5930e-01 molecular_function hydrogen-transporting ATP synthase activity, rotational mechanism 1 GO:0004364 37 0 1.0000e+00 molecular_function glutathione transferase activity GO:0019897 36 0 1.0000e+00 cellular_component extrinsic to plasma membrane GO:0051179 2131 37 9.6877e-01 biological_process localization 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 GO:0009165 110 2 7.1002e-01 biological_process nucleotide biosynthesis 1 1 GO:0019318 81 2 5.4584e-01 biological_process hexose metabolism 1 1 GO:0031966 188 2 9.2588e-01 cellular_component mitochondrial membrane 1 1 GO:0046552 43 2 2.5313e-01 biological_process photoreceptor cell fate commitment 1 1 GO:0007046 30 0 1.0000e+00 biological_process ribosome biogenesis GO:0007049 483 30 7.5828e-07 biological_process cell cycle 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 2 GO:0043473 40 0 1.0000e+00 biological_process pigmentation GO:0008380 158 13 7.9031e-05 biological_process RNA splicing 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0016407 49 1 6.6950e-01 molecular_function acetyltransferase activity 1 GO:0006066 163 3 7.1226e-01 biological_process alcohol metabolism 1 1 1 GO:0006796 615 16 3.1533e-01 biological_process phosphate metabolism 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 2 GO:0006790 60 0 1.0000e+00 biological_process sulfur metabolism GO:0005773 54 0 1.0000e+00 cellular_component vacuole GO:0005777 35 1 5.4634e-01 cellular_component peroxisome 1 GO:0001584 228 3 8.8887e-01 molecular_function rhodopsin-like receptor activity 1 1 1 GO:0007530 45 6 6.2020e-04 biological_process sex determination 1 1 1 1 1 1 GO:0006952 516 5 9.9118e-01 biological_process defense response 1 1 1 1 1 GO:0006950 340 18 8.4986e-04 biological_process response to stress 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0006955 123 1 9.3838e-01 biological_process immune response 1 GO:0004601 32 0 1.0000e+00 molecular_function peroxidase activity GO:0007389 264 7 3.8628e-01 biological_process pattern specification 1 1 1 1 1 1 1 GO:0015698 54 1 7.0487e-01 biological_process inorganic anion transport 1 GO:0051649 648 19 1.4904e-01 biological_process establishment of cellular localization 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0051640 32 2 1.6328e-01 biological_process organelle localization 1 1 GO:0051641 649 19 1.5051e-01 biological_process cellular localization 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 GO:0008527 56 1 7.1794e-01 molecular_function taste receptor activity 1 GO:0009653 658 17 3.1789e-01 biological_process morphogenesis 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 GO:0008528 52 1 6.9120e-01 molecular_function peptide receptor activity, G-protein coupled 1 GO:0048519 298 7 5.0920e-01 biological_process negative regulation of biological process 1 1 1 1 1 1 1 GO:0006041 72 0 1.0000e+00 biological_process glucosamine metabolism GO:0019199 52 0 1.0000e+00 molecular_function transmembrane receptor protein kinase activity